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- Table of Contents
SSTR1 Antibodies
AND SSTR1 ELISA kits, SSTR1 Proteins
Many biological assays use antibodies to detect SSTR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SSTR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SSTR1 antibodies...
Designing an IHC experiment for SSTR1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SSTR1 IHC GuideSSTR1 Infographic by Boster Bio
All SSTR1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1693
100 μg/vial
Cat # PA1693
100 μg/vial
Human
IF, ICC, WB
$370
Cat # M04717
100 μl/vial
Cat # M04717
100 μl/vial
Human
$628
Cat # LS006751
20 µg, 100 µg
Cat # LS006751
20 µg, 100 µg
SSTR1 Overview
Facts about Somatostatin receptor type 1.
Somatostatin receptor type 1 (SSTR1)
Receptor for somatostatin with greater affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SSTR1 |
| Uniprot: | P30872 |
| Entrez: | 6751 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
G-protein coupled receptor; Somatostatin R1; somatostatin receptor 1; somatostatin receptor type 1; SomatostatinR1; SRIF-2; SS1R; SS-1-R; SS1-R; SSR1; SSTR1
Molecular Weight
Mass (kDA):
42.686 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q21.1 |
| Sequence: | 14; NC_000014.9 (38207904..38213067) |
Tissue Specificity
Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Neoplasms
- Pituitary Diseases
- Malignant Neoplasms
- Adenoma
- Pituitary Neoplasms
- Carcinoma
- Pertussis
- Neuroendocrine Tumors
- Pituitary Adenoma
- Nervousness
- Acromegaly
- Malignant Neoplasm Of Prostate
Pathways
- Secretion
- Cell Proliferation
- Localization
- Hormone Secretion
- Cell Growth
- Insulin Secretion
- Reverse Transcription
- Growth Hormone Secretion
- Transport
- Glucagon Secretion
- Glucose Homeostasis
- Cell Division
- Exocytosis
PTMs
- Phosphorylation
- Demethylation
- Dephosphorylation
Research Areas
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- GPCR
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SSTR1
bosterbio.com/bosterbio-gene-info-cards/SSTR1
References
PMID: 1346068 by Yamada Y., et al. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.
PMID: 10734105 by Schwaerzler A., et al. Interaction of the somatostatin receptor subtype 1 with the human homolog of the Shk1 kinase-binding protein from yeast.
1 Publications of Boster SSTR1 Antibodies & ELISA Kits
- PubMed ID: 23991955, Guo Rs, Shi Pd, Zhou J, Chen Yy. Asian Pac J Cancer Prev. 2013;14(7):4071-5. Som...
*More publications can be found for each product on its corresponding product page