Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X)

May thus play an important regulatory function at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Especially hydrolyzes'Lys-48'-,'Lys- 29'- and'Lys-33'-linked polyubiquitins chains.

Essential component of TGF-beta/BMP signaling cascade. Especially deubiquitinates monoubiquitinated SMAD4, opposing the action of E3 ubiquitin-protein ligase TRIM33.