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- Table of Contents
VASP Antibodies
AND VASP ELISA kits, VASP Proteins
Many biological assays use antibodies to detect VASP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VASP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VASP antibodies...
Designing a Western blot for VASP? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VASP Western Blot GuideDesigning an IHC experiment for VASP? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the VASP IHC GuideVASP Infographic by Boster Bio
All VASP Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1874
96 wells/kit, with removable strips.
Cat # EK1874
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05352-2
100 μg/vial
Cat # A05352-2
100 μg/vial
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00303-3
20μL, 40μL, 100μL, 200μL
Cat # M00303-3
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2537
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2537
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2008
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2008
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1588
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1588
1 kit, containing one 96-well plate and all necessary reagents
VASP Overview
Facts about Vasodilator-stimulated phosphoprotein.
Vasodilator-stimulated phosphoprotein (VASP)
Ena/VASP proteins are actin-associated proteins involved in a selection of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation.
It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin- bound actin monomers on the barbed end of growing actin filaments.
Gene Information
| Human | |
|---|---|
| Gene Name: | VASP |
| Uniprot: | P50552 |
| Entrez: | 7408 |
Family
| Belongs to: |
|---|
| Ena/VASP family |
Alternative Names
vasodilator-stimulated phosphoprotein; VASP
Molecular Weight
Mass (kDA):
39.83 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.32 |
| Sequence: | 19; NC_000019.10 (45507459..45526989) |
Tissue Specificity
Highly expressed in platelets.
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with
Diseases
- Tissue Adhesions
- Acute Coronary Syndrome
- Thrombosis
- Malignant Neoplasms
- Neoplasms
- Protrusion
- Myocardial Infarction
- Coronary Artery Disease
- Cardiovascular Diseases
- Hemorrhage
- Cell Invasion
- Infarction
Interacting Proteins
- ABI2
- ABI3
- FGFR1OP
- NR4A1
- NSMAF
- RPS6KA1
- SCGB2A2
- TRIM9
- XIRP1
- ZYX
Pathways
- Platelet Aggregation
- Cell Motility
- Platelet Activation
- Localization
- Cell Migration
- Cell Adhesion
- Axon Guidance
- Cell-cell Adhesion
- Angiogenesis
- Cell Proliferation
- Pathogenesis
- Protein Phosphorylation
- Chemotaxis
PTMs
- Phosphorylation
- Dephosphorylation
- Nitration
- Cleavage
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VASP
bosterbio.com/bosterbio-gene-info-cards/VASP
References
PMID: 7828592 by Haffner C., et al. Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP.
PMID: 10087267 by Laurent V., et al. Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes.