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- Table of Contents
Facts about Syntaxin-binding protein 2.
Regulates cytotoxic granule exocytosis in natural killer (NK) cells. .
Human | |
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Gene Name: | STXBP2 |
Uniprot: | Q15833 |
Entrez: | 6813 |
Belongs to: |
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STXBP/unc-18/SEC1 family |
FHL5; Hunc18b; MUNC18-2; Protein unc-18 homolog 2; Protein unc-18 homolog B; STXBP2; syntaxin binding protein 2; syntaxin-binding protein 2; SyntaxinBP2; Syntaxin-BP2; Unc18-2; UNC18B; unc-18B; UNC18Bpp10122
Mass (kDA):
66.453 kDA
Human | |
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Location: | 19p13.2 |
Sequence: | 19; NC_000019.10 (7637110..7647873) |
Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
In this article we discuss the Anti-Phospho-Munc-18 (Ser513) STXBP2 Marker. We will also discuss the use of high-affinity primary antibodies and the history of Steven Boster. These results are applicable to all scientists around the world. This is a comprehensive review of the STXBP2 marker and its best uses. If you have any questions, please contact us at [email protected].
Anti-Phospho-Munc (18 (Ser513) STXBP2Marker at Boster Bio is a monoclonal antibody that reacts with Rat and Mouse and is available in several formats. The Boster Bio Anti-Phospho-Munc-18 (Ser513) Marker is a part of Boster's Picoband(tm) catalog, and is tested to react with Human, Mouse, Rat, and STXBP1 protein.
We performed a series of experiments with human antibodies to identify high-affinity primary antibodies using the STXB2 marker. The result of these experiments was the generation of IgM that bound insulin to a specific target. These results were confirmed by indirect IF. The STXB2 marker is an innate immune cell surface protein. The STXB2 protein is expressed on the surface of many cells.
The specific antibody has to have an affinity constant of at least 0.15 to recognize the epitope in the fixed tissue. This constant is unknown, and the procedure may require harsh or denaturing methods to obtain the antibody. However, this is often the only way to create high-affinity primary antibodies. Nonetheless, this is a promising approach for the discovery of new biological targets. In addition, high-affinity primary antibodies using the STXBP2 marker have been successfully developed for use in a variety of applications.
These studies suggest that the STXBP2 marker is an effective tool for detecting the epitopes of autoimmune diseases. The STXB2 marker is also an efficient tool to identify circulating antibodies. The corresponding antibodies are produced in human serum, mouse serum, and reagents. They are highly specific and characterized for use in a variety of applications. In contrast to conventional primary antibodies, this one identifies the epitopes of target cells.
The development of high-affinity primary antibodies using the STXB2 marker has been possible since 2009. It allows researchers to detect antigens in a variety of settings and for a large range of applications. High-affinity antibodies generated from the STXB2 marker are useful in multiple reaction monitoring-mass spectrometry assays. The STXB2 marker provides a reliable, accurate way to detect peptide-based antigens.
The STXB2 marker was first identified by Professor Nobuo Sakaguchi in 1998. It plays an important role in the reconstruction of antibody genes. High-affinity primary antibodies generated in transgenic mice expressing the STXB2 marker are associated with the MCM3 gene, which is essential for DNA replication. These results support the theory that soluble monovalent antigens interfere with the development of B-lymphocytes.
The STXB2 marker can be used to identify autoreactive IgM and IgD in murine sera. Although the two molecules are similar, their structures are different. This means that if one is producing an antibody to an anti-IgD marker, it may not be a good match. The STXB2 marker can be useful in other cases, but it has limited utility in the current context.
Using the STXB2 marker allows researchers to determine if a specific antibody is highly reactive to the target antigen. Aside from identifying antibodies that have high affinity for a target, they can also help with the detection of other antibodies. High-affinity primary antibodies can be useful for diagnostics and screening tests. High-affinity primary antibodies are useful in the detection of various pathological processes and autoimmune diseases.
The history of Steve Boster includes many significant milestones and public records. These details include current and previous addresses, known relatives, and mobile phone numbers. You can also browse Steve's history by state or age. By entering Steve's name into the search box, you can see a detailed profile of Steve. To learn more, continue reading about Steve Boster. He has left a lasting legacy. The family will forever miss Steve.
Steve Boster was born on September 8, 1950 in Joliet, IL and passed away on June 6, 2022 in Madison, WI. His parents were James and Evelyn Meier Boster. He was a manager in retail sales for many years, and a U.S. Army veteran. Steve was a member of Concordia Hall in Staunton, Virginia, and is survived by his two daughters, Natosha Peck and Crystal Boster. His siblings include Sandra Blanton and Jack Boster, along with Lisa Milton. Steven's nieces and nephews also survive him.
PMID: 8921365 by Ziegler S.F., et al. Molecular characterization of a nonneuronal human UNC18 homolog.
PMID: 19804848 by zur Stadt U., et al. Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.