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Protein sprouty homolog 4 Antibodies
AND Spry4 ELISA kits, Protein sprouty homolog 4 Proteins
Many biological assays use antibodies to detect Protein sprouty homolog 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein sprouty homolog 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein sprouty homolog 4 antibodies...
Designing a Western blot for Protein sprouty homolog 4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SPRY4 Western Blot GuideDesigning an IHC experiment for Protein sprouty homolog 4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SPRY4 IHC GuideSpry4 Infographic by Boster Bio
All Spry4 Products
Product
Figures
Specificity
Applications
Price
Anti-Sprouty 4/Spry-4/SPRY4 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04343-2
100 μg/vial
Cat # A04343-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M04343
100 μl/vial
Cat # M04343
100 μl/vial
Spry4 Overview
Facts about Protein sprouty homolog 4.
Protein sprouty homolog 4 (Spry4)
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the creation of GTP-Ras (By similarity).
Inhibits Ras-independent, but not Ras- dependent, activation of RAF1 (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Spry4 |
| Uniprot: | Q9WTP2 |
| Entrez: | 24066 |
Family
| Belongs to: |
|---|
| sprouty family |
Alternative Names
protein sprouty homolog 4; sprouty homolog 4 (Drosophila); SPRY4; spry-4
Molecular Weight
Mass (kDA):
32.523 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 18 B3|18 20.5 cM |
| Sequence: | 18; |
Tissue Specificity
Expressed in the embryo and adult tissues including heart, brain, lung, kidney, and skeletal muscle.
Diseases
- Malignant Neoplasms
- Neoplasms
- Germ Cell Tumor
- Testicular Neoplasms
- Neoplasms, Germ Cell And Embryonal
- Testicular Germ Cell Tumor
- Malignant Neoplasm Of Testis
- Tumor Angiogenesis
- Cell Invasion
- Neoplasm Invasiveness
- Carcinogenesis
- Carcinoma
- Melanoma
Pathways
- Cell Proliferation
- Cell Growth
- Angiogenesis
- Cell Differentiation
- Regeneration
- Cell Migration
- Lung Morphogenesis
- Lung Development
- Cell Cycle
- Segmentation
- Pancreas Development
- Cell Development
- Endocytosis
PTMs
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Spry4
bosterbio.com/bosterbio-gene-info-cards/Spry4
References
PMID: 10330503 by de Maximy A.A., et al. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo.
PMID: 10498682 by Minowada G., et al. Vertebrate sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.