Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™

Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™ (96 Tests). Quantitate Rat Tnf in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml. Cited in 236 publication(s).

Product Info Summary

SKU: EK0526
Size: 96 wells/kit, with removable strips.
Reactive Species: Rat
Application: ELISA
Sample Types: cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Product Name

Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™

See all TNF-alpha products

SKU/Catalog Number

EK0526

Size

96 wells/kit, with removable strips.

*Question: How many samples can I assay/run in this kit?

Description

Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™ (96 Tests). Quantitate Rat Tnf in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml.

Storage & Handling

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Cite This Product

Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # EK0526)

Clonality of Antibodies

See Datasheet for details

Immunogen

Expression system for standard: E.coli; Immunogen sequence: L80-L235

Sensitivity

<1 pg/ml

Assay Range

15.6 pg/ml - 1,000 pg/ml (cell culture supernatants), 7.8 pg/ml - 500 pg/ml (serum,plasma)

Cross Reactivity

There is no detectable cross-reactivity with other relevant proteins.

Reactive Species

EK0526 is reactive to Tnf in Rat samples

Validated Sample Types

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).

Application Guarantee

EK0526 is guaranteed for ELISA in Rat by Boster Guarantee

See how Boster Bio validate our ELISA kits: ELISA Validation Information

Kit Components

Catalog Number Description Quantity
EK0526-CAP Anti-Rat Tnf Pre-coated 96-well strip microplate 1
EK0526-ST Rat Tnf Standard 2 vials, 10 ng/tube
EK0526-DA Rat Tnf Biotinylated antibody (100x) 100ul
AR1103 Avidin-Biotin-Peroxidase Complex (100x) 100ul
AR1106-1 Sample Diluent 30ml
AR1106-2 Antibody Diluent 12ml
AR1106-3 Avidin-Biotin-Peroxidase Diluent 12ml
AR1104 Color Developing Reagent (TMB) 10ml
AR1105 Stop Solution 10ml
AR1106-5 Wash Buffer (25x) 20ml
PLA-SEA Adhesive plate sealers 4

*The kit components are not available for individual purchase.

Materials Required But Not Included In Kit

  • Microplate Reader capable of reading absorbance at 450nm.
  • Automated plate washer (optional).
  • Pipettes and pipette tips capable of precisely dispensing 0.5 µl through 1 ml volumes of aqueous solutions.
  • Multichannel pipettes are recommended for large amount of samples.
  • Deionized or distilled water.
  • 500ml graduated cylinders.
  • Test tubes for dilution.

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Validation Standard Curve O.D. At 450nm

Concentration (pg/ml)015.631.262.51252505001000
O.D.0.0100.0310.0620.1320.2030.5550.8841.838

Data Example Images

Recommended Sample Dilution Ratios

According to our internal validation assays using this ELISA kit, to detect TNF-alpha, Dilution ratio of 1:1, concentration in serum is target in serum is below detection limit..

Some articles we found to cite concentrations of TNF-alpha in samples: 24744897 (Pubmed IDs).

Intra Assay Consistency & Inter Assay Consistency

We measured random samples of Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™ within the same batch/lot to ensure the consistency of the kits' performances. ELISA intra assay consistency is measured using wells from the same plate/assay kit. ELISA inter assay consistency is measured using wells from different plates from the same batch production/lot.

Intra-Assay PrecisionInter-Assay Precision
Sample123123
n161616242424
Mean (pg/ml)14962801398306
Standard deviation0.577.3920.440.787.5424.78
CV (%)4.1%7.7%7.3%6%7.7%8.1%

Reproducibility

We ensure reproducibility by testing three samples with differing concentrations of TNF-alpha in ELISA kits from four different production batches/lots.

LotsLot 1 (pg/ml)Lot 2 (pg/ml)Lot 3 (pg/ml)Lot 4 (pg/ml)Mean (pg/ml)Standard DeviationCV (%)
Sample 1141414141400%
Sample 2969392101953.53.6%
Sample 328025827430627917.286.1%
*number of samples for each test n=16.

Gene/Protein Information For Tnf (Source: Uniprot.Org, NCBI)

Uniprot ID

P16599

Gene ID

24835

Gene Name

Tnf

Full Name

Tumor necrosis factor

Weight

25.806kDa

Superfamily

tumor necrosis factor family

Alternative Names

APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha Tnf|RATTNF, TNF-alphaa, Tnf|tumor necrosis factor|tumor necrosis factor|cachectin|tumor necrosis factor (TNF superfamily, member 2)|tumor necrosis factor ligand superfamily member 2

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on Tnf, check out the Tnf Infographic

Tnf infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for Tnf: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

EK0526 has been cited in 236 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Georgieva A,Eftimov M,Todorova M,Kuzmanova V,Kuzmanov A,Kuzmanov K,Vlaskovska M,Valcheva-Kuzmanova S.Effects of ovariectomy-induced estrogen deficit on rat behaviour, lipid metabolism, inflammation, bone mineral density, and turnover.Folia Med (Plovdiv).2021 Jun 30;63(3):385-391.doi:10.3897/folmed.63.e55267.PMID:34196140.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Chen Q,Lei YQ,Liu JF,Wang ZC,Cao H.Beneficial effects of chlorogenic acid treatment on neuroinflammation after deep hypothermic circulatory arrest may be mediated through CYLD/NF-κB signaling.Brain Res.2021 Jun 30:147572.doi:10.1016/j.brainres.2021.147572.Epub ahead of print.PMID:34216581.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

Hou,C.,Wang,X.,Jiang,W.,Bian,Z.,Zhu,L.,& Li,M.(2021).Peptide 11R‑VIVIT promotes fracture healing in osteoporotic rats.International Journal of Molecular Medicine,48,162.https://doi.org/10.3892/ijmm.2021.4995
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BMSCS, DILUTION:NA

Li Q,Jin Y,Ye X,Wang W,Deng G,Zhang X.Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-133a Restrains Myocardial Fibrosis and Epithelial-Mesenchymal Transition in Viral Myocarditis Rats Through Suppressing MAML1.Nanoscale Res Lett.2021 Jul 2;16(1):111.doi:10.1186/s11671-021-03559-2.PMID:34215939.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Tang Q,Shang F,Wang X,Yang Y,Chen G,Chen Y,Zhang J,Xu X.Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: a multi-target therapy for endometriosis rats.J Ethnopharmacol.2014 Feb 12;151(3):1218-1225.doi:10.1016/j.jep.2013.12.047.Epub 2014 Jan 2.PMID: 24389027.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:MACROPHAGES, DILUTION:NA

Wang Y,Chen S,Tan J,Gao Y,Yan H,Liu Y,Yi S,Xiao Z,Wu H.Tryptophan in the diet ameliorates motor deficits in a rotenone-induced rat Parkinson‘s disease model via activating the aromatic hydrocarbon receptor pathway.Brain Behav.2021 Jun 9.doi:10.1002/brb3.2226.Epub ahead of print.PMID:34105899.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Lipopolysaccharides,I.C.I.B.B.,Fesal,M.,Seif,F.,Abdella,A.,& Amin,H.M.Middle East Journal of Applied Sciences Volume:11| Issue: 01|Jan.-March| 2021.
Species: Rat

Ming Tang,Xia Gao,Ting Geng,Xialin Chen,Jiajia Wang,Canjie Shen,Huifang Gao,Mengyu Qian,Zhenzhong Wang,Liang Cao,Wei Xiao,Metabolomics analysis of the therapeutic effects of Qiwei Tongbi oral liquid on rheumatoid arthritis in rats,Journal of Pharmaceutical and Biomedical Analysis, Volume 202,2021,114166,ISSN 0731-7085,https://doi.org/10.1016/j.jpba.2021.114166.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Effect of α-Tocopherol on Cytokines Production, Oxidative Stress, and Liver Injury Induced by Lipopolysaccharides in Male Albino Rats. Amin,H. M.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Cheng Wang,Liang Xian,Shaorui Zheng et al.Cranial Venous Outflow Obstruction Promotes Neuroinflammation And Edema Via ADAM17/solTNF-α/NF-κB Pathway In A Rat Subdural Hematoma Model,11 May 2021,PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-487715/v1]
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

Motavallian A,Bouzari S,Zamani E,Karimian P,Dabirian S,Molavi M,Torshkooh FA.An investigation of the anti-inflammatory effects of gabapentin on acetic acid-induced colitis in rats.Mol Biol Rep.2021 Apr 29.doi:10.1007/s11033-021-06357-2.Epub ahead of print.PMID:33928442.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:COLON TISSUE, DILUTION:NA

Xu H,Wang Y,Luo Y.OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats.Mol Med.2021 Apr 9;27(1):37.doi:10.1186/s10020-021-00297-0.PMID:33836646;PMCID:PMC8035756.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

Ying-nan Ju,Qi-hang Tai,Guang-xiao Xu,Xiao-qing Zhao,Hai-bin Sun,Wei Gao,"Diannexin Can Ameliorate Acute Respiratory Distress Syndrome in Rats by Promoting Heme Oxygenase-1 Expression",Mediators of Inflammation,vol.2021,Article ID 1946384,10 pages,2021.https://doi.org/10.1155/2021/1946384
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BALF AND SERUM, DILUTION:NA

Lixin Xia,Shuo Wang,Zhiwen Jiang,Jinhua Chi,Shuqin Yu,Hongjian Li,Yijie Zhang,Lihua Li,Changren Zhou,Wanshun Liu,Baoqin Han,Hemostatic performance of chitosan-based hydrogel and its study on biodistribution and biodegradability in rats,Carbohydrate Polymers,2021,117965,ISSN 0144-8617,https://doi.org/10. 1016/j.carbpol.2021.117965.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Li Y, Wang N, Ma Z, Wang Y, Yuan Y, Zhong Z, Hong Y, Zhao M. Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways. Int J Mol Med. 2021 May;47(5):86. doi: 10.3892/ijmm. 2021.4919. Epub 2021 Mar 24. PMID: 33760150.
Species: Mouse,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BALF AND RAW264.7 CELL, DILUTION:NA

Abukhalil MH, Althunibat OY, Aladaileh SH, Al-Amarat W, Obeidat HM, Al-Khawalde AAA, Hussein OE, Alfwuaires MA, Algefare AI, Alanazi KM, Al-Swailmi FK, Arab HH, Mahmoud AM. Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats. Biomed Pharmacother. 2021 Mar 19:111410. doi: 10.1016/j.biopha.2021.111410. Epub ahead of print. PMID: 33752930.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:HEART TISSUE, DILUTION:NA

