Keywords: Coronavirus, COVID-19, World Health Organization, WHO, Pandemic, Vaccines, Treatment, Research, Journal Cell, SARS-CoV-2, Target Cells, Protein Sspike, Pöhlmann, angiotensin-converting enzyme 2 (ACE2), Enzyme TMPRSS2, Antibodies, SARS-CoV
The World Health Organization has declared COVID-19 as a pandemic. As COVID-19 spreads globally, communities are taking containment and mitigation steps while researchers are working hard to develop effective vaccines and treatments.
A recent research paper published in the journal Cell investigates how SARS-CoV-2, the virus that causes COVID-19, infects target cells through the interaction of its protein spike with the angiotensin-converting enzyme 2 (ACE2) receptor. In the paper, Pöhlmann and his colleagues also discuss that SARS-CoV-2's protein spike is primed by the enzyme TMPRSS2. Furthermore, their research suggests that antibodies against SARS-CoV spike could hinder the ability of SARS-CoV-2 to infect cells.
Keywords: Flow Cytometry, Flow-Validated, Cell Biology, Heterogeneous Fluid Mixture, Multiparametric Analysis, Antibodies, Physical, Chemical, Fluorochromes, Rabbit Monoclonals
Flow cytometry is a popular cell biology technique that utilizes laser-based technology to count, sort, and profile cells in a heterogeneous fluid mixture. It is a powerful tool that allows simultaneous multiparametric analysis of the physical and chemical characteristics of up to thousands of particles per second.
Boster provides a wide range of highly specific antibodies particularly validated for flow cytometry. These primary antibodies include conjugations to some of the most popular fluorochromes in addition to rabbit monoclonals that demonstrate higher affinity and specificity than traditional monoclonals.
Keywords: Western Blot, WB, Western Blotting, Analytical Methods, Science Research, Researchers, Western Blot
First described in 1979, the technique of western blotting has since become one of the most commonly used analytical methods in life science research. Just last week, we received a few questions from confused researchers about weird band sizes in their western blot results
Keywords: Research, Customer, February, Research Spotlight, Bosterbio, Scientists
At Bosterbio, our customers’ research is our priority. Our mission is to help customers achieve their research goals so that they can stay on the cutting edge of research.
This February, we’d like to feature a selected number of recently published research from the scientists whom Boster has served.
Keywords: CD40, Protein, TNFR, Cellular Response, Proliferation, Differentiation, Cell Death, B-cells, Macrophages, Dendritic Cells, Fibroblasts, CD40L, APCs, Gene Expression, Pathways, NF-κB, MAPK, Jak3/STAT3, PI3K, Akt, CD40 Signaling Pathway
CD40, a costimulatory protein member of the TNFR superfamily, has been identified to regulate a broad range of cellular responses, including proliferation, differentiation, and cell death. CD40 can be found on several cell types, such as B cells, macrophages, dendritic cells, and fibroblasts, demonstrating its critical role in immune response and host defense. The binding of CD40L to CD40 stimulates APCs and leads to a number of downstream effects. Different gene expression patterns are activated by CD40 for certain cell types. In addition, several pathways are triggered through CD40 signal transduction. Examples include the NF-κB, MAPK, Jak3/STAT3, and PI3K/Akt pathways.
Keywords: World Cancer Day, February 4th, American Cancer Society, Cancer Mortality, Smoking, Cancer Detection, Cancer Treatment
Today is World Cancer Day. Each year, organizations and people from around the world unite on February 4th to raise awareness about cancer.
According to the American Cancer Society, cancer mortality had dropped 27% from 1991 to 2016. This decline is mostly attributed to decreases in smoking and advancements in early cancer detection and treatment.
Keywords: Picokine ELISA kit, Antigens, ELISA kit, Reproducibility, Cross-reactivity, Sensitivity, Specificity, Stability, Technical Support
With 27 years of experience, Boster provides PicoKine™ ELISA kits powered by proprietary signal-enhancing blocking technology. These ELISA kits can detect antigens in the pg/ml range with low background. We thoroughly validate each lot to ensure lot-to-lot consistency, reproducibility, and cross-reactivity.
Keywords: ELISA, immunoassay, ELISA kit, Good ELISA kit
The ELISA is one of the most popular and powerful immunoassays available. Numerous commercial ELISA kits are offered in the market, but not all ELISA kits are created equal.
How do we sift through the masses and choose a good ELISA kit? Click the orange button to find out what to keep in mind next time you go hunting for an ELISA kit.
Keywords: Product Quality, Scientific, Datasheets, Scientific Expert Team
When you choose Boster, we guarantee product quality and timely support from our scientific experts. Our products are guaranteed to meet specifications on the datasheets. If the product does not work as stated, we will provide a refund or free replacement.
Keywords: Happy New Year, 2020, Share on Facebook, Lab, Word Search
Happy New Year! In 2020, what are your top goals for your lab? Try the word search below to see what you care most about this year.
Share on Facebook and let us know your 3 words in the comments!