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- Table of Contents
Toll-like receptor 7 Antibodies
AND TLR7 ELISA kits, Toll-like receptor 7 Proteins
Many biological assays use antibodies to detect Toll-like receptor 7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 7 antibodies...
Designing a Western blot for Toll-like receptor 7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TLR7 Western Blot GuideTLR7 Infographic by Boster Bio
All TLR7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9452
100 μg/vial
Cat # PB9452
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1733
100 μg/vial
Cat # PA1733
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00376-1
100 μg
Cat # M00376-1
100 μg
Functional Assay
$7280
Cat # RC1029
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1029
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
TLR7 Overview
Facts about Toll-like receptor 7.
Toll-like receptor 7 (TLR7)
Key part of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to germs.
TLR7 is a nucleotide-sensing TLR that's triggered by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | TLR7 |
| Uniprot: | Q9NYK1 |
| Entrez: | 51284 |
Family
| Belongs to: |
|---|
| Toll-like receptor family |
Alternative Names
TLR7; toll-like receptor 7
Molecular Weight
Mass (kDA):
120.922 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.2 |
| Sequence: | X; NC_000023.11 (12867072..12890361) |
Tissue Specificity
Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Diseases
- Virus Diseases
- Inflammation
- Infective Disorder
- Innate Immune Response
- Autoimmune Reaction
- Malignant Neoplasms
- Neoplasms
- Lupus Erythematosus, Systemic
- Autoimmune Diseases
- Influenza
- Autoimmunity
- Hiv Infections
- Hepatitis
Pathways
- Immune Response
- Secretion
- Cytokine Production
- Pathogenesis
- Innate Immune Response
- Cell Activation
- Inflammatory Response
- Cell Proliferation
- Viral Replication
- Localization
- Cytokine Secretion
- Adaptive Immune Response
- Rna Interference
PTMs
- Phosphorylation
- Methylation
- Phosphorothioation
- Cleavage
- Ubiquitination
- Glycosylation
Research Areas
- Cytokine Research
- Immunology
- Innate Immunity
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR7
bosterbio.com/bosterbio-gene-info-cards/TLR7
References
PMID: 11022119 by Du X., et al. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution.
PMID: 11022120 by Chuang T.-H., et al. Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.
1 Publications of Boster Toll-like receptor 7 Antibodies & ELISA Kits
- PubMed ID: 29561265, Esancy K, Condon L, Feng J, Kimball C, Curtright A, Dhaka A. Elife. 2018 Mar 21;...
*More publications can be found for each product on its corresponding product page