Frosini M, Marcolongo P, Gamberucci A, Tamasi G, Pardini A, Giunti R, Fiorenzani P, Aloisi AM, Rossi C, Pessina F. Effects of Aqueous Extract of Lycopersicum esculentum L. var. “Camone” Tomato on Blood Pressure, Behavior and Brain Susceptibility to Oxidative Stress in Spontaneously Hypertensive Rats. Pathophysiology. 2021; 28(1):189-201. https://doi.org/10. 3390/pathophysiology28010012
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

Zhang P,Gan Z,Tang L,Zhou L,Huang X,Wang J.Exosomes from microRNA-145-5p-modified HUCB-MSCs attenuate CCl4-induced hepatic fibrosis via down-regulating FSCN1 expression.Life Sci.2021 Mar 29:119404.doi:10.1016/j.lfs.2021.119404.Epub ahead of print.PMID:33794251.
Species: Human,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Yin Q,Du T,Yang C,Li X,Zhao Z,Liu R,Yang B,Liu B.Gadd45b is a novel mediator of depression-like behaviors and neuroinflammation after cerebral ischemia.Biochem Biophys Res Commun.2021 Mar 27;554:107-113.doi:10.1016/j.bbrc.2021.03.104.Epub ahead of print.PMID:33784505.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:HIPPOCAMPUS TISSUE, DILUTION:NA

Ouyang, S.,Chen, W.,Gaofeng, Z.,Changcheng, L.,Guoping, T.,Minyan, Z. ... Luo, J. (2021). Cyanidin‑3‑O‑β‑glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF‑β1/p38 MAPK/CREB signaling pathway. Molecular Medicine Reports,23, 338.https://doi.org/10.3892/mmr.2021.11977
Species: Human,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Xiaoling Zhou,Xingwei Xiang,Yufang Zhou,Tianyi Zhou,Shanggui Deng,Bin Zheng,Pingan Zheng,Protective effects of Antarctic krill oil in dextran sulfate sodium-induced ulcerative colitis mice,Journal of Functional Foods,Volume 79,2021,104394,ISSN 1756-4646,h
Species: Mouse
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Martins Ekor,Phyllis E. Owusu Agyei,Ernest Obese,Robert P. Biney,Isaac T. Henneh,Meshack Antwi-Adjei,Ewura S. Yahaya,Gordon Amoakohene,Patrick K. Akakpo bioRxiv 2021.02.15.431245;doi:https://doi.org/10.1101/2021.02.15.431245
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Elmazoglu Z,Galván-Arzate S,Aschner M,Rangel-López E,Bayraktar O,Santamaría A,Karasu Ç.Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ1-42 peptide.Neurochem Int.2021 Feb 19;145:
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:NEURONS, DILUTION:NA

Wang XP,Zheng WC,Bai Y,Li Y,Xin Y,Wang JZ,Chang YL,Zhang LM.Carbon Monoxide-Releasing Molecule-3 Alleviates Kupffer Cell Pyroptosis Induced by Hemorrhagic Shock and Resuscitation via sGC-cGMP Signal Pathway.Inflammation.2021 Feb 11.doi:10.1007/s10753-021-
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

He C,Su C,Zhang W,Zhou Q,Shen X,Yang J,Shi N.Modulatory Potential of LncRNA Zfas1 for Inflammation and Neuronal Apoptosis in Temporal Lobe Epilepsy.Yonsei Med J.2021 Mar;62(3):215-223.doi:10.3349/ymj.2021.62.3.215.PMID:33635011.
Species: Human,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:NEURON, DILUTION:NA

Jia Q,Zhang H,Su Y,Liu X,Bai J,Lang W,Shi Q,Feng M.Strictosamide alleviates the inflammation in an acute ulcerative colitis (UC) model.J Physiol Biochem.2021 Feb 17.doi:10.1007/s13105-021-00796-y.Epub ahead of print.PMID:33595775.
Species: Human,Mouse,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:COLON TISSUE, DILUTION:NA

Hongbei Xu,You Wang,Yong Luo et al. OTULIN is a New Target for EA Treatment in Alleviating Brain Injury and The Activation of Glial Cells By Depressing NF-κB Signalling Pathway in Acute Ischaemic Stroke Rats,28 January 2021,PREPRINT (Version 1) available
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

The maternal western diet exacerbates the inflammatory response in the offspring, but does not alter the action of the non-steroidal antiinflammatory drug. Nathalia Caroline de Oliveira Melo,Nathália Cavalcanti de Morais Araújo,Alexandra Rabello Freire,Maria Bernadete de Souza Maia,Elizabeth do Nascimento
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SKIN TISSUE, DILUTION:NA

Li J,Xie Y,Zhao P,Qin Y,Oliver BG,Tian Y,Li S,Wang M,Liu X. A chinese herbal formula ameliorates COPD by inhibiting the inflammatory response via downregulation of p65, JNK, and p38. Phytomedicine. 2021 Jan 20;83:153475.doi:10.1016/j.phymed.2021.153475.Ep
Species: Human,Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM AND BALF, DILUTION:NA

Haiyang Zhang,Wenjing Jiao,Hailin Cui,Qinghong Sun,Honggang Fan,Combined exposure of alumina nanoparticles and chronic stress exacerbates hippocampal neuronal ferroptosis via activating IFN-γ/ASK1/JNK signaling pathway in rats,Journal of Hazardous Materia
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:HIPPOCAMPUS, DILUTION:NA

Manman Zhao,Junling Gao,Changmeng Cui,Yanan Zhang,Xiaohua Jiang,Jianzhong Cui, "Inhibition of PTEN Ameliorates Secondary Hippocampal Injury and Cognitive Deficits after Intracerebral Hemorrhage: Involvement of AKT/FoxO3a/ATG-Mediated Autophagy",Oxidative
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:HIPPOCAMPUL TISSUE, DILUTION:NA

Jiang,Guoyong and Lei,AItong and Chen,Yi and Yu,Qiang and Xie,Jianhua and Yang,Ying and Yuan,Tongji and Su, Dan", "Protective effects of Ganoderma atrum polysaccharide against acrylamide-induced inflam mation and oxidative damage in rats","Food Funct.","2
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Yingchao Kang, Yaping Sun, Tiantian Li, Zelin Ren,Garcinol protects against cerebral ischemia-reperfusion injury in vivo and in vitro by inhibiting inflammation and oxidative stress, Molecular and Cellular Probes ,2020, 101672,ISSN 0890-8508,https://doi.o
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE AND PC12 CELLS, DILUTION:NA

Wang,Q.,Liu,S.,& Han,Z.(2020).miR-339-3p regulated acute pancreatitis induced by caerulein through targeting TNF receptor-associated factor 3 in AR42J cells, Open Life Sciences , 15(1), 912-922. doi:https://doi.org/10.1515/biol-2020-0084.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:MACROPHAGE, DILUTION:NA

Zhang K,Liu R,Gao Y,Ma W,Shen W.Electroacupuncture Relieves LPS-Induced Depression-Like Behaviour in Rats Through IDO-Mediated Tryptophan-Degrading Pathway.Neuropsychiatr Dis Treat.2020 Oct 5;16:2257-2266.doi:10.2147/NDT.S274778.PMID:33116524;PMCID:PMC754
Species: Rat

Li J,Ma J,Tian Y,Zhao P,Liu X,Dong H,Zheng W,Feng S,Zhang L,Wu M,Zhu L,Liu S,Zhao D.Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signa
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM AND BALF, DILUTION:NA

Süntar I,Cevik CK,Çeribaşı AO,Gökbulut A. Healing effects of Cornus mas L. in experimentally induced ulcerative colitis in rats: From ethnobotany to pharmacology. J Ethnopharmacol.2020 Feb 10;248:112322. doi:10.1016/j.jep.2019.112322. Epub 2019 Oct 20.PMI
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:COLON TISSUE, DILUTION:NA

Liu Y,Zhang X,Yan D,Wang Y,Wang N,Liu Y,Tan A,Chen X,Yan H.Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment.Toxicol Appl Pharmacol.2020 Apr 15;393:114949.doi:10.1016/j.taap.2020.114949.Epu
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Liu L,Zhou J,Wang Y,Qi T,Wang Z,Chen L,Suo N.Imatinib inhibits oxidative stress response in spinal cord injury rats by activating Nrf2/HO-1 signaling pathway.Exp Ther Med.2020 Jan;19(1):597-602.doi:10.3892/etm.2019.8270.Epub 2019 Dec 2.PMID:31897102;PMCID
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SPINAL CORD TISSUE, DILUTION:NA

Feriani A,Tir M,Arafah M,Gómez-Caravaca AM,Contreras MDM,Nahdi S,Taamalli A,Allagui MS,Alwasel S,Segura-Carretero A,Harrath AH,Tlili N. Schinus terebinthifolius fruits intake ameliorates metabolic disorders, inflammation, oxidative stress, and related vas
Species: Rat

Tong L,Tang C,Cai C,Guan X. Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis. Bioengineered. 2020 Nov 17.doi:10.1080/21655979.2020.1851476
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SERUM, DILUTION:NA

Liu S, Wang Y, Lu S, Hu J, Zeng X, Liu W, Wang Y, Wang Z. Sacubitril/valsartan treatment relieved the progression of established pulmonary hypertension in rat model and its mechanism. Life Sci. 2020 Dec 10:118877. doi: 10.1016/j.lfs.2020.118877. Epub ahea
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BLOOD, DILUTION:NA

Zheng X,Cai X,Ye F,Li Y,Wang Q,Zuo Z,Huang W,Wang Z. Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43. BMC Anesthesiol. 2020 Dec 7;20(1):299.doi: 10.1186/s12871-020-01211-7.PMID
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BRAIN TISSUE, DILUTION:NA

Xie M,Cheng M,Wang B,Jiao M,Yu L,Zhu H.2-Bromopalmitate attenuates inflammatory pain by maintaining mitochondrial fission/fusion balance and function. Acta Biochim Biophys Sin (Shanghai).2020 Nov 30:gmaa150. doi: 10.1093/abbs/gmaa150.Epub ahead of print.P
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:SPINAL CORD, DILUTION:NA

Wang Q, Xu GX, Tai QH, Wang Y. Lipoxin A4 Reduces Ventilator-Induced Lung Injury in Rats with Large-Volume Mechanical Ventilation. Mediators Inflamm. 2020 Nov 22;2020:6705985. doi: 10.1155/2020/6705985. PMID: 33299377; PMCID: PMC7704204.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:BALF, DILUTION:NA

Cao Y, Wang L, Lin LT, Wang XR, Ma SM, Yang NN, Fan H, Fisher M, Yang JW. Acupuncture attenuates cognitive deficits through α7nAChR mediated anti-inflammatory pathway in chronic cerebral hypoperfusion rats. Life Sci. 2020 Nov 5:118732. doi: 10.1016/j.lfs.
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:HIPPOCAMPUS, DILUTION:NA

Elmazoglu Z, Prnova MS, Santamaria A, Stefek M, Karasu C. Combatting Nitrosative Stress and Inflammation with Novel Substituted Triazinoindole Inhibitors of Aldose Reductase in PC12 Cells Exposed to 6-Hydroxydopamine Plus High Glucose. Neurotox Res. 2020
Species: Rat
EK0526 usage in article: APP:ELISA, SAMPLE:PC12 CELLS, DILUTION:NA

Zhang, B., Guo, Z., Lai, S., & Chen, H. (2020). Interference with miR-210 Alleviated Renal Injury in Septic Rats by Inhibiting JAK-STAT Pathway. Inflammation, 1-10.

