TACC2 Antibodies

AND TACC2 ELISA kits, TACC2 Proteins

Many biological assays use antibodies to detect TACC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TACC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TACC2 antibodies...

We validate the specificity of these antibodies to TACC2 by testing them on tissues known to express TACC2 positively and negatively. Browse below to find the TACC2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TACC2 Infographic by Boster Bio

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Anti-TACC2 Mouse Monoclonal Antibody [Clone ID: OTI3C4]

Human recombinant protein fragment corresponding to amino acids 727-1026 of human TACC2 (NP_008928) produced in E

Human

IHC, WB

$523
Cat # M05346
100 µl

TACC2 Overview

Facts about Transforming acidic coiled-coil-containing protein 2.

Transforming acidic coiled-coil-containing protein 2 (TACC2)

Plays a role in the microtubule-dependent coupling of the nucleus along with the centrosome. Involved in the processes that govern centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity).

May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein.

Gene Information

Human
Gene Name:	TACC2
Uniprot:	O95359
Entrez:	10579

Family

Belongs to:

TACC family

Alternative Names

anti zuai-1; AZU-1ECTACC; EC 2.4.2.10; EC 4.3.2.1; EC 6.3.5.2; transforming acidic coiled-coil-containing protein 2; transforming, acidic coiled-coil containing protein 2; Zuai-1

Molecular Weight

Mass (kDA):
309.427 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (121989163..122254542)

Tissue Specificity

Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Prostatic Neoplasms
Carcinogenesis
Multiple Myeloma
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Neoplasm Recurrence, Local
Leukemia
Neoplasm Metastasis
Cyclic Neutropenia

Non-neoplastic Disorder
Tumor Progression
Aneuploidy
Severe Congenital Neutropenia
Neoplasm, Residual
Patient Dependence On
Esophageal Neoplasms

Pathways

Cell Cycle
Cell Division
Chromatin Remodeling
Mitosis
Cell Growth
Cell Proliferation
Localization
Anaphase
Translation
Tissue Morphogenesis
Neutrophil Differentiation
M Phase
Histone Modification

Metaphase
Chromosome Segregation
Cytokinesis
Methylation
Oocyte Development
Rna Processing
Pathogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TACC2

References

PMID: 10749935 by Chen H.-M., et al. AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression.

PMID: 11121038 by Gergely F., et al. The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.