Click image to see more details
Product Info Summary
| SKU: | M02632-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC-F, ICC, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-VE-Cadherin CDH5-Monoclonal Antibody
SKU/Catalog Number
M02632-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-VE-Cadherin CDH5-Monoclonal Antibody (Catalog# M02632-1). Tested in Flow Cytometry, IP, WB, IHC-F, ICC application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-VE-Cadherin CDH5-Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02632-1)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
55-7H1
Isotype
Mouse IgG1 kappa
Immunogen
Human endothelial cells. The mouse monoclonal antibody 55-7H1 recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M02632-1 is reactive to CDH5 in Human
Observed Molecular Weight
42 kDa
Calculated molecular weight
87.5 kDa
Background of CDH5
CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02632-1 is guaranteed for Flow Cytometry, IP, IHC-F, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
Click image to see more details
Separation of HUVEC cells stained using anti-CD144 (55-7H1) purified antibody (concentration in sample 5 µg/ml, GAM APC, red-filled) from HUVEC cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
Specific Publications For Anti-VE-Cadherin CDH5-Monoclonal Antibody (M02632-1)
Loading publications
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-VE-Cadherin CDH5-Monoclonal Antibody?
Share your experimental results or join a short interview to earn up to $1,000 in product credits or other rewards.
0 Reviews For Anti-VE-Cadherin CDH5-Monoclonal Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
