Anti-LEKTI (H525) SPINK5 Antibody

SPINK5 antibody

Boster Bio Anti-LEKTI (H525) SPINK5 Antibody catalog # A03254-1. Tested in WB,IHC applications. This antibody reacts with Human.

Product Info Summary

SKU: A03254-1
Size: 100ul
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-LEKTI (H525) SPINK5 Antibody

View all SPINK5 Antibodies

SKU/Catalog Number

A03254-1

Size

100ul

Form

Liquid

Description

Boster Bio Anti-LEKTI (H525) SPINK5 Antibody catalog # A03254-1. Tested in WB,IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-LEKTI (H525) SPINK5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03254-1)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human RAC3 protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03254-1 is reactive to SPINK5 in Human

Applications

A03254-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

120.714kDa

Background of SPINK5

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Kwak K.S., Cancer Res. 64:8193-8198(2004).
Dgany O., Am. J. Hum. Genet. 71:1467-1474(2002).
Ota T., Nat. Genet. 36:40-45(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For SPINK5 (Source: Uniprot.org, NCBI)

Gene Name

SPINK5

Full Name

Serine protease inhibitor Kazal-type 5

Weight

120.714kDa

Alternative Names

Kazal type 5; LEKTI; LETKI; NETS; serine peptidase inhibitor, Kazal type 5; SPINK5; VAKTI SPINK5 LEKTI, LETKI, NETS, NS, VAKTI serine peptidase inhibitor Kazal type 5 serine protease inhibitor Kazal-type 5|lympho-epithelial Kazal-type-related inhibitor|lymphoepithelial Kazal-type-related inhibitor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on SPINK5, check out the SPINK5 Infographic

SPINK5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SPINK5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A03254-1-100ul

100ul

$405

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