VPS13B Antibodies

AND VPS13B ELISA kits, VPS13B Proteins

Many biological assays use antibodies to detect VPS13B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VPS13B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VPS13B antibodies...

We validate the specificity of these antibodies to VPS13B by testing them on tissues known to express VPS13B positively and negatively. Browse below to find the VPS13B antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VPS13B Infographic by Boster Bio

All VPS13B Products

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Product

Figures

Specificity

Applications

Price

Anti-COH1 VPS13B Antibody

Western blot analysis of COH1 in SK-N-SH cell lysate with COH1 antibody at (A) 1 and (B) 2 μg/mL

Immunofluorescence of COH1 in human brain tissue with COH1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, WB

$481
Cat # A04566
0.1 mg

VPS13B (NM_181661) Human Recombinant Protein

Coomassie blue staining of purified VPS13B protein

$1249
Cat # PROTQ7Z7G8
20 µg

Anti-VPS13B Mouse Monoclonal Antibody [Clone ID: OTI6F6]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY VPS13B (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M04566
100 µl

VPS13B (NM_181661) Human Over-expression Lysate

Human

$628
Cat # LS157680
20 µg, 100 µg

VPS13B Overview

Facts about Vacuolar protein sorting-associated protein 13B.

Vacuolar protein sorting-associated protein 13B (VPS13B)

May be involved in protein sorting in place Golgi membrane traffic. .

Gene Information

Human
Gene Name:	VPS13B
Uniprot:	Q7Z7G8
Entrez:	157680

Family

Belongs to:

VPS13 family

Alternative Names

cohen syndrome protein 1; DKFZp313I0811; KIAA0532; vacuolar protein sorting 13 homolog B (yeast)

Molecular Weight

Mass (kDA):
448.664 kDA

Genomic Context


Human

Location:	8q22.2
Sequence:	8; NC_000008.11 (99013266..99877586)

Tissue Specificity

Widely expressed. There is apparent differential expression of different transcripts. In fetal brain, lung, liver, and kidney, two transcripts of 2 and 5 kb are identified. These transcripts are also seen in all adult tissues analyzed. A larger transcript (12-14 kb) is expressed in prostate, testis, ovary, and colon in the adult. Expression is very low in adult brain tissue. Isoform 1 and isoform 2 are expressed in brain and retina. Isoform 2 is expressed ubiquitously.

Diseases

Cohen Syndrome
Microcephaly
Myopia
Obesity
Developmental Disabilities
Muscle Hypotonia
Congenital Anomaly Of Face
Retinal Diseases
Dystrophy
Retinitis Pigmentosa
Joint Laxity
Obesity, Abdominal

Retinal Dystrophies
Craniofacial Abnormalities
Developmental Delay (disorder)
Mutation, Out-of-frame
Progressive Myopia
Dwarfism

Pathways

Transport
Intracellular Protein Transport
Neutrophil Differentiation
Golgi Organization
Protein Transport
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VPS13B

References

PMID: 12730828 by Kolehmainen J., et al. Cohen syndrome is caused by mutations in a novel gene, COH1, encoding a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.

PMID: 15498460 by Velayos-Baeza A., et al. Analysis of the human VPS13 gene family.