Qin, B., Li, Y., Liu, X., Gong, D., & Zheng, W. (2020). Notch activation enhances microglial CX3CR1/P38 MAPK pathway in rats model of vincristine-induced peripheral neuropathy. Neuroscience Letters, 715, 134624.

Role of heparin on serum VEGF levels and local VEGF contents in reducing the severity of experimental severe acute pancreatitis in rats

W. LIU, L.P. SHAN1, X.S. DONG, X.W. LIU, T. MA, Z. LIU Effect of early fluid resuscitation on the lung in a rat model of lipopolysaccharide-induced septic shock.

Exogenously administered adenosine attenuates renal damage in streptozotocin-induced diabetic rats

Protective effects of oleanolic acid on oxidative stress and the expression of cytokines and collagen by the AKT/NF%u2011%u03BAB pathway in silicotic rats

Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis through the Cascade Pathway of MEKK2%u2013p38 MAPK%u2013IRF-1%u2013TRADD%u2013Caspase 8 in Rat Thy-1 %u2026

Cytotoxic, antitumor and immunomodulatory effects of the water-soluble polysaccharides from lotus (Nelumbo nucifera Gaertn.) seeds

Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa ?-related pathway in rats

Examination of the effect of ovarian radiation injury induced by hysterosalpingography on ovarian proliferating cell nuclear antigen and the radioprotective effect of amifostine: an experimental study

Dendrobium Officinale Kimura et Migo Ameliorates Insulin Resistance in Rats with Diabetic Nephropathy

Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-?B pathway dependent of HDAC3

Efficacy of continuous positive airway pressure treatment in treating obstructive sleep apnea hypopnea syndrome associated with carotid arteriosclerosis

Toxoplasma gondii excretory/secretory antigens (TgESAs) suppress pro-inflammatory cytokine secretion by inhibiting TLR-induced NF-?B activation in LPS-stimulated murine macrophages

Tauroursodeoxycholic acid attenuates endoplasmic reticulum stress and protects the liver from chronic intermittent hypoxia induced injury

Potassium 2-(1-hydroxypentyl)-benzoate attenuates neuronal apoptosis in neuron?astrocyte co-culture system through neurotrophy and neuroinflammation pathway

Repetitive transcranial magnetic stimulation for treatment of lactacystin-induced Parkinsonian rat model

Effect of Helix aspersa extract on TNF?, NF-?B and some tumor suppressor genes in breast cancer cell line Hs578T

Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-?B pathway

Parecoxib reduced ventilation induced lung injury in acute respiratory distress syndrome

Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats

Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats

Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen-Activated Protein Kinase in a Rat Model

Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury

Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-?B Pathway and TNF-?

Sequential Treatments with Tongsai and Bufei Yishen Granules Reduce Inflammation and Improve Pulmonary Function in Acute Exacerbation-Risk Window of Chronic Obstructive Pulmonary Disease in Rats

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats

Protective effect of Astragaloside IV against sepsis-induced acute lung injury in rats

Expression of scavenger receptor A in rat's liver tissue during acute obstructive cholangitis and its significance

Inhibitory Effects of Angelica Polysaccharide on Activation of Mast Cells

Antioxidant and Anti-Inflammatory Effects of Coenzyme Q10 on L-Arginine-Induced Acute Pancreatitis in Rat

Curcumin exerts anti-inflammatory and antioxidative properties in 1-methyl-4-phenylpyridinium ion (MPP(+))-stimulated mesencephalic astrocytes by interference with TLR4 and downstream signaling pathway

Establishment of a novel rat model of severe acute cholangitis

Wound healing treatment by high frequency ultrasound, microcurrent, and combined therapy modifies the immune response in rats

Preconditioning with VEGF Enhances Angiogenic and Neuroprotective Effects of Bone Marrow Mononuclear Cell Transplantation in a Rat Model of Chronic Cerebral Hypoperfusion

The protective role of montelukast against intestinal ischemia-reperfusion injury in rats

The effect of curcumin and its nanoformulation on adjuvant-induced arthritis in rats

In Vivo Evaluation of the Ameliorating Effects of Small-Volume Resuscitation with Four Different Fluids on Endotoxemia-Induced Kidney Injury

Intervening TNF-? via PPAR? with Gegenqinlian Decoction in Experimental Nonalcoholic Fatty Liver Disease

Methionine Sulfoxide Reductase A Negatively Controls Microglia-Mediated Neuroinflammation via Inhibiting ROS/MAPKs/NF-?B Signaling Pathways Through a Catalytic Antioxidant Function

Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway

Epinephrine Enhances the Response of Macrophages under LPS Stimulation

Effect of SP-A/B in lipoic acid on acute paraquat poisoning

Inhibition of TRPM7 Channels Reduces Degranulation and Release of Cytokines in Rat Bone Marrow-Derived Mast Cells

Cerebrolysin Ameloriates Cognitive Deficits in Type III Diabetic Rats

Effect of interferon-? on NF-?B and cytokine IL-18 and IL-27 in acute pancreatitis

Effects of Extract from Mangifera indica Leaf on Monosodium Urate Crystal-Induced Gouty Arthritis in Rats

Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin

Comparison of Anti-Inflammatory and Anti-Nociceptive Activities of Curcuma Wenyujin Y.H. Chen et C. Ling and Scutellaria Baicalensis Georgi

Whether Co-Administration of Garlic has Negative Influence on Scutellaria Baicalensis Georgi in Treating Models Rats with Pelvic Inflammation?

Gao D, Jing S, Zhang Q, Wu G. Exp Ther Med. 2018 Jan;15(1):1029-1035. doi: 10.3892/etm.2017.5479. Epub 2017 Nov 10. Pterostilbene protects against acute renal ischemia reperfusion injury and inhibits oxidative stress, inducible nitric oxide syntha...

Qin S, Gao Z, Liu Y, Liu C, Wang J, Zou LL. Oncol Lett. 2018 Feb;15(2):1630-1638. doi: 10.3892/ol.2017.7477. Epub 2017 Nov 23. Silencing of suppressor of cytokine signaling 1 enhances the immunological effect of mucin 1-calreticulin-primed 4T1 cel...

Chen C, Chen W, Li Y, Dong Y, Teng X, Nong Z, Pan X, Lv L, Gao Y, Wu G. Oncotarget. 2017 Dec 4;8(67):111522-111534. doi: 10.18632/oncotarget.22869. eCollection 2017 Dec 19. Hyperbaric oxygen protects against myocardial reperfusion injury via the i...

He X, Cui LH, Wang XH, Yan ZH, Li C, Gong SD, Zheng Y, Luo Z, Wang Y. Oncotarget. 2017 Dec 8;8(69):113957-113965. doi: 10.18632/oncotarget.23045. eCollection 2017 Dec 26. Modulation of inflammation by toll-like receptor 4/nuclear factor-kappa B in...

Gu X, Zheng C, Zheng Q, Chen S, Li W, Shang Z, Zhang H. Am J Transl Res. 2017 Dec 15;9(12):5643-5652. eCollection 2017. Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage in rats by regulating ERK/P38/Nrf2 signaling.

Liao N, Zheng Y, Xie H, Zhao B, Zeng Y, Liu X, Liu J. Stem Cell Res Ther. 2017 Dec 19;8(1):286. doi: 10.1186/s13287-017-0743-7. Adipose tissue-derived stem cells ameliorate hyperglycemia, insulin resistance and liver fibrosis in the type 2 diabeti...

Sarandy MM, Miranda LL, Alto

Lin X, Ju YN, Gao W, Li DM, Guo CC. Biomed Res Int. 2018 Jan 29;2018:7507314. doi: 10.1155/2018/7507314. eCollection 2018. Desflurane Attenuates Ventilator-Induced Lung Injury in Rats with Acute Respiratory Distress Syndrome

Zhu R, Guo W, Fang H, Cao S, Yan B, Chen S, Zhang K, Zhang S. Mol Med Rep. 2018 May;17(5):6357-6362. doi: 10.3892/mmr.2018.8646. Epub 2018 Feb 27. Kupffer cell depletion by gadolinium chloride aggravates liver injury after brain death in rats

Chen X, Chen C, Fan S, Wu S, Yang F, Fang Z, Fu H, Li Y. J Neuroinflammation. 2018 Apr 20;15(1):116. doi: 10.1186/s12974-018-1151-3. Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulating microglia polarization throu...

Zabihi M, Hajhashemi V, Talebi A, Minaiyan M. EXCLI J. 2017 Mar 30;16:414-425. doi: 10.17179/excli2016-727. eCollection 2017. Evaluation of central and peripheral effects of doxepin on acetic acid-induced colitis in rat and the involved mechanisms

Piao X, Liu B, Guo L, Meng F, Gao L. Oxid Med Cell Longev. 2017;2017:7085709. doi: 10.1155/2017/7085709. Epub 2017 Jun 21. Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy

Li Y, Su R, Xu S, Huang Q, Xu H. Neuropsychiatr Dis Treat. 2017 Sep 27;13:2477-2487. doi: 10.2147/NDT.S145069. eCollection 2017. Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides

Xuanfei L, Hao C, Zhujun Y, Yanming L, Jianping G. Oncotarget. 2017 Mar 28;8(13):21015-21030. doi: 10.18632/oncotarget.15472. Imidazoline I2 receptor inhibitor idazoxan regulates the progression of hepatic fibrosis via Akt-Nrf2-Smad2/3 signaling p...

Zhang L, Xu C, Hu W, Wu P, Qin C, Zhang J. Int J Mol Med. 2018 Mar;41(3):1293-1304. doi: 10.3892/ijmm.2017.3327. Epub 2017 Dec 18. Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway

Qin Q, Xu G, Qi W, Guo M, Wang Z, Xu W, Qiao Z, Gu Y, Niu J. Exp Ther Med. 2017 Aug;14(2):1017-1022. doi: 10.3892/etm.2017.4609. Epub 2017 Jun 15. Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response

Zabihi M, Hajhashemi V, Minaiyan M, Talebi A. Res Pharm Sci. 2017 Aug;12(4):337-345. doi: 10.4103/1735-5362.212052. Evaluation of the central and peripheral effects of doxepin on carrageenan-induced inflammatory paw edema in rat

Yang T, Shi W, Wumaierniyazi Z, Shan L, Miao W, Wu G, Zhou B, Yusup A, Upur H, Aikemu A. Oncotarget. 2017 Oct 6;8(54):92682-92698. doi: 10.18632/oncotarget.21563. eCollection 2017 Nov 3. Enhanced antitumor efficacy and reduced toxicity of Abnormal...

Ling L, Feng X, Wei T, Wang Y, Wang Y, Zhang W, He L, Wang Z, Zeng Q, Xiong Z. Stem Cell Res Ther. 2017 Dec 19;8(1):283. doi: 10.1186/s13287-017-0739-3. Effects of low-intensity pulsed ultrasound (LIPUS)-pretreated human amnion-derived mesenchymal...

Chen Q, Wu H, Tao J, Liu C, Deng Z, Liu Y, Chen G, Liu B, Xu C. PLoS One. 2017 Aug 23;12(8):e0183688. doi: 10.1371/journal.pone.0183688. eCollection 2017. Effect of naringin on gp120-induced injury mediated by P2X7 receptors in rat primary culture...

Yang H, Wu S, Feng R, Huang J, Liu L, Liu F, Chen Y. Stem Cell Res Ther. 2017 Nov 21;8(1):267. doi: 10.1186/s13287-017-0718-8. Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats

Feng XE, Liang TG, Gao J, Kong P, Ge R, Li QS,. Oxid Med Cell Longev. 2017;2017:7028478. doi: 10.1155/2017/7028478. Epub 2017 Jun 14. Heme Oxygenase-1, a Key Enzyme for the Cytoprotective Actions of Halophenols by Upregulating Nrf2 Expression via ...

Zhang S, Li J, Li Y, Liu Y, Guo H, Xu X. Front Physiol. 2017 Apr 27;8:249. doi: 10.3389/fphys.2017.00249. eCollection 2017. Nitric Oxide Synthase Activity Correlates with OGG1 in Ozone-Induced Lung Injury Animal Models

Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, Zhou D, Xiang L. Mol Med Rep. 2017 Jul;16(1):192-200. doi: 10.3892/mmr.2017.6553. Epub 2017 May 9. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats

Chen X, Wu S, Chen C, Xie B, Fang Z, Hu W, Chen J, Fu H, He H. J Neuroinflammation. 2017 Jul 24;14(1):143. doi: 10.1186/s12974-017-0917-3. Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting ...

Xu H, Qin W, Hu X, Mu S, Zhu J, Lu W, Luo Y. J Neuroinflammation. 2018 Mar 15;15(1):83. doi: 10.1186/s12974-018-1117-5. Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activatio...

Yamamoto K, Yamamoto T, Takamura M, Usui S, Murai H, Kaneko S, Taniguchi T. World J Crit Care Med. 2018 Feb 4;7(1):1-8. doi: 10.5492/wjccm.v7.i1.1. eCollection 2018 Feb 4. Effects of mineralocorticoid receptor antagonists on responses to hemorrhag...

Jing HR, Luo FW, Liu XM, Tian XF, Zhou Y. World J Gastroenterol. 2018 Feb 21;24(7):833-843. doi: 10.3748/wjg.v24.i7.833. Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway

Gao, W., Meng, Q.M., Cui, X.G. (2017). Budesonide instillation immediately after reperfusion ameliorates ischemia/reperfusion-induced injury in the transplanted lung of rat. Experimental Lung Research, 43(9-10), 439-446. doi: 10.1080/01902148.2017...

Zhao, B., He, E., Pan, Y., Xu, H., & Song, X. (2017). Kindlin-1 is a key protein in hyperbaric oxygen therapy for the treatment of neuropathic pain. Molecular Pain, 13, 1-10. doi: 10.1177/1744806917730254

Xiong, Q., Ru, Q., Chen, L., Tian, X., & Li, C. (2017). Mitochondrial dysfunction and inflammatory response in the cytotoxicity of NR8383 macrophages induced by fine particulate matter. Environmental Toxicology and Pharmacology, 55, 1-7. Advance o...

Cheng, B., Zheng, H., Wu, F., Wu, J., Liu, X., Tang, C.,..., & Su, Z. (2017). Metabolomics analysis of Danggui Sini decoction on treatment of collagen-induced arthritis in rats. Journal of Chromatography B, 1061-1062, 282-291. doi: 10.1016/j.jchro...

Lu, Y., Lin, B., & Zhong, J. (2017). The therapeutic effect of dexmedetomidine on rat diabetic neuropathy pain and the mechanism. Biological and Pharmaceutical Bulletin. Advance online publication. doi: 10.1248/bpb.b17-00224

Ma Y, Chen F, Yang S, Duan Y, Sun Z, Shi J. Med Sci Monit. 2017 Jun 10;23:2816-2824. Silencing of TRB3 Ameliorates Diabetic Tubule Interstitial Nephropathy via PI3K/AKT Signaling in Rats

Kang, X., Lu, X.G., Zhan, L.B., Liang, Z.K., Guo, W.X., Ma, Q.,…, & Liu, G.H. (2017). Dai-Huang-Fu-Zi-Tang alleviates pulmonary and intestinal injury with severe acute pancreatitis via regulating aquaporins in rats. BMC Complementary and Alternati...

Chen, C.X., Huang, J., Tu, G.Q., Lu, J.T., Xie, X., Zhao, B.,..., & Lu, Y.B. (2017). NAMPT inhibitor protects ischemic neuronal injury in rat brain via anti-neuroinflammation. Neuroscience. Advance online publication. doi: 10.1016/j.neuroscience.2...

Mansour, S.Z., El-Marakby, S.M., & Moawed, F.S.M. (2017). Ameliorative effects of rutin on hepatic encephalopathy-induced by thioacetamide or gamma irradiation. Journal of Photochemistry and Photobiology B: Biology, 172, 20-27. Advance online publ...

Xiao, Q., Yu, W., Tian, Q., Fu, X., Wang, X., Gu, M., & Lü, Y. (2017), Chitinase1 contributed to a potential protection via microglia polarization and Aβ oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments. ...

Toklu HZ, Yang Z, Oktay S, Sakarya Y, Kirichenko N, Matheny MK, Muller-Delp J, Strang K, Scarpace PJ, Wang KKW, Tümer N. Behav Brain Res. 2017 Apr 15. pii: S0166-4328(17)30632-0. doi: 10.1016/j.bbr.2017.04.025. Overpressure blast injury-induced ox...

Ye J, Caihong S, Yayan H, Zhang X, Meitian X. J Sci Food Agric. 2017 Mar 23. doi: 10.1002/jsfa.8322. Anti-fatigue activity of sea cucumber peptides prepared from Stichopus japonicas in an endurance swimming rat model.

Zou X, Huang W, Lu F, Fang K, Wang D, Zhao S, Jia J, Xu L, Wang K, Wang N, Dong H. BMC Complement Altern Med. 2017 Mar 23;17(1):165. doi: 10.1186/s12906-017-1648-9.The effects of Jiao-Tai-Wan on sleep, inflammation and insulin resistance in obesit...

Wang T, Zhou Yt, Chen Xn, Zhu Ax. Braz J Med Biol Res. 2014 Sep;47(9):738-45. Epub 2014 Jul 25. Putative Role Of Ischemic Postconditioning In A Rat Model Of Limb Ischemia And Reperfusion: Involvement Of Hypoxia-Inducible Factor-1?? Expression.

Wei N, Zhang C, He H, Wang T, Liu Z, Liu G, Sun Z, Zhou Z, Bai C, Yuan D. J Pharm Pharmacol. 2014 Nov;66(11):1641-51. Doi: 10.1111/Jphp.12291. Epub 2014 Aug 24. Protective Effect Of Saponins Extract From Panax Japonicus On Myocardial Infarction: I...

Yu Wg, Xu G, Ren Gj, Xu X, Yuan Hq, Qi Xl, Tian Kl. Indian J Med Res. 2011 Nov;134(5):717-24. Doi: 10.4103/0971-5916.91009. Preventive Action Of Curcumin In Experimental Acute Pancreatitis In Mouse.

Shi F, Yang L, Wang J, Kouadir M, Yang Y, Fu Y, Zhou X, Yin X, Zhao D. Acta Biochim Biophys Sin (Shanghai). 2013 Nov;45(11):973-8. Doi: 10.1093/Abbs/Gmt101. Epub 2013 Sep 20. Inhibition Of Phagocytosis Reduced The Classical Activation Of Bv2 Micro...

Zhang S, Liu X, Goldstein S, Li Y, Ge J, He B, Fei X, Wang Z, Ruiz G. Mol Med Rep. 2013 Jan;7(1):93-8. Doi: 10.3892/Mmr.2012.1159. Epub 2012 Oct 29. Role Of The Jak/Stat Signaling Pathway In The Pathogenesis Of Acute Myocardial Infarction In Rats ...

Wang J, Wang Z, Yao Y, Wu J, Tang X, Gu T, Li G. Tuberculosis (Edinb). 2015 Jul;95(4):505-14. Doi: 10.1016/J.Tube.2015.04.006. Epub 2015 May 9. The Fibroblast Growth Factor-2 Arrests Mycobacterium Avium Sp. Paratuberculosis Growth And Immunomodula...

