SWI/SNF complex subunit SMARCC1 (SMARCC1)

Component of SWI/SNF chromatin remodeling complexes that carry out crucial enzymatic actions, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. May stimulate the ATPase activity of the catalytic subunit of the complex (PubMed:10078207, PubMed:29374058).

Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a change from a stem/progenitor into a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become dedicated to their adult condition.