This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
SMARCC2 Antibodies
AND SMARCC2 ELISA kits, SMARCC2 Proteins
Many biological assays use antibodies to detect SMARCC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMARCC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMARCC2 antibodies...
Designing a Western blot for SMARCC2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SMARCC2 Western Blot GuideSMARCC2 Infographic by Boster Bio
All SMARCC2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1879
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1879
1 kit, containing one 96-well plate and all necessary reagents
SMARCC2 Overview
Facts about SWI/SNF complex subunit SMARCC2.
SWI/SNF complex subunit SMARCC2 (SMARCC2)
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Part of SWI/SNF chromatin remodeling complexes that carry out crucial enzymatic activities, changing chromatin structure by changing DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:11018012).
Can stimulate the ATPase activity of the catalytic subunit of those complexes (PubMed:10078207). May be necessary for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells (PubMed:12192000).
Gene Information
| Human | |
|---|---|
| Gene Name: | SMARCC2 |
| Uniprot: | Q8TAQ2 |
| Entrez: | 6601 |
Family
| Belongs to: |
|---|
| SMARCC family |
Alternative Names
BAF170DKFZp313D0632; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; subfamily c, member 2; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin; SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily C member 2; SWI3-like protein
Molecular Weight
Mass (kDA):
132.879 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.2 |
| Sequence: | 12; NC_000012.12 (56162359..56189504, complement) |
Tissue Specificity
Ubiquitously expressed.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Mammary Neoplasms
- Embryonal Carcinoma
- Melanoma
- Malignant Neoplasm Of Breast
- Glucocorticoid Deficiency With Achalasia
- Seminoma
- Neoplasm Invasiveness
- Neoplasms, Germ Cell And Embryonal
- Carcinoma
- Immunologic Deficiency Syndromes
Interacting Proteins
- CHD7
- TERF2IP
Pathways
- Chromatin Remodeling
- Dna Repair
- Cell Adhesion
- Neural Tube Closure
- Cell Proliferation
- Atp-dependent Chromatin Remodeling
- Hypersensitivity
- Neurogenesis
- Methylation
- Tube Closure
- Viral Transcription
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMARCC2
bosterbio.com/bosterbio-gene-info-cards/SMARCC2
References
PMID: 8804307 by Wang W., et al. Diversity and specialization of mammalian SWI/SNF complexes.
PMID: 10078207 by Phelan M.L., et al. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.