Zhang Hq, Ding Tt, Zhao Js, Yang X, Zhang Hx, Zhang Jj, Cui Yl. World J Gastroenterol. 2009 Apr 21;15(15):1821-8. Therapeutic Effects Of Clostridium Butyricum On Experimental Colitis Induced By Oxazolone In Rats.

Chen J, Chen X, Qin J. Brain Inj. 2011;25(3):292-9. Doi: 10.3109/02699052.2010.546824. Epub 2011 Jan 31. Effects Of Polysaccharides Of The Euphoria Longan (Lour.) Steud On Focal Cerebral Ischemia/Reperfusion Injury And Its Underlying Mechanism.

Wang W, Tang L, Li Y, Wang Y. J Neurol Sci. 2015 Jan 15;348(1-2):121-5. Doi: 10.1016/J.Jns.2014.11.018. Epub 2014 Nov 18. Biochanin A Protects Against Focal Cerebral Ischemia/Reperfusion In Rats Via Inhibition Of P38-Mediated Inflammatory Responses.

Li J, Zhao L, He X, Zeng Yj, Dai Ss. Plos One. 2013;8(3):E59257. Doi: 10.1371/Journal.Pone.0059257. Epub 2013 Mar 15. Sinomenine Protects Against Lipopolysaccharide-Induced Acute Lung Injury In Mice Via Adenosine A(2A) Receptor Signaling.

Alikhani M, Khalighinejad N, Ghalaiani P, Khaleghi Ma, Askari E, Gorsky M. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Jul;118(1):68-71. Doi: 10.1016/J.Oooo.2014.03.007. Epub 2014 Mar 15. Immunologic And Psychologic Parameters Associated With...

Zhang Z, Wu Y, Zhao Y, Xiao X, Liu J, Zhou X. Exp Ther Med. 2013 May;5(5):1523-1527. Epub 2013 Mar 22. Dynamic Changes In Hmgb1 Levels Correlate With Inflammatory Responses During Cardiopulmonary Bypass.

Wang D, Zhu X, Cui C, Dong M, Jiang H, Li Z, Liu Z, Zhu W, Wang Jg. J Chem Inf Model. 2013 Feb 25;53(2):343-53. Doi: 10.1021/Ci3004545. Epub 2013 Jan 30. Discovery Of Novel Acetohydroxyacid Synthase Inhibitors As Active Agents Against Mycobacteriu...

Shen B, Li J, Gao L, Zhang J, Yang B. Mol Cell Biochem. 2013 Jun;378(1-2):137-44. Doi: 10.1007/S11010-013-1604-Z. Epub 2013 Mar 3. Role Of Cc-Chemokine Receptor 5 On Myocardial Ischemia-Reperfusion Injury In Rats.

Yue P, Rong X, Zhuang X, Sha Hj, Li Jm, Xin L, Li Qw. Fish Physiol Biochem. 2014 Apr;40(2):625-34. Doi: 10.1007/S10695-013-9871-X. Epub 2013 Oct 25. Cloning And Expression Analysis Of A Novel High-Mobility Group Box 2 Homologue From Lampetra Japon...

Zhu G, Du Q, Wang X, Tang N, She F, Chen Y. Int J Mol Med. 2014 Jun;33(6):1431-40. Doi: 10.3892/Ijmm.2014.1711. Epub 2014 Mar 24. Tnf-?? Promotes Gallbladder Cancer Cell Growth And Invasion Through Autocrine Mechanisms.

Qin T, Yin Y, Yu Q, Yang Q. Plos One. 2015 Feb 6;10(2):E0117477. Doi: 10.1371/Journal.Pone.0117477. Ecollection 2015. Bursopentin (Bp5) Protects Dendritic Cells From Lipopolysaccharide-Induced Oxidative Stress For Immunosuppression.

Wang Yp, Wu Y, Li Ly, Zheng J, Liu Rg, Zhou Jp, Yuan Sy, Shang Y, Yao Sl. J Neuroinflammation. 2011 Aug 10;8:95. Doi: 10.1186/1742-2094-8-95. Aspirin-Triggered Lipoxin A4 Attenuates Lps-Induced Pro-Inflammatory Responses By Inhibiting Activation O...

Peng J, Wang P, Ge H, Qu X, Jin X. Plos One. 2015 May 1;10(5):E0125902. Doi: 10.1371/Journal.Pone.0125902. Ecollection 2015. Effects Of Cordycepin On The Microglia-Overactivation-Induced Impairments Of Growth And Development Of Hippocampal Culture...

Song Y, Chen X, Wang Ly, Gao W, Zhu Mj. Cns Neurosci Ther. 2013 Aug;19(8):603-10. Doi: 10.1111/Cns.12116. Epub 2013 May 3. Rho Kinase Inhibitor Fasudil Protects Against ??-Amyloid-Induced Hippocampal Neurodegeneration In Rats.

Zhang X, Jin C, Li Y, Guan S, Han F, Zhang S. Food Chem Toxicol. 2013 Aug;58:50-5. Doi: 10.1016/J.Fct.2013.04.006. Epub 2013 Apr 21. Catalpol Improves Cholinergic Function And Reduces Inflammatory Cytokines In The Senescent Mice Induced By D-Galac...

Zhang L, Ya B, Yang P, Sun F, Zhang L, Li Y, Li L. Neurochem Res. 2014 Apr;39(4):653-60. Doi: 10.1007/S11064-014-1242-1. Epub 2014 Jan 29. Impact Of Carotid Atherosclerosis Combined With Hypercholesterolemia On Cerebral Microvessels And Brain Pare...

Song Q, Jiang Z, Li N, Liu P, Liu L, Tang M, Cheng G. Biomaterials. 2014 Aug;35(25):6930-40. Doi: 10.1016/J.Biomaterials.2014.05.002. Epub 2014 May 27. Anti-Inflammatory Effects Of Three-Dimensional Graphene Foams Cultured With Microglial Cells.

Cheleschi S, Cantarini L, Pascarelli Na, Collodel G, Lucherini Om, Galeazzi M, Fioravanti A. Cytokine. 2015 Feb;71(2):165-72. Doi: 10.1016/J.Cyto.2014.10.023. Epub 2014 Nov 17. Possible Chondroprotective Effect Of Canakinumab: An In Vitro Study On...

Ge Gf, Yu Ch, Yu B, Shen Zh, Zhang Dl, Wu Qf. J Ethnopharmacol. 2012 May 7;141(1):178-82. Doi: 10.1016/J.Jep.2012.02.016. Epub 2012 Feb 17. Antitumor Effects And Chemical Compositions Of Eupolyphaga Sinensis Walker Ethanol Extract.

Lin H, Qu Y, Geng Z, Li C, Wu H, Dong N, Liu Z, Li W. Plos One. 2014 Jan 31;9(1):E87368. Doi: 10.1371/Journal.Pone.0087368. Ecollection 2014. Air Exposure Induced Characteristics Of Dry Eye In Conjunctival Tissue Culture.

Hara T, Mimura K, Abe T, Shioi G, Seiki M, Sakamoto T. J Biol Chem. 2011 Sep 16;286(37):32542-51. Doi: 10.1074/Jbc.M111.271726. Epub 2011 Jul 21. Deletion Of The Mint3/Apba3 Gene In Mice Abrogates Macrophage Functions And Increases Resistance To L...

Zhang Y, Leng Yf, Xue X, Zhang Y, Wang T, Kang Yq. World J Gastroenterol. 2011 Jan 14;17(2):254-9. Doi: 10.3748/Wjg.V17.I2.254. Effects Of Penehyclidine Hydrochloride In Small Intestinal Damage Caused By Limb Ischemia-Reperfusion.

Luo H,, Wang X,, Wang J,, Chen C,, Wang N,, Xu Z,, Chen S,, Zeng C,. Cardiovasc Diabetol. 2015 Jun 10;14:76. Doi: 10.1186/S12933-015-0239-7. Chronic Nf-??b Blockade Improves Renal Angiotensin Ii Type 1 Receptor Functions And Reduces Blood Pressure...

Wang T, Zhou Yt, Chen Xn, Zhu Ax, Wu Bh. World J Gastroenterol. 2014 Jul 28;20(28):9519-27. Doi: 10.3748/Wjg.V20.I28.9519. Remote Ischemic Postconditioning Protects Against Gastric Mucosal Lesions In Rats.

Zhang X, Liu F, Liu H, Cheng H, Wang W, Wen Q, Wang Y. Inflamm Res. 2011 Jun;60(6):569-75. Doi: 10.1007/S00011-010-0305-2. Epub 2011 Jan 19. Urinary Trypsin Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury By Blocking The Activati...

Chen T, Liu W, Chao X, Zhang L, Qu Y, Huo J, Fei Z. Brain Res Bull. 2011 Feb 1;84(2):163-8. Doi: 10.1016/J.Brainresbull.2010.11.015. Epub 2010 Dec 4. Salvianolic Acid B Attenuates Brain Damage And Inflammation After Traumatic Brain Injury In Mice.

Li Xj, Liu Dp, Chen Hl, Pan Xh, Kong Qy, Pang Qf. Int Immunopharmacol. 2012 Feb;12(2):460-4. Doi: 10.1016/J.Intimp.2012.01.001. Epub 2012 Jan 15. Lactoferrin Protects Against Lipopolysaccharide-Induced Acute Lung Injury In Mice.

Xia J, Zhou Xl, Zhao Y, Zhu Yq, Jiang S, Ni Sz. Inflammation. 2013 Dec;36(6):1431-9. Doi: 10.1007/S10753-013-9683-2. Roles Of Lipoxin A4 In Preventing Paracetamol-Induced Acute Hepatic Injury In A Rabbit Model.

Tang Y, Liao Y, Kawaguchi-Sakita N, Raut V, Fakhrejahani E, Qian N, Toi M. J Hepatobiliary Pancreat Sci. 2011 Jul;18(4):551-8. Doi: 10.1007/S00534-010-0368-Z. Sinisan, A Traditional Chinese Medicine, Attenuates Experimental Chronic Pancreatitis In...

Chen W, Qi J, Feng F, Wang Md, Bao G, Wang T, Xiang M, Xie Wf. Neurochem Int. 2014 Mar;68:28-37. Doi: 10.1016/J.Neuint.2014.01.015. Epub 2014 Feb 12. Neuroprotective Effect Of Allicin Against Traumatic Brain Injury Via Akt/Endothelial Nitric Oxide...

