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- Table of Contents
Tribbles homolog 2 Antibodies
AND TRIB2 ELISA kits, Tribbles homolog 2 Proteins
Many biological assays use antibodies to detect Tribbles homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tribbles homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tribbles homolog 2 antibodies...
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TRIB2 Infographic by Boster Bio
All TRIB2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IF, IHC, WB
$523
Cat # M06479
100 µl
Cat # M06479
100 µl
TRIB2 Overview
Facts about Tribbles homolog 2.
Tribbles homolog 2 (TRIB2)
Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TRIB2 |
| Uniprot: | Q92519 |
| Entrez: | 28951 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
C5FW; FLJ57420; GS3955; TRB-2; TRB2tribbles homolog 2; tribbles homolog 2 (Drosophila)
Molecular Weight
Mass (kDA):
38.801 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p24.3 |
| Sequence: | 2; NC_000002.12 (12716872..12742734) |
Tissue Specificity
Highly expressed in peripheral blood leukocytes.
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton. May associate with the cytoskeleton.
Diseases
- Leukemia
- Malignant Neoplasms
- Myeloid Leukemia
- Neoplasms
- Leukemia, Myelocytic, Acute
- Cell Transformation, Neoplastic
- Narcolepsy
- Leukemogenesis
- Autoimmune Reaction
- Cataplexy
- Autoimmunity
- Excessive Daytime Somnolence
- Precursor T-cell Lymphoblastic Leukemia-lymphoma
Pathways
- Cell Proliferation
- Pathogenesis
- Localization
- Gene Silencing
- Photomorphogenesis
- Mitosis
- Dna Repair
- Ovulation
- Cell Cycle
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRIB2
bosterbio.com/bosterbio-gene-info-cards/TRIB2
References
PMID: 15299019 by Kiss-Toth E., et al. Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
PMID: 15950723 by Zhang Y., et al. Identification of tribbles homolog 2 as an autoantigen in autoimmune uveitis by phage display.