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Toll-like receptor 7 Antibodies
AND TLR7 ELISA kits, Toll-like receptor 7 Proteins
Many biological assays use antibodies to detect Toll-like receptor 7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 7 antibodies...
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TLR7 Infographic by Boster Bio
All TLR7 Products
Product
Figures
Specificity
Applications
Price
Anti-TLR7 Antibody Picoband®
1 Citations 16 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9452
100 μg/vial
Cat # PB9452
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1733
100 μg/vial
Cat # PA1733
100 μg/vial
Cynomolgus monkey, Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00376-1
100 μg
Cat # M00376-1
100 μg
TLR7 Overview
Facts about Toll-like receptor 7.
Toll-like receptor 7 (TLR7)
Key part of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to germs.
TLR7 is a nucleotide-sensing TLR that's triggered by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | TLR7 |
| Uniprot: | Q9NYK1 |
| Entrez: | 51284 |
Family
| Belongs to: |
|---|
| Toll-like receptor family |
Alternative Names
TLR7; toll-like receptor 7
Molecular Weight
Mass (kDA):
120.922 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.2 |
| Sequence: | X; NC_000023.11 (12867072..12890361) |
Tissue Specificity
Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Diseases
- Virus Diseases
- Inflammation
- Infective Disorder
- Innate Immune Response
- Autoimmune Reaction
- Malignant Neoplasms
- Neoplasms
- Lupus Erythematosus, Systemic
- Autoimmune Diseases
- Influenza
- Autoimmunity
- Hiv Infections
- Hepatitis
Pathways
- Immune Response
- Secretion
- Cytokine Production
- Pathogenesis
- Innate Immune Response
- Cell Activation
- Inflammatory Response
- Cell Proliferation
- Viral Replication
- Localization
- Cytokine Secretion
- Adaptive Immune Response
- Rna Interference
PTMs
- Phosphorylation
- Methylation
- Phosphorothioation
- Cleavage
- Ubiquitination
- Glycosylation
Research Areas
- Cytokine Research
- Immunology
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR7
bosterbio.com/bosterbio-gene-info-cards/TLR7
References
PMID: 11022119 by Du X., et al. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution.
PMID: 11022120 by Chuang T.-H., et al. Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.
1 Publications of Boster Toll-like receptor 7 Antibodies & ELISA Kits
- PubMed ID: 29561265, Esancy K, Condon L, Feng J, Kimball C, Curtright A, Dhaka A. Elife. 2018 Mar 21;...
*More publications can be found for each product on its corresponding product page