Ye Xh, Wu Y, Guo Pp, Wang J, Yuan Sy, Shang Y, Yao Sl. Brain Res. 2010 Apr 6;1323:174-83. Doi: 10.1016/J.Brainres.2010.01.079. Epub 2010 Feb 4. Lipoxin A4 Analogue Protects Brain And Reduces Inflammation In A Rat Model Of Focal Cerebral Ischemia R...

Jin Y, Wan Y, Chen G, Chen L, Zhang Mq, Deng L, Zhang Jc, Xiong Xz, Xin Jb. Plos One. 2014 Oct 16;9(10):E111044. Doi: 10.1371/Journal.Pone.0111044. Ecollection 2014. Treg/Il-17 Ratio And Treg Differentiation In Patients With Copd.

Ping C, Yongping Z, Minmin Q, Weiyan Y, Yaozong Y. Dig Dis Sci. 2010 Jun;55(6):1599-609. Doi: 10.1007/S10620-009-0909-Y. Epub 2009 Aug 13. Activated Protein C Improves The Severity Of Severe Acute Pancreatitis Via Up-Regulating The Expressions Of ...

Zhang H, Yin G, Jiang H, Zhang C. J Int Med Res. 2013 Aug;41(4):1179-86. Doi: 10.1177/0300060513488503. Epub 2013 Jun 14. High-Dose N-Acetylcysteine Decreases Silica-Induced Lung Fibrosis In The Rat.

Li Mc, Yang G, Zhou Xd, Tselluyko S, Perelman Jm. Int J Mol Med. 2014 Jan;33(1):83-90. Doi: 10.3892/Ijmm.2013.1535. Epub 2013 Oct 23. The Pathophysiological Mechanisms Underlying Mucus Hypersecretion Induced By Cold Temperatures In Cigarette Smoke...

Ren Dl, Li Yj, Hu Bb, Wang H, Hu B. J Pineal Res. 2015 May;58(4):452-60. Doi: 10.1111/Jpi.12230. Epub 2015 Mar 26. Melatonin Regulates The Rhythmic Migration Of Neutrophils In Live Zebrafish.

Liu L, Li C, Xiang J, Dong W, Cao Z. J Periodontal Res. 2013 Oct;48(5):615-22. Doi: 10.1111/Jre.12047. Epub 2013 Feb 27. Over-Expression And Potential Role Of Cyclophilin A In Human Periodontitis.

Li Y, Li Sy, Li Js, Deng L, Tian Yg, Jiang Sl, Wang Y, Wang Yy. Biol Pharm Bull. 2012;35(10):1752-60. Epub 2012 Aug 3. A Rat Model For Stable Chronic Obstructive Pulmonary Disease Induced By Cigarette Smoke Inhalation And Repetitive Bacterial Infe...

Rizvi W, Fayazuddin M, Shariq S, Singh O, Moin S, Akhtar K, Kumar A. Anc Sci Life. 2014 Jul-Sep;34(1):44-9. Doi: 10.4103/0257-7941.150780. Anti-Inflammatory Activity Of Roots Of Cichorium Intybus Due To Its Inhibitory Effect On Various Cytokines A...

Chen Yf, Zhao Zq, Wu Zm, Zou Zy, Luo Xj, Li J, Xie C, Liang Y. Int J Clin Exp Pathol. 2014 Dec 1;7(12):8411-20. Ecollection 2014. The Role Of Rip1 And Rip3 In The Development Of Aplastic Anemia Induced By Cyclophosphamide And Busulphan In Mice.

Shi L, Song J, Zhang X, Li Y, Li H. Exp Ther Med. 2013 Aug;6(2):532-536. Epub 2013 May 28. Correlation Between The Microinflammatory State And Left Ventricular Structural And Functional Changes In Maintenance Haemodialysis Patients.

Iori E, Vinci B, Murphy E, Marescotti Mc, Avogaro A, Ahluwalia A. Plos One. 2012;7(4):E34704. Doi: 10.1371/Journal.Pone.0034704. Epub 2012 Apr 11. Glucose And Fatty Acid Metabolism In A 3 Tissue In-Vitro Model Challenged With Normo- And Hyperglyca...

Meng H, Shen Y, Shen J, Zhou F, Shen S, Das Un. Lipids Health Dis. 2013 Oct 29;12:160. Doi: 10.1186/1476-511X-12-160. Effect Of N-3 And N-6 Unsaturated Fatty Acids On Prostate Cancer (Pc-3) And Prostate Epithelial (Rwpe-1) Cells In Vitro.

Wang M, Zheng Z, Meng J, Wang H, He M, Zhang F, Liu Y, Hu B, He Z, Hu Q, Wang H. Biomaterials. 2015 Sep;64:78-87. Doi: 10.1016/J.Biomaterials.2015.06.030. Epub 2015 Jun 20. In Vivo Study Of Immunogenicity And Kinetic Characteristics Of A Quantum D...

Chen J, Xu J, Li J, Du L, Chen T, Liu P, Peng S, Wang M, Song H. Int Immunopharmacol. 2015 May;26(1):147-52. Doi: 10.1016/J.Intimp.2015.03.025. Epub 2015 Mar 31. Epigallocatechin-3-Gallate Attenuates Lipopolysaccharide-Induced Mastitis In Rats Via...

Wang Y, Zhang Zz, Wu Y, Zhan J, He Xh, Wang Yl. Exp Ther Med. 2013 Jan;5(1):315-319. Epub 2012 Oct 25. Honokiol Protects Rat Hearts Against Myocardial Ischemia Reperfusion Injury By Reducing Oxidative Stress And Inflammation.

Zhan Y, Wang Z, Yang P, Wang T, Xia L, Zhou M, Wang Y, Wang S, Hua Z, Zhang J. Cell Death Dis. 2014 Jan 9;5:E985. Doi: 10.1038/Cddis.2013.516. Adenosine 5'-Monophosphate Ameliorates D-Galactosamine/Lipopolysaccharide-Induced Liver Injury Through A...

Ma L, Wang G, Chen Z, Li Z, Yao J, Zhao H, Wang S, Ma Z, Chang H, Tian X. Scientificworldjournal. 2014 Mar 16;2014:387640. Doi: 10.1155/2014/387640. Ecollection 2014. Modulating The P66Shc Signaling Pathway With Protocatechuic Acid Protects The In...

Ying Hz, Liu Yh, Yu B, Wang Zy, Zang Jn, Yu Ch. Food Chem Toxicol. 2013 Feb;52:53-60. Doi: 10.1016/J.Fct.2012.10.030. Epub 2012 Nov 2. Dietary Quercetin Ameliorates Nonalcoholic Steatohepatitis Induced By A High-Fat Diet In Gerbils.

Li Q, Zhou X, Kolosov Vp, Perelman Jm. Transl Res. 2010 Dec;156(6):326-34. Doi: 10.1016/J.Trsl.2010.09.001. Epub 2010 Oct 1. Nicotine Suppresses Inflammatory Factors In Hbe16 Airway Epithelial Cells After Exposure To Cigarette Smoke Extract And Li...

Dong Gh, Gong Jp, Li Jz, Luo Yh, Li Zd, Li Pz, He K. Inflammation. 2013 Oct;36(5):1087-93. Doi: 10.1007/S10753-013-9641-Z. Association Between Gene Polymorphisms Of Irak-M And The Susceptibility Of Sepsis.

Li X, Peng F, Xie C, Wu W, Han X, Chen L. Int Immunopharmacol. 2013 Dec;17(4):1125-33. Doi: 10.1016/J.Intimp.2013.10.001. Epub 2013 Oct 14. (E)-3-(3,4-Dimethoxyphenyl)-1-(5-Hydroxy-2,2-Dimethyl-2H-Chromen-6-Yl)Prop-2-En-1-One Ameliorates The Colla...

Guo R, Wu K, Chen J, Mo L, Hua X, Zheng D, Chen P, Chen G, Xu W, Feng J. Cell Physiol Biochem. 2013;32(6):1668-80. Doi: 10.1159/000356602. Epub 2013 Dec 13. Exogenous Hydrogen Sulfide Protects Against Doxorubicin-Induced Inflammation And Cytotoxic...

Wang G, Chen Z, Zhang F, Jing H, Xu W, Ning S, Li Z, Liu K, Yao J, Tian X. Apoptosis. 2014 Sep;19(9):1342-53. Doi: 10.1007/S10495-014-1008-X. Blockade Of Pkc?? Protects Against Remote Organ Injury Induced By Intestinal Ischemia And Reperfusion Via...

Wei Z, Yang Y, Xie C, Li C, Wang G, Ma L, Xiang M, Sun J, Wei Y, Chen L. Fitoterapia. 2014 Sep;97:172-83. Doi: 10.1016/J.Fitote.2014.06.002. Epub 2014 Jun 9. Synthesis And Biological Evaluation Of Pyranoisoflavone Derivatives As Anti-Inflammatory ...

Xu W, Lu Y, Yao J, Li Z, Chen Z, Wang G, Jing H, Zhang X, Li M, Peng J, Tian X. Shock. 2014 Nov;42(5):440-7. Doi: 10.1097/Shk.0000000000000225. Novel Role Of Resveratrol: Suppression Of High-Mobility Group Protein Box 1 Nucleocytoplasmic Transloca...

Sun Ln, Yang Zy, Lv Ss, Liu Xc, Guan Gj, Liu G. Int Immunopharmacol. 2014 Nov;23(1):236-46. Doi: 10.1016/J.Intimp.2014.08.023. Epub 2014 Sep 4. Curcumin Prevents Diabetic Nephropathy Against Inflammatory Response Via Reversing Caveolin-1 Tyr14 Pho...

Zhang F, Li Zl, Xu Xm, Hu Y, Yao Jh, Xu W, Jing Hr, Wang S, Ning Sl, Tian Xf. Mol Med Rep. 2015 Jan;11(1):269-76. Doi: 10.3892/Mmr.2014.2679. Epub 2014 Oct 16. Protective Effects Of Icariin-Mediated Sirt1/Foxo3 Signaling Pathway On Intestinal Isch...

Ni J, Wang X, Chen S, Liu H, Wang Y, Xu X, Cheng J, Jia J, Zhen X. Brain Behav Immun. 2015 Oct;49:75-85. Doi: 10.1016/J.Bbi.2015.04.014. Epub 2015 Apr 29. Microrna Let-7C-5P Protects Against Cerebral Ischemia Injury Via Mechanisms Involving The In...

