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- Table of Contents
USP9X Antibodies
AND USP9X ELISA kits, USP9X Proteins
Many biological assays use antibodies to detect USP9X, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP9X in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP9X antibodies...
Designing a Western blot for USP9X? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the USP9X Western Blot GuideDesigning an IHC experiment for USP9X? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the USP9X IHC GuideUSP9X Infographic by Boster Bio
All USP9X Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02594-1
100 μg/vial
Cat # A02594-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02594-1
100 μl/vial
Cat # M02594-1
100 μl/vial
USP9X Overview
Facts about Probable ubiquitin carboxyl-terminal hydrolase FAF-X.
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X)
May thus play an important regulatory function at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Especially hydrolyzes'Lys-48'-,'Lys- 29'- and'Lys-33'-linked polyubiquitins chains.
Essential component of TGF-beta/BMP signaling cascade. Especially deubiquitinates monoubiquitinated SMAD4, opposing the action of E3 ubiquitin-protein ligase TRIM33.
Gene Information
| Human | |
|---|---|
| Gene Name: | USP9X |
| Uniprot: | Q93008 |
| Entrez: | 8239 |
Family
| Belongs to: |
|---|
| peptidase C19 family |
Alternative Names
Deubiquitinating enzyme FAF-X; DFFRX; DFFRXubiquitin specific protease 9, X-linked (fat facets-like, Drosophila); Drosophila fat facets related, X-linked; EC 3.1.2.15; EC 3.4.19.12; FAF; FAM; Fat facets in mammals; fat facets protein related, X-linked; Fat facets protein-related, X-linked; hFAM; probable ubiquitin carboxyl-terminal hydrolase FAF-X; ubiquitin specific peptidase 9, X-linked (fat facets-like, Drosophila); ubiquitin specific peptidase 9, X-linked; ubiquitin thioesterase FAF-X; Ubiquitin thiolesterase FAF-X; ubiquitin-specific processing protease FAF-X; Ubiquitin-specific protease
Molecular Weight
Mass (kDA):
292.28 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp11.4 |
| Sequence: | X; NC_000023.11 (41085420..41236579) |
Tissue Specificity
Widely expressed in embryonic and adult tissues.
Subcellular Localizations
Cytoplasm. Cell projection, growth cone.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Leukemia
- Myeloid Leukemia
- Parkinson Disease
- Malignant Neoplasm Of Pancreas
- Turner Syndrome
- Myeloid Leukemia, Chronic
- Carcinoma
- Mammary Neoplasms
- Adenocarcinoma
- Pancreatic Ductal Adenocarcinoma
Interacting Proteins
- HTT
- MCL1
- SMAD4
Pathways
- Cell Death
- Cell Differentiation
- Autophagy
- Cell Adhesion
- Spermatogenesis
- Oogenesis
- Localization
- Brain Development
- Eye Development
- Cell Growth
- Transport
- Muscle Cell Differentiation
- Fertilization
PTMs
- Ubiquitination
- Phosphorylation
Research Areas
- Apoptosis
- Autophagy
- Cancer
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP9X
bosterbio.com/bosterbio-gene-info-cards/USP9X
References
PMID: 8922996 by Jones M.H., et al. The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.
PMID: 16322459 by Vong Q.P., et al. Chromosome alignment and segregation regulated by ubiquitination of survivin.