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- Table of Contents
VAMP4 Antibodies
AND VAMP4 ELISA kits, VAMP4 Proteins
Many biological assays use antibodies to detect VAMP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VAMP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VAMP4 antibodies...
Designing a Western blot for VAMP4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VAMP4 Western Blot GuideVAMP4 Infographic by Boster Bio
All VAMP4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05647-2
100 μg/vial
Cat # A05647-2
100 μg/vial
VAMP4 Overview
Facts about Vesicle-associated membrane protein 4.
Vesicle-associated membrane protein 4 (VAMP4)
Involved in the pathway that functions to eliminate an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a mark for this sorting pathway that's critical for remodeling the secretory response of granule.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | VAMP4 |
| Uniprot: | O75379 |
| Entrez: | 8674 |
Family
| Belongs to: |
|---|
| synaptobrevin family |
Alternative Names
VAMP24; VAMP-4; vesicle-associated membrane protein 4
Molecular Weight
Mass (kDA):
16.397 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q24.3 |
| Sequence: | 1; NC_000001.11 (171700160..171742844, complement) |
Subcellular Localizations
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Insulin Resistance
- Pituitary Diseases
- Pheochromocytoma
- Dysequilibrium Syndrome
- Bovine Anaplasmosis
- Male Infertility
- Tissue Adhesions
- Infertility
- Insulin Sensitivity
Interacting Proteins
- BCL2L13
- CCDC155
- SNAP29
- SNAP47
- STX4
- STX6
Pathways
- Transport
- Exocytosis
- Localization
- Secretory Pathway
- Membrane Fusion
- Secretion
- Vesicle Fusion
- Cell Migration
- Snare Complex Assembly
- Regulated Secretory Pathway
- Intracellular Transport
- Endocytosis
- Cell Adhesion
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Membrane Trafficking and Chaperones
- Membrane Vesicle Markers
- Neuronal Cell Markers
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAMP4
bosterbio.com/bosterbio-gene-info-cards/VAMP4
References
PMID: 9553086 by Advani R.J., et al. Seven novel mammalian SNARE proteins localize to distinct membrane compartments.
PMID: 28626000 by Zhang X., et al. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.