Ugt1a1 Antibodies

AND Ugt1a1 ELISA kits, Ugt1a1 Proteins

Many biological assays use antibodies to detect Ugt1a1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ugt1a1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ugt1a1 antibodies...

We validate the specificity of these antibodies to Ugt1a1 by testing them on tissues known to express Ugt1a1 positively and negatively. Browse below to find the Ugt1a1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ugt1a1 Infographic by Boster Bio

All Ugt1a1 Products

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Anti-UGT1A1 Antibody Picoband®

3 Citations 5 Q&As

Western blot analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1)

IHC analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1)

IF analysis of UGT1A1 using anti-UGT1A1 antibody (A01865-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01865-1
100 μg/vial

Human Glucuronosyltransferase 1A1/UGT1A1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP22309
Starting from 20ug

Anti-Ugt1a1 Antibody Picoband®

1 Citations

Western blot analysis of Ugt1a1 using anti-Ugt1a1 antibody (A01865-2)

Flow Cytometry analysis of ANA-1 cells using anti-Ugt1a1 antibody (A01865-2)

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01865-2
100 μg/vial

Ugt1a1 Overview

Facts about UDP-glucuronosyltransferase 1-1.

UDP-glucuronosyltransferase 1-1 (Ugt1a1)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Glucuronates opioids and bilirubin.

Gene Information

Rat
Gene Name:	Ugt1a1
Uniprot:	Q64550
Entrez:	24861

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

bilirubin UDP-glucuronosyltransferase 1-1; bilirubin UDP-glucuronosyltransferase isozyme 1; Bilirubin-specific UDPGT isozyme 1; GNT1; GNT1EC 2.4.1.17; HUG-BR1; UDP glucuronosyltransferase 1 family, polypeptide A1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDPGT 1-1; UDPGT; UG-BR1; UGT1; UGT1*1; UGT1.1; UGT1-01; UGT1A; UGT-1A; UGT1A1; UGT1AUDPGT 1-1; UGT1BILIQTL1

Molecular Weight

Mass (kDA):
59.663 kDA

Genomic Context


Rat

Location:	9q35
Sequence:	9;

Diseases

Malignant Neoplasms
Hyperbilirubinemia
Gilbert Disease (disorder)
Neoplasms
Colorectal Cancer
Unconjugated Hyperbilirubinemia
Crigler-najjar Syndrome
Icterus
Diarrhea
Colorectal Neoplasms
Malignant Neoplasm Of Breast
Hyperbilirubinemia, Neonatal

Colorectal Cancer Metastatic
Carcinoma
Neonatal Jaundice
Liver Carcinoma
Mammary Neoplasms
Liver Diseases
Aortic Aneurysm, Thoracic

Pathways

Conjugation
Excretion
Transport
Bilirubin Conjugation
Pathogenesis
Sulfation
Dna Repair
Reverse Transcription
Secretion
Gallstone Formation
Cell Cycle
Localization
Response To Irinotecan

Cell Proliferation
Methylation
Dna Methylation
Aging
Immune Response
Acyl Glucuronidation
Drug Resistance

PTMs

Phosphorylation
Hydroxylation
Oxidation
Acetylation
Demethylation
Methylation
Cleavage

Carboxylation
Reduction
Deamination
Deiodination
Dephosphorylation
Glycosylation
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ugt1a1

References

PMID: 7603447 by Coffman B.L., et al. Cloning and stable expression of a cDNA encoding a rat liver UDP- glucuronosyltransferase (UDP-glucuronosyltransferase 1.1) that catalyzes the glucuronidation of opioids and bilirubin.

PMID: 7608130 by Emi Y., et al. Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex.