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- Table of Contents
Toll-interacting protein Antibodies
AND TOLLIP ELISA kits, Toll-interacting protein Proteins
Many biological assays use antibodies to detect Toll-interacting protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-interacting protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-interacting protein antibodies...
Designing an IHC experiment for Toll-interacting protein? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TOLLIP IHC GuideTOLLIP Infographic by Boster Bio
All TOLLIP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # PA2005
100 μg/vial
Cat # PA2005
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02039-1
100 μg/vial
Cat # A02039-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$481
Cat # A02039
0.1 mg
Cat # A02039
0.1 mg
TOLLIP Overview
Facts about Toll-interacting protein.
Toll-interacting protein (TOLLIP)
Component of the signaling pathway of IL-1 and Toll-like receptors.
Inhibits cell activation by microbial products.Recruits IRAK1 into the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856).
Gene Information
| Human | |
|---|---|
| Gene Name: | TOLLIP |
| Uniprot: | Q9H0E2 |
| Entrez: | 54472 |
Family
| Belongs to: |
|---|
| tollip family |
Alternative Names
adapter protein; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; Tollip
Molecular Weight
Mass (kDA):
30.282 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.5 |
| Sequence: | 11; NC_000011.10 (1274368..1309632, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Inflammation
- Innate Immune Response
- Inflammatory Response
- Malignant Neoplasms
- Asthma
- Infective Disorder
- Cell Invasion
- Systemic Infection
- Tuberculosis
- Bacterial Infections
- Autoimmune Diseases
- Colitis
- Autoimmune Reaction
Interacting Proteins
- ACTN2
- CSTF1
- DAB1
- DAZAP2
- DZIP3
- EIF2AK2
- IRAK2
- MAP1LC3A
- PEG10
- RBPMS
Pathways
- Immune Response
- Inflammatory Response
- Innate Immune Response
- Pathogenesis
- Secretion
- Localization
- Cytokine Secretion
- Reverse Transcription
- Cell Activation
- Adaptive Immune Response
- Toll-like Receptor Signaling Pathway
- Endocytosis
- Cytokine Production
PTMs
- Phosphorylation
- Ubiquitination
- Sumoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TOLLIP
bosterbio.com/bosterbio-gene-info-cards/TOLLIP
References
PMID: 10854325 by Burns K., et al. Tollip, a new component of the IL-1R1 pathway, links IRAK to the IL-1 receptor.
PMID: 11751856 by Zhang G., et al. Negative regulation of Toll-like receptor-mediated signaling by Tollip.
1 Publications of Boster Toll-interacting protein Antibodies & ELISA Kits
- PubMed ID: 25269519, Liu Mw, Wang Yh, Qian Cy, Li H. Int J Mol Med. 2014 Dec;34(6):1492-504. Doi: 10....
*More publications can be found for each product on its corresponding product page