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- Table of Contents
ENDOG antibody (M05147) performs well in ELISA, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Western blot analysis of EndoG expression in HepG2 cell lysate with EndoG antibody at (A) 2.5 and (B) 5 μg/mL.
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Anti-EndoG Monoclonal Antibody [7G1C10]
ENDOG antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Mouse | ELISA, WB |
Recommend Dilution
Application
Dilution
Species
EndoG monoclonal antibody can be used for detection of EndoG by Western blot at 2.5 - 5 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-EndoG Monoclonal Antibody [7G1C10]
View all ENDOG Antibodies
View all ENDOG Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
EndoG monoclonal antibody can be stored at 4°C, stable for one year.
Host
Mouse
Contents
EndoG Monoclonal Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Monoclonal
Clone Number
Clone: 7G1C10
Isotype
IgG1
Immunogen
Recombinant protein corresponding to amino acids 51 - 140 of human EndoG.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
32.6 kDa
Background of ENDOG
The fragmentation of nuclear DNA is a hallmark of apoptotic cell death. The activities of caspase and nuclease are involved in the DNA fragmentation. Caspase-activated deoxyribonuclease (CAD), also termed DNA fragmentation factor (DFF40), is one such nuclease, and is capable of inducing DNA fragmentation and chromatin condensation after cleavage by caspase-3 of its inhibitor ICAD/DFF45. Caspase and CAD independent DNA fragmentation also exists. Recent studies demonstrated that another nuclease, endonuclease G (EndoG), is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD. EndoG is a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. The homologue of mammalian EndoG is the first mitochondrial protein identified to be involved in apoptosis in C. elegans. EndoG also cleaves DNA in vitro.
Cite This Product
Anti-EndoG Monoclonal Antibody [7G1C10] (Boster Biological Technology, Pleasanton CA, USA, Catalog # M05147)
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Product Promise
We promise Anti-EndoG Monoclonal Antibody [7G1C10] performs excellently in relevant applications for ELISA, WB. If it doesn't perform as promised, we will refund the product. Learn more
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M05147
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 9, 2026