Anti-Somatostatin Receptor 1/SSTR1 Antibody
Rabbit IgG polyclonal antibody for Somatostatin receptor type 1(SSTR1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Cited in 1 publication(s).
Anti-Somatostatin Receptor 1/SSTR1 Antibody Info At A Glance
|Reactivity:||Human, Mouse, Rat|
|Product Name||Anti-Somatostatin Receptor 1/SSTR1 Antibody
See all Somatostatin R1/SSTR1 primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for SOMATOSTATIN RECEPTOR 1/SSTR1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. SOMATOSTATIN RECEPTOR 1/SSTR1 information: Molecular Weight: 42686 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein; Tissue Specificity: Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.|
|Cite This Product||Anti-Somatostatin Receptor 1/SSTR1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1693)|
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|Anti-Somatostatin Receptor 1/SSTR1 Antibody may replace the following items: sc 25675|sc 11604|sc 11603.|
|Reactivity/Species||Human, Mouse, Rat|
*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin Receptor 1(361-381aa RAYSVEDFQPENLESGGVFRN), identical to the related rat and mouse sequences.|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For SSTR1 (Source: Uniprot.org, NCBI)
|NCBI Gene Id||6751|
|Species Of This Entry||Human|
|Protein Name||Somatostatin receptor type 1|
|Superfamily||G-protein coupled receptor 1 family|
|Alternative Names||Somatostatin R1/SSTR1|G-protein coupled receptor; Somatostatin R1; somatostatin receptor 1; somatostatin receptor type 1; SomatostatinR1; SRIF-2; SS1R; SS-1-R; SS1-R; SSR1; SSTR1|
|Post Tranlational Modifications||Phosphorylation; Demethylation; Dephosphorylation; Methylation; Biotinylation; Reduction; Glycosylation|
|Subcellular Localization||Cell membrane; Multi-pass membrane protein.|
|Gene Location||14q21.1, on Chromasome 14, gene sequence: NC_000014.9 (38207904..38213067)|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For SSTR1 (Source: Uniprot.org, NCBI)
|Protein Function||Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.|
|Tissue Specificity||Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.|
|Research Areas||Breast Cancer; Cancer; Cell Cycle and Replication; GPCR; Neuronal Cell Markers; Neuroscience; Neurotransmission|
|Related Diseases||Neoplasms; Pituitary Diseases; Malignant Neoplasms; Adenoma; Pituitary Neoplasms; Carcinoma; Pertussis; Neuroendocrine Tumors; Pituitary Adenoma; Nervousness; Acromegaly; Malignant Neoplasm Of Prostate; Malignant Paraganglionic Neoplasm; Prostatic Neoplasms; Neoplasm Metastasis; Carcinoid Tumor; Malignant Neoplasm Of Breast; Mammary Neoplasms; Pancreatic Neoplasm|
|Related Pathways||Secretion; Cell Proliferation; Localization; Hormone Secretion; Cell Growth; Insulin Secretion; Reverse Transcription; Growth Hormone Secretion; Transport; Glucagon Secretion; Glucose Homeostasis; Cell Division; Exocytosis; Regulation Of Growth; Cell Cycle Arrest; Cell Cycle; Catecholamine Secretion; Gastric Acid Secretion; Regulation Of Growth Hormone Secretion; Dna Methylation|
|Background||SSTR1(Somatostatin receptor type 1) is a protein that in humans is encoded by the SSTR1 gene. The SSTR1 gene is mapped to chromosome 14. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.|
|Scientific References||PMID: 1346068 by Yamada Y., et al. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.|
PMID: 10734105 by Schwaerzler A., et al. Interaction of the somatostatin receptor subtype 1 with the human homolog of the Shk1 kinase-binding protein from yeast.
Our Boster Quality Guarantee for Anti-Somatostatin Receptor 1/SSTR1 Antibody covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 0.5-1μg/ml, Rat, Human, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Rat, Human, Mouse
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
All lanes: Anti SSTR1 (PA1693) at 0.5ug/ml
WB: Rat Intestine Tissue Lysate at 50ug
Predicted bind size: 43KD
Observed bind size: 60KD
IHC(P): Rat Intestine Tissue
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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