This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Arginase-2, mitochondrial Antibodies
AND ARG2 ELISA kits, Arginase-2, mitochondrial Proteins
Many biological assays use antibodies to detect Arginase-2, mitochondrial, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Arginase-2, mitochondrial in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Arginase-2, mitochondrial antibodies...
Previous: A1BG
Next: RHOA
ARG2 Infographic by Boster Bio
All ARG2 Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # PA1805
100 μg/vial
Cat # PA1805
100 μg/vial
Anti-ARG2 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02244
100 μg/vial
Cat # A02244
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02244-1
100 μg/vial
Cat # A02244-1
100 μg/vial
Dog, Human, Rat
IF, IHC, WB
$523
Cat # M02244
100 µl
Cat # M02244
100 µl
Anti-Arg2 Rabbit Monoclonal Antibody
1 Citations
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M02244-1
100 μl/vial
Cat # M02244-1
100 μl/vial
ARG2 Overview
Facts about Arginase-2, mitochondrial.
Arginase-2, mitochondrial (ARG2)
Extrahepatic arginase functions to modulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is an essential regulator of innate and adaptive immune responses.
Appears to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells (PubMed:27745970). May contribute to the immune evasion of H.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARG2 |
| Uniprot: | P78540 |
| Entrez: | 384 |
Family
| Belongs to: |
|---|
| arginase family |
Alternative Names
ARG2; Arginase 2; arginase, type II; Arginase-2; arginase-2, mitochondrial; EC 3.5.3; EC 3.5.3.1; kidney arginase; Kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; nonhepatic arginase; Non-hepatic arginase; Type II Arginase
Molecular Weight
Mass (kDA):
38.578 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.1 |
| Sequence: | 14; NC_000014.9 (67619920..67651708) |
Tissue Specificity
Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas. Expressed in activated T cells (PubMed:27745970).
Subcellular Localizations
Mitochondrion.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Asthma
- Carcinoma
- Cell Transformation, Neoplastic
- Disease Of Adrenal Medulla
- Inflammatory Response
- Hyperargininemia
- Hypertensive Disease
- Thyroid Neoplasm
- Diabetes Mellitus
- Spondylarthropathies
Pathways
- Transport
- Immune Response
- Urea Cycle
- Inflammatory Response
- Methylation
- Pathogenesis
- Translation
- Cell Proliferation
- Proteolysis
- Wound Healing
- Localization
- Mating
- Oncogenesis
PTMs
- Methylation
- Phosphorylation
- Deamination
- Acetylation
- Oxidation
- Cleavage
- Sumoylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARG2
bosterbio.com/bosterbio-gene-info-cards/ARG2
References
PMID: 8898077 by Gotoh T., et al. Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line.
PMID: 8954792 by Vockley J.G., et al. Cloning and characterization of the human type II arginase gene.
1 Publications of Boster Arginase-2, mitochondrial Antibodies & ELISA Kits
- PubMed ID: 10.1007/s13770-021-00405-5, The Therapeutic Effects of Exosomes Derived from Human Umbilical Cord Mesenchyma...
*More publications can be found for each product on its corresponding product page