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- Table of Contents
Substance-P receptor Antibodies
AND TACR1 ELISA kits, Substance-P receptor Proteins
Many biological assays use antibodies to detect Substance-P receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Substance-P receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Substance-P receptor antibodies...
Designing a Western blot for Substance-P receptor? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TACR1 Western Blot GuideDesigning an IHC experiment for Substance-P receptor? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TACR1 IHC GuideTACR1 Infographic by Boster Bio
All TACR1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$370
Cat # PA1684
100 μg/vial
Cat # PA1684
100 μg/vial
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M01006
100 μl
Cat # M01006
100 μl
Human
$628
Cat # LS006869
20 µg, 100 µg
Cat # LS006869
20 µg, 100 µg
TACR1 Overview
Facts about Substance-P receptor.
Substance-P receptor (TACR1)
This is a receptor for the tachykinin neuropeptide substance P. It's probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TACR1 |
| Uniprot: | P25103 |
| Entrez: | 6869 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
NK1R; NK-1R; NK1Rneurokinin 1 receptor; NKIR; SPR; SPRsubstance-P receptor; TAC1R; TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); tachykinin receptor 1NK-1 receptor; TACR1
Molecular Weight
Mass (kDA):
46.251 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p12 |
| Sequence: | 2; NC_000002.12 (75046463..75199520, complement) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Pain
- Anxiety Disorders
- Malnutrition
- Malignant Neoplasms
- Depressive Disorder
- Inflammation
- Attention Deficit Hyperactivity Disorder
- Neoplasms
- Cancer Patients And Suicide And Depression
- Lung Injury
- Nausea And Vomiting
Interacting Proteins
- TAC1
Pathways
- Localization
- Cell Adhesion
- Relaxation Of Vascular Smooth Muscle
- Smooth Muscle Contraction
- Translation
- Sperm Motility
- Immune Response
- Muscle Contraction
PTMs
Research Areas
- GPCR
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TACR1
bosterbio.com/bosterbio-gene-info-cards/TACR1
References
PMID: 1718267 by Takeda Y., et al. Molecular cloning, structural characterization and functional expression of the human substance P receptor.
PMID: 1659396 by Hopkins B., et al. Isolation and characterisation of the human lung NK-1 receptor cDNA.