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- Table of Contents
P2RX7 antibody (A01208) performs well in ELISA, IF, ICC, WB and shows reactivity with Human, Mouse.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
- Over 1 Publication
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Immunofluorescence of P2RX7 in 3T3 cells with P2RX7 antibody at 20 μg/mL.
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Anti-P2X purinoceptor 7 P2RX7 Antibody
P2RX7 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse | Rabbit | ELISA, IF, ICC, WB |
Recommend Dilution
Application
Dilution
Species
P2RX7 antibody can be used for detection of P2RX7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-P2X purinoceptor 7 P2RX7 Antibody
View all P2RX7 Antibodies
View all P2RX7 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
P2RX7 antibody can be stored at 4°C, stable for up to one year.
Host
Rabbit
Contents
P2RX7 antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
P2RX7 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7. The immunogen is located within the last 50 amino acids of P2RX7.
Cross-Reactivity
P2RX7 antibody is human, mouse, and rat reactive. Multiple isoforms of P2RX7 are known to exist.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
68.6 kDa
Background of P2RX7
The purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) belongs to the family of purinoceptors for ATP (1). This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules (1,2). Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression (2). Recent studies have suggested that P2RX7 may play a key role in immune-mediated diseases such as rheumatoid arthritis (3) as well as neuropsychiatric disorders (4).
Cite This Product
Anti-P2X purinoceptor 7 P2RX7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01208)
Publications
Application:
Species:
Zou Z,Wