Caspases are a family of cysteine proteases that respond in succession when activated by apoptosis stimuli, leading to proteolysis, cell disassembly, and apoptosis. The caspase cascade can be triggered by stimuli from the
cell surface or the mitochondria.
The caspase cascade pathway plays a key role in several neurodegenerative disorders, including Parkinson’s disease, Alzheimer’s disease, tumorigenesis, and autoimmune disorders.
Click below to view & download the caspase cascade pathway.