Anti-eIF2 Alpha (2E4) monoclonal EIF2S1 Antibody

eIF2 alpha/EIF2S1 antibody

Boster Bio Anti-eIF2 Alpha (2E4) monoclonal EIF2S1 Antibody catalog # M04387-1. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: M04387-1
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: IF, WB

Product Name

Anti-eIF2 Alpha (2E4) monoclonal EIF2S1 Antibody

View all eIF2 alpha/EIF2S1 Antibodies

SKU/Catalog Number

M04387-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-eIF2 Alpha (2E4) monoclonal EIF2S1 Antibody catalog # M04387-1. Tested in WB,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-eIF2 Alpha (2E4) monoclonal EIF2S1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04387-1)

Host

Mouse

Contents

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Monoclonal

Clone Number

7D11

Isotype

IgG

Immunogen

Purified recombinant fragment of Calcyclin expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M04387-1 is reactive to EIF2S1 in Human, Mouse, Rat

Applications

M04387-1 is guaranteed for IF, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

36.112kDa

Background of eIF2 alpha/EIF2S1

Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol–anchored glycoprotein present on the cell surface of various human solid tumors. The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol–anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell. Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues, such as mesothelium, but aberrantly over expressed in mesotheliomas, ovarian, and pancreatic cancers. The biological functions of mesothelin remain elusive. A recent study showed that mesothelin binds to MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000
IF: 1:50-200

Validation Images & Assay Conditions

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Gene/Protein Information For EIF2S1 (Source: Uniprot.org, NCBI)

Gene Name

EIF2S1

Full Name

Eukaryotic translation initiation factor 2 subunit 1

Weight

36.112kDa

Superfamily

eIF-2-alpha family

Alternative Names

eIF2 alpha; EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha; EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; EIF2S1 EIF2S1 EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A eukaryotic translation initiation factor 2 subunit alpha eukaryotic translation initiation factor 2 subunit 1|eIF-2-alpha|eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on EIF2S1, check out the EIF2S1 Infographic

EIF2S1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for EIF2S1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M04387-1-100ul

100ul

$482

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