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- Table of Contents
Smarcad1 Antibodies
AND Smarcad1 ELISA kits, Smarcad1 Proteins
Many biological assays use antibodies to detect Smarcad1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smarcad1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smarcad1 antibodies...
Designing an IHC experiment for Smarcad1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SMARCAD1 IHC GuideSmarcad1 Infographic by Boster Bio
All Smarcad1 Products
Product
Figures
Specificity
Applications
Price
Anti-SMARCAD1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A06049-1
100 μg/vial
Cat # A06049-1
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06060-3
100 μg/vial
Cat # A06060-3
100 μg/vial
Smarcad1 Overview
Facts about SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (Smarcad1)
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling action and is both required for DNA repair and heterochromatin organization. Encourages DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.
Required for the restoration of heterochromatin organization after replication. Acts at replication sites to ease the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3'Lys-9' trimethylation (H3K9me3) and restoration of silencing (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Smarcad1 |
| Uniprot: | Q04692 |
| Entrez: | 13990 |
Family
| Belongs to: |
|---|
| SNF2/RAD54 helicase family |
Alternative Names
ATP-dependent helicase 1; DKFZP762K2015; EC 3.6.1; EC 3.6.4.12; HEL1; hHEL1; KIAA1122ETL1DKFZp762K2015; subfamily a, containing DEAD/H box 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin
Molecular Weight
Mass (kDA):
116.451 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6 C1|6 30.11 cM |
| Sequence: | 6; |
Diseases
- Malignant Neoplasms
- Carcinoma
- Liver Carcinoma
- Carcinogenesis
- Neoplasms
- Nervousness
- Malignant Squamous Cell Neoplasm
- Hematologic Neoplasms
- Leiomyosarcoma
- Hepatitis
- Genomic Instability
- Head And Neck Carcinoma
- Hepatitis B
Pathways
- Chromatin Remodeling
- Localization
- Dna Replication
- Histone Deacetylation
- Atp-dependent Chromatin Remodeling
- Cell Proliferation
- Dna Repair
- Neurogenesis
- Chromosome Segregation
- Rna Splicing
- Methylation
PTMs
- Deacetylation
Research Areas
- DNA Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smarcad1
bosterbio.com/bosterbio-gene-info-cards/Smarcad1
References
PMID: 1489724 by Soininen R., et al. The mouse Enhancer trap locus 1 (Etl-1): a novel mammalian gene related to Drosophila and yeast transcriptional regulator genes.
PMID: 8219362 by Schoor M., et al. The Etl-1 gene encodes a nuclear protein differentially expressed during early mouse development.