Anti-ARG2 Antibody Picoband®

Anti-ARG2 Antibody Picoband®
View all ARG2 Antibodies

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Rabbit IgG

No cross-reactivity with other proteins.

39 kDa

ARG2 (arginase, type II) encodes a 355-amino acid polypeptide.Using Northern blotting and RT-PCR,Vockley et al. (1996)found thatARG2is expressed as a 1.5-kb mRNA in a wide variety of tissues, with highest levels of expression in prostate, brain, and kidney.By PCR analysis of somatic cell hybrid panels, fluorescence in situ hybridization, and radiation hybrid analysis,theARG2 gene is mapped to 14q24.1-q24.3. ARG2may be inducible and may be essential in the regulation of nitric oxide synthesis by modulating local arginine concentrations. Gotoh et al. (1996)showed thatARG2mRNA and nitric oxide synthase (NOS) mRNA were coinduced by lipopolysaccharide in a macrophage-like cell line. Arginase II has been implicated in the regulation of the arginine/ornithine concentrations in the cell. The mitochondrial location ofARG2and its coinduction with ornithine aminotransferase and involvement with proline biosynthesis in lactating rat mammary gland had led to the inference thatARG2is involved in biosynthetic functions, as opposed to the metabolic ones of the urea cycle.