Jin Y, Zhang Y, Wan C, Wang H, Hou L, Chang J, Fan K, Xie X. Evid Based Complement Alternat Med. 2013;2013:194976. Doi: 10.1155/2013/194976. Epub 2013 Sep 18. Immunomodulatory Activity And Protective Effects Of Polysaccharide From Eupatorium Adeno...

Lu Dh, Guo Xy, Qin Sy, Luo W, Huang Xl, Chen M, Wang Jx, Ma Sj, Yang Xw, Jiang Hx. World J Gastroenterol. 2015 Feb 7;21(5):1531-45. Doi: 10.3748/Wjg.V21.I5.1531. Interleukin-22 Ameliorates Liver Fibrogenesis By Attenuating Hepatic Stellate Cell Ac...

Xie Wl, Shi Q, Zhang J, Zhang By, Gong Hs, Guo Y, Wang Sb, Xu Y, Wang K, Chen C, Liu Y, Dong Xp. J Mol Neurosci. 2013 Nov;51(3):919-32. Doi: 10.1007/S12031-013-0002-Z. Epub 2013 Mar 24. Abnormal Activation Of Microglia Accompanied With Disrupted C...

Cai C, Chen Y, Zhong S, Ji B, Wang J, Bai X, Shi G. Plos One. 2014 Apr 21;9(4):E95931. Doi: 10.1371/Journal.Pone.0095931. Ecollection 2014. Anti-Inflammatory Activity Of N-Butanol Extract From Ipomoea Stolonifera In Vivo And In Vitro.

Fan Z, Jing H, Yao J, Li Y, Hu X, Shao H, Shen G, Pan J, Luo F, Tian X. Oxid Med Cell Longev. 2014;2014:191624. Doi: 10.1155/2014/191624. Epub 2014 Aug 20. The Protective Effects Of Curcumin On Experimental Acute Liver Lesion Induced By Intestinal...

Zheng Ls, Kaneko N, Sawamoto K. Front Cell Neurosci. 2015 Jan 28;9:5. Doi: 10.3389/Fncel.2015.00005. Ecollection 2015. Minocycline Treatment Ameliorates Interferon-Alpha- Induced Neurogenic Defects And Depression-Like Behaviors In Mice.

Xu R, Tao A, Zhang S, Zhang M. Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(9):726-33. Doi: 10.1093/Abbs/Gmt065. Epub 2013 Jun 19. Neutralization Of Interleukin-17 Attenuates High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease In Mice.

Liu W, Dong Xs, Sun Yq, Liu Z. Int J Clin Exp Med. 2014 Apr 15;7(4):919-26. Ecollection 2014. A Novel Fluid Resuscitation Protocol: Provide More Protection On Acute Kidney Injury During Septic Shock In Rats.

Zhang Gb, Tian Lq, Li Ym, Liao Yf, Li J, Bing Fh. Phytomedicine. 2013 Aug 15;20(11):964-8. Doi: 10.1016/J.Phymed.2013.04.009. Epub 2013 Jun 6. Protective Effect Of Homonojirimycin From Commelina Communis (Dayflower) On Influenza Virus Infection In...

Yin Y, Qin T, Yu Q, Yang Q. Amino Acids. 2014 Jul;46(7):1763-74. Doi: 10.1007/S00726-014-1735-X. Epub 2014 Apr 8. Bursopentin (Bp5) From Chicken Bursa Of Fabricius Attenuates The Immune Function Of Dendritic Cells.

Tang D, Gao J, Wang S, Yuan Z, Ye N, Chong Y, Xu C, Jiang X, Li B, Yin W, Miao Y, Wang D, Jiang K. Tumour Biol. 2015 Jul;36(7):5617-26. Doi: 10.1007/S13277-015-3233-5. Epub 2015 Mar 1. Apoptosis And Anergy Of T Cell Induced By Pancreatic Stellate ...

Chen X, Zhao C, Li X, Wang T, Li Y, Cao C, Ding Y, Dong M, Finci L, Wang Jh, Li X, Liu L. Nat Chem Biol. 2015 Jan;11(1):19-25. Doi: 10.1038/Nchembio.1657. Epub 2014 Nov 10. Terazosin Activates Pgk1 And Hsp90 To Promote Stress Resistance.

Liu R, An L, Liu G, Li X, Tang W, Chen X. Antiviral Res. 2015 Aug;120:101-11. Doi: 10.1016/J.Antiviral.2015.05.008. Epub 2015 May 27. Mouse Lung Slices: An Ex Vivo Model For The Evaluation Of Antiviral And Anti-Inflammatory Agents Against Influenz...

Dai M, Wu L, He Z, Zhang S, Chen C, Xu X, Wang P, Gruzdev A, Zeldin Dc, Wang Dw. J Cell Physiol. 2015 Sep;230(9):2108-19. Doi: 10.1002/Jcp.24939. Epoxyeicosatrienoic Acids Regulate Macrophage Polarization And Prevent Lps-Induced Cardiac Dysfunction.

Li Q, Zhou X, Kolosov Vp, Perelman Jm. Cell Biochem Biophys. 2012 Apr;62(3):421-31. Doi: 10.1007/S12013-011-9324-Z. The Expression And Pharmacological Characterization Of Nicotinic Acetylcholine Receptor Subunits In Hbe16 Airway Epithelial Cells.

Yu J, Lu Y, Li Y, Xiao L, Xing Y, Li Y, Wu L. J Pharm Pharmacol. 2015 Sep;67(9):1240-50. Doi: 10.1111/Jphp.12415. Epub 2015 Apr 16. Role Of S100A1 In Hypoxia-Induced Inflammatory Response In Cardiomyocytes Via Tlr4/Ros/Nf-??b Pathway.

Huang L, Cao J. Oxid Med Cell Longev. 2014;2014:248786. Doi: 10.1155/2014/248786. Epub 2014 Mar 5. The Protective Effects Of Shen-Fu Injection On Experimental Acute Pancreatitis In A Rat Model.

Qiu Jl, Zhu Wl, Lu Yj, Bai Zf, Liu Zg, Zhao P, Sun C, Zhang Yb, Li H, Liu W. Neurochem Int. 2015 Jun-Jul;85-86:46-52. Doi: 10.1016/J.Neuint.2015.04.007. Epub 2015 May 4. The Selective Mglur5 Agonist Chpg Attenuates So2-Induced Oxidative Stress And...

Ozkan Zs, Deveci D, Kumbak B, Simsek M, Ilhan F, Sekercioglu S, Sapmaz E. J Reprod Immunol. 2014 Jun;103:53-8. Doi: 10.1016/J.Jri.2013.11.002. Epub 2013 Dec 8. What Is The Impact Of Th1/Th2 Ratio, Socs3, Il17, And Il35 Levels In Unexplained Infert...

Presti I, D'Orazio G, Labra M, La Ferla B, Mezzasalma V, Bizzaro G, Giardina S, Michelotti A, Tursi F, Vassallo M, Di Gennaro P. Appl Microbiol Biotechnol. 2015 Jul;99(13):5613-26. Doi: 10.1007/S00253-015-6482-8. Epub 2015 Mar 7. Evaluation Of The...

Wu Z, Ming Y, Zhang Z, Wu J, Wu Z, Yao S. Chin Med J (Engl). 2014;127(5):968-70. Edaravone Rescues The Lung By Inhibiting Lipid Peroxidation And Pro-Inflammatory Cytokines In A Rat Model.

Liang Y, Liu Hh, Chen Yj, Sun H. J Med Food. 2014 Apr;17(4):439-46. Doi: 10.1089/Jmf.2013.2846. Epub 2014 Mar 4. Antitumor Activity Of The Protein And Small Molecule Component Fractions From Agrocybe Aegerita Through Enhancement Of Cytokine Produc...

Yu Zm, Liu Zh, Chen J, Zeng Q. Chin J Integr Med. 2014 Dec;20(12):934-43. Doi: 10.1007/S11655-014-1863-X. Epub 2014 Nov 27. Anti-Inflammatory Effect Of Qingwen Baidu Decoction (????????????

Eker Ss, Yavasci Eo, Cangur S, Kirli S, Sarandol E. Acta Neuropsychiatr. 2014 Oct;26(5):291-7. Doi: 10.1017/Neu.2014.13. Can Bdnf And Il-2 Be Indicators For The Diagnosis In Schizophrenic Patients With Depressive Symptoms?

Wang G, Ji Y, Li Z, Han X, Guo N, Song Q, Quan L, Wang T, Han W, Pang D, Ouyang H, Tang X. Sci Rep. 2014 May 9;4:4905. Doi: 10.1038/Srep04905. Nitro-Oleic Acid Downregulates Lipoprotein-Associated Phospholipase A2 Expression Via The P42/P44 Mapk A...

Li J, Huang M, Shen X. J Diabetes Complications. 2014 Sep-Oct;28(5):662-6. Doi: 10.1016/J.Jdiacomp.2014.06.008. Epub 2014 Jun 19. The Association Of Oxidative Stress And Pro-Inflammatory Cytokines In Diabetic Patients With Hyperglycemic Crisis.

Liu H, Yang Lx, Guo Rw, Zhu Gf, Shi Yk, Wang Xm, Qi F, Guo Cm, Ye Js, Yang Zh, Liang X. Int J Cardiol. 2013 Oct 9;168(4):3248-53. Doi: 10.1016/J.Ijcard.2013.04.141. Epub 2013 May 1. Functional Blockage Of Emmprin Ameliorates Atherosclerosis In Apo...

Lin Y, Liu Hl, Fang J, Yu Ch, Xiong Yk, Yuan K. Food Chem Toxicol. 2014 Jun;68:290-6. Doi: 10.1016/J.Fct.2014.03.026. Epub 2014 Mar 29. Anti-Fatigue And Vasoprotective Effects Of Quercetin-3-O-Gentiobiose On Oxidative Stress And Vascular Endotheli...

Zhang W, Chen Dq, Qi F, Wang J, Xiao Wy, Zhu Wz. J Cardiovasc Pharmacol. 2010 Jan;55(1):96-105. Doi: 10.1097/Fjc.0B013E3181C9548B. Inhibition Of Calcium-Calmodulin-Dependent Kinase Ii Suppresses Cardiac Fibroblast Proliferation And Extracellular M...

