UGGT1 Antibodies

AND UGGT1 ELISA kits, UGGT1 Proteins

Many biological assays use antibodies to detect UGGT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGGT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGGT1 antibodies...

We validate the specificity of these antibodies to UGGT1 by testing them on tissues known to express UGGT1 positively and negatively. Browse below to find the UGGT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGGT1 Infographic by Boster Bio

All UGGT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-UGGT1 Antibody

Western blot analysis of extracts of various cell lines, using UGGT1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A10212-1
100ul

Anti-UGGT/UGT1/UGGT1 Antibody Picoband®

Western blot analysis of UGGT/UGT1/UGGT1 using anti-UGGT/UGT1/UGGT1 antibody (A10212-2)

Human

ELISA, WB

$370
Cat # A10212-2
100 μg/vial

UGGT (UGGT1) (NM_020120) Human Over-expression Lysate

Human

$960
Cat # LS056886
20 µg, 100 µg

UGGT1 Overview

Facts about UDP-glucose:glycoprotein glucosyltransferase 1.

UGGT1 3D structure. Source: alphafold

UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1)

Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans close to the misfolded area of the protein, thus providing quality control for protein folding in the endoplasmic reticulum.

Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. .

Gene Information

Human
Gene Name:	UGGT1
Uniprot:	Q9NYU2
Entrez:	56886

Family

Belongs to:

glycosyltransferase 8 family

Alternative Names

FLJ21763; GT; HUGT1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose glycoprotein glucosyltransferase 1; UGCGL1; UGGT; UGT1; UGTR

Molecular Weight

Mass (kDA):
177.19 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (128091184..128195677)

Tissue Specificity

Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.

Subcellular Localizations

Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.

Diseases

Diabetes Mellitus, Non-insulin-dependent
Diabetes Mellitus

Pathways

Insulin Secretion
Secretion

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGGT1

References

PMID: 10694380 by Arnold S.M., et al. Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.

PMID: 23349634 by Cloutier P., et al. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.