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- Table of Contents
Proto-oncogene Wnt-1 Antibodies
AND WNT1 ELISA kits, Proto-oncogene Wnt-1 Proteins
Many biological assays use antibodies to detect Proto-oncogene Wnt-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proto-oncogene Wnt-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proto-oncogene Wnt-1 antibodies...
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WNT1 Infographic by Boster Bio
All WNT1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, WB
$380
Cat # M00354
100ul
Cat # M00354
100ul
WNT1 Overview
Facts about Proto-oncogene Wnt-1.
Proto-oncogene Wnt-1 (WNT1)
Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts from the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:23499309, PubMed:26902720, PubMed:28528193, PubMed:23656646).
In certain developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity). Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | WNT1 |
| Uniprot: | P04628 |
| Entrez: | 7471 |
Family
| Belongs to: |
|---|
| Wnt family |
Alternative Names
Int-1; INT1Proto-oncogene Int-1 homolog; proto-oncogene Wnt-1; wingless-type MMTV integration site family, member 1 (oncogene INT1); wingless-type MMTV integration site family, member 1; Wnt1; Wnt-1
Molecular Weight
Mass (kDA):
40.982 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.12 |
| Sequence: | 12; NC_000012.12 (48978322..48982620) |
Subcellular Localizations
Secreted, extracellular space, extracellular matrix. Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Transformation, Neoplastic
- Mammary Neoplasms
- Nervousness
- Crest Syndrome
- Carcinoma
- Malignant Neoplasm Of Breast
- Tissue Adhesions
- Mammary Neoplasms, Experimental
- Carcinogenesis
- Hyperplasia
Pathways
- Cell Proliferation
- Localization
- Cell Death
- Segmentation
- Secretion
- Cell Adhesion
- Neurogenesis
- Regeneration
- Cell Differentiation
- Gastrulation
- Cell Growth
- Cell Cycle
- Pathogenesis
PTMs
- Phosphorylation
- Glycosylation
- Cleavage
- Methylation
- Ubiquitination
- Acetylation
- Demethylation
Research Areas
- Cellular Markers
- Oncogenes
- Stem Cell Signaling Pathway
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WNT1
bosterbio.com/bosterbio-gene-info-cards/WNT1
References
PMID: 2998762 by van Ooyen A., et al. The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences.
PMID: 21244856 by Doubravska L., et al. Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling.
7 Publications of Boster Proto-oncogene Wnt-1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/ol.2014.2647, Suppression of wingless‑type MMTV integration site family, member 1 expression...
- PubMed ID: 10.1002/cbin.10736, KLK4 silencing inhibits the growth of oral squamous cell carcinoma through Wnt/...
- PubMed ID: 33359712, An R,Wang X,Yang L,Zhang J,Wang N,Xu F,Hou Y,Zhang H,Zhang L. Polystyrene microp...
- PubMed ID: 29236323, Effects of microRNA-330 on vulnerable atherosclerotic plaques formation and vasc...
- PubMed ID: 26707142, MicroRNA-148a inhibits breast cancer migration and invasion by directly targetin...
- PubMed ID: 25435937, Dong L, Duan Xc, Han Cx, Zhang H, Wu Y. Oncol Lett. 2015 Jan;9(1):81-85. Epub 20...
- PubMed ID: 25529604, Mi L, Li Y, Zhang Q, Zhao C, Peng Y, Yang G, Zheng X. Biochem Cell Biol. 2015 Fe...
*More publications can be found for each product on its corresponding product page