Qin Jh, Ma Jz, Yang Xw, Hu Yj, Zhou J, Fu Lc, Tian Rh, Liu S, Xu G, Shen Xl. Nat Prod Bioprospect. 2015 Jun;5(3):159-66. Doi: 10.1007/S13659-015-0063-5. Epub 2015 Jun 16. A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation And Allev...

Liu W, Shan Lp, Dong Xs, Liu Xw, Ma T, Liu Z. World J Gastroenterol. 2013 Jan 28;19(4):492-502. Doi: 10.3748/Wjg.V19.I4.492. Combined Early Fluid Resuscitation And Hydrogen Inhalation Attenuates Lung And Intestine Injury.

Tang D, Kang R, Xiao W, Zhang H, Lotze Mt, Wang H, Xiao X. Am J Respir Cell Mol Biol. 2009 Dec;41(6):651-60. Doi: 10.1165/Rcmb.2008-0119Oc. Epub 2009 Mar 5. Quercetin Prevents Lps-Induced High-Mobility Group Box 1 Release And Proinflammatory Funct...

Zhang Wg, He L, Shi Xm, Wu Ss, Zhang B, Mei L, Xu Yj, Zhang Zx, Zhao Jp, Zhang Hl. Respir Res. 2014 Mar 25;15:33. Doi: 10.1186/1465-9921-15-33. Regulation Of Transplanted Mesenchymal Stem Cells By The Lung Progenitor Niche In Rats With Chronic Obs...

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11 Customer Q&As for Rat TNF Alpha/Tumor necrosis factor ELISA Kit PicoKine™

Question

Does EK0526 contain any recombinant proteins expressed in baculoviral system? Which kit components are recombinant proteins and what species?

Verified customer

Asked: 2021-11-25

Answer

The standard in the Rat TNF Alpha ELISA Kit PicoKine™ (EK0526) is a recombinant rat protein expressed in E.coli system.

Boster Scientific Support

Answered: 2021-12-01

Question

Q: What is the optimal O.D. value for TNF-alpha ELISA kit? I performed your TNF-alpha ELISA on serum samples. For my positive control, I received an O.D. value of 0.826, while my negative control received a value of 0.136. I obtained both of these controls from the ELISA kit, where your kit's typical data shows O.D. values much higher than my positive control and your background is lower. My samples O.D. values are around 0.225 and the highest is only 0.357. is it safe to say these samples contain TNF-alpha even though the O.D. values are not very high?

L. Anand

Verified customer

Asked: 2020-12-21

Answer

A: The absolute O.D. values may change according to incubation time. The more you incubate the higher the O.D. values are going to be. what you should focus on is whether your sample O.D. values are statistically significantly higher than your blank values. in the above example, you could extend your development time in the substrate incubation step to obtain higher O.D. values, as long as your negative controls' O.D. values are not increasing faster in relation to your positive controls. typically, a sample with O.D. value 2 standard deviations higher than your negative controls can be considered positive. We calculate the sensitivity of this ELISA kit by converting cutoff O.D. value, calculated as the average of 20 negative controls plus 2 standard deviations of the 20 negative controls, into a concentration. in other words, when we claim this TNF-alpha ELISA kit to have sensitivity of 1pg/ml, that means the minimum amount of TNF-alpha that can be declared/interpreted as positive by the above standard is 1pg/ml.

Boster Scientific Support

Answered: 2020-12-21

Question

Q: Can TNF-alpha ELISA Kits be used with tissue homogenates (or other non-validated sample types)?

Verified Customer

Verified customer

Asked: 2020-01-11

Answer

A: Unfortunately, Boster Bio has not routinely validated tissue homogenates as a sample type for ELISA kits. This does not mean that ELISA kits are not suitable for other sample types than we have tested: it means further investigation is required. One will need to perform a spike and recovery study to determine if an unvalidated sample type will work with a particular kit. To perform a spike and recovery experiment, one should divide a sample into two aliquots. In one of the aliquots, the user should spike in a known amount of the kit standard. a dilution series is performed comparing the spiked versus the unspiked sample. Generally, samples with expected recovery and linearity between 80-120% are considered acceptable. This method can be used to validate any sample type that has not been assessd by Boster Bio. for a more detailed spike and recovery protocol, please contact technical support.
Note: acceptable ranges should be determined individually by each laboratory. Additionally, technical support can help determine if a buffer component is not compatible with a given ELISA kit. please view the Citations tab on the product webpage for peer-reviewed papers utilizing a wide range of sample types. We also have an innovator's reward program where if the user validates our ELISA kits in applications or samples previously not validated by Boster Bio or other users, and share such information with us by submit a review, we will reward the user's efforts with a free antibody or ELISA kit from our catalog. Biocompare.com will also give $20 Amazon giftcard as an additional reward, if the review is submitted there as well.

Boster Scientific Support

Answered: 2020-01-11

Question

Q: is it okay to use citrate plasma as samples in Rat TNF-alpha Picokine® ELISA Kit (Catalog # EK0526)?

Verified Customer

Verified customer

Asked: 2019-11-23

Answer

A: Chelating agents such as EDTA, Heparin and Citrate can sequester metal ions from the functional domain of TNF-alpha causing degradation of its protein structure. TNF-alpha may be denatured as a result and may compromise the assay's measurements. The chilating sites could also be too close to the epitopes a must for detection and block the antigen antibody reaction. We have tested the TNF-alpha ELISA, treating samples with different anticoagulants and decided that heparin or EDTA can be used for treatment of blood/plasma samples. Do not use other anticoagulents when collecting samples.

Boster Scientific Support

Answered: 2019-11-23

Question

Is EK0526 able to detect the non-soluble form of TNF alpha?

Verified Customer

Verified customer

Asked: 2019-10-11

Answer

EK0526 is able to detect the non-soluble form of TNF alpha.

Boster Scientific Support

Answered: 2019-10-11

Question

Q: Are Boster Bio recombinant proteins and antibodies sterile?

G. Moore

Verified customer

Asked: 2019-08-23

Answer

A: although the vials are bottled using aseptic techniques, heat-treated vials, and sterile stock solutions, they are not considered or guaranteed to be sterile. If sterile material is required for an experiment, the material can be filtered through a 0.2 micron filter designed for use with biological fluids.

Boster Scientific Support

Answered: 2019-08-23

Question

To Boster Support: I have a question about EK0526 Rat TNF Alpha ELISA Kit, what is the minimum detectable concentration of TNF alpha? I want to be able to detect as little as 5 pg/ml.

Verified Customer

Verified customer

Asked: 2019-08-22

Answer

The limit of detection of EK0526 Rat TNF Alpha ELISA Kit is 15 pg/ml, which is reached at by taking the mean optical density of 64 blank wells (no TNF alpha), then add two standard deviations of the mean, then calculating the corresponding concentration from the standard curve, including one or more standard dilutions will not improve the sensitivity.

Boster Scientific Support

Answered: 2019-08-22

Question

Q: for how much duration can samples (cell cultures, serum, and plasma) be stored and still be stable for quantification TNF-alpha using the EK0526 Rat TNF-alpha Picokine® ELISA Kit?

Verified Customer

Verified customer

Asked: 2019-01-27

Answer

A: Boster Bio does not assess sample stability. Variations in sample collection, processing, and storage may change the stabilityof samples. It is recommend to assay sample on-stat collection when possible, or aliquot into single use volumes and store samples frozen. avoid repeat freeze-thaw cycles with the stored samples to prevent protein degradation.

Boster Scientific Support

Answered: 2019-01-27

Question

Q: how to thaw whole blood sample for TNF-alpha ELISA after freezing?

R. Wang

Verified customer

Asked: 2018-10-10

Answer

A: do not freeze and thaw whole blood. erythrocytes are fragile and, if frozen and thawed, will undergo hemolysis rendering the samples useless. To keep your blood samples to test TNF-alpha for a later time, you should let the blood clot in glass tubes and collect the serum to freeze for later use.

Boster Scientific Support

Answered: 2018-10-10

Question

Q: we need your suggestion regarding the dilution ratio of serum samples for detection of TNF-alpha in Rat cell lysates? I am trying to measure a few analytes and it requires 100ul of diluted samples for each well. We have low serum quantitys so we like to dilute as much as possible.

C. Collins

Verified customer

Asked: 2018-09-16

Answer

A: unable to understand the physiological or pathological context of your samples we cannot recommend a dilution ratio without performing a pilot test with your samples. Here is how you can perform a pilot study on your own: perform a serial dilution of your samples on the TNF-alpha ELISA kit to make sure you have a linear ascending curve followed by a plateau, which signifies the samples saturating the detection limit of the kit. Then you can pick the dilution ratios from samples in the linear part of the curve as your experimental dilution ratio.
If you are interested in using our ELISA service, you can also send us your sample and we will take care of everything for you. You can check our service details here: bosterbio.com/services/assay-services/ELISA-testing-service
Since you mentioned you have limited samples, our cost effective multiplex ELISA service would fit perfectly for your needs, where we can generate dozens of data points using as little as 25ul sample volume. Information on this service is also in the above link.

Boster Scientific Support

Answered: 2018-09-16

Question

I want to measure Rat TNF Alpha using your product EK0526 Rat TNF Alpha ELISA Kit in rat hippocampus tissues. I read the manual and it stated that the EK0526 Rat TNF Alpha ELISA Kit can measure these cytokines level but it is not specified in what kind of buffer it must be homogenize the tissues. My concern is that; Can I use using homgenates in Lysis buffer 150 mM sodium chloride, 1.0% Triton X-100, 50 mM Tris pH 8.0)?

Verified Customer

Verified customer

Asked: 2016-10-13

Answer

That lysis buffer is good, the 150 mM sodium chloride, 1.0% Triton X-100, 50 mM Tris pH 8.0. Please check these general rules: Do not use >0.1% SDS or other strongly denaturing detergents. Non-ionic detergents such as Triton X-100 or NP-40 are best, although zwitterionic detergents such as CHAPS, or mild ionic detergents such as sodium deoxycholate will also work. Use no more than 2% v/v total detergent. Do not use sodium azide and avoid using >10 mM reducing agents, such as dithiothreitol or mercaptoethanols. Hence, e strongly recommend to add a protease inhibitor cocktail to the lysis buffer prior to homogenization.

Boster Scientific Support

Answered: 2016-10-13

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