TPH2 Antibodies

AND TPH2 ELISA kits, TPH2 Proteins

Many biological assays use antibodies to detect TPH2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TPH2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TPH2 antibodies...

We validate the specificity of these antibodies to TPH2 by testing them on tissues known to express TPH2 positively and negatively. Browse below to find the TPH2 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TPH2 Infographic by Boster Bio

All TPH2 Products

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Specificity

Applications

Price

TPH2 Colorimetric Cell-Based ELISA Kit

Western blot analysis of the lysates from HUVECcells using TPH2 antibody

Human, Mouse, Rat

ELISA

$480
Cat # EKC1573
1 kit, containing one 96-well plate and all necessary reagents

Anti-Tryptophan 5-hydroxylase 2 TPH2 Antibody

Immunofluorescence analysis of A549 cell using TPH2 antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A01643
100ul

Anti-Phospho-TPH2 (S19) Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A01643S19
100ul

Tryptophan 5 hydroxylase 2 (TPH2) (NM_173353) Human Recombinant Protein

Coomassie blue staining of purified TPH2 protein

$1062
Cat # PROTQ8IWU9
20 µg

Anti-TPH2 Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # A01643-1
100 μl/vial

Anti-TPH2 Rabbit Monoclonal Antibody

Western blot analysis of TPH2 using anti-TPH2 antibody (M01643)

IHC analysis of TPH2 using anti-TPH2 antibody (M01643)

IF, IHC, WB

$370
Cat # M01643
100 μl

Anti-Zebrafish TPH2 Antibody

IHC analysis of TPH2 using anti-TPH2 antibody (AZA0A8M1P7E6)

Zebrafish

IHC

$470
Cat # AZA0A8M1P7E6
100 μg/vial

Anti-TPH2 Antibody (Monoclonal, 35T28)

Mouse, Rat

IP, IHC, WB

$370
Cat # M01643-1
100 μl/vial

TPH2 Overview

Facts about Tryptophan 5-hydroxylase 2.

TPH2 3D structure. Source: alphafold

Tryptophan 5-hydroxylase 2 (TPH2)

Gene Information

Human
Gene Name:	TPH2
Uniprot:	Q8IWU9
Entrez:	121278

Family

Belongs to:

biopterin-dependent aromatic amino acid hydroxylase family

Alternative Names

ADHD7; EC 1.14.16; EC 1.14.16.4; FLJ37295; MGC138872; Neuronal tryptophan hydroxylase; NTPH; NTPHMGC138871; TPH2; tryptophan 5-hydroxylase 2; Tryptophan 5-monooxygenase 2; Tryptophan Hydroxylase 2

Molecular Weight

Mass (kDA):
56.057 kDA

Genomic Context


Human

Location:	12q21.1
Sequence:	12; NC_000012.12 (71938845..72032440)

Tissue Specificity

Brain specific.

Diseases

Depressive Disorder
Major Depressive Disorder
Mental Disorders
Anxiety Disorders
Mood Disorders
Nervousness
Cancer Patients And Suicide And Depression
Bipolar Disorder
Schizophrenia
Attention Deficit Hyperactivity Disorder
Stress, Psychological

Dysequilibrium Syndrome
Autistic Disorder
Depressive Symptom
Obsessive-compulsive Disorder
Malnutrition
Physiological Stress

Pathways

Pathogenesis
Brain Development
Transport
Secretion
Innervation
Excretion
Neurogenesis
Localization
Swimming
Cognition
Immune Response
Adult Behavior

Regulation Of Behavior
Regulation Of Gene Expression
Response To Methylphenidate
Mrna Processing
Circadian Rhythm
Locomotion
Sex Differentiation

PTMs

Phosphorylation
Hydroxylation
Cleavage

Decarboxylation
Oxidation
Methylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TPH2

References

PMID: 12511643 by Walther D.J., et al. Synthesis of serotonin by a second tryptophan hydroxylase isoform.

PMID: 17905754 by Cichon S., et al. Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder.