Toll-like receptor 7 (TLR7)

Key part of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to germs.

TLR7 is a nucleotide-sensing TLR that's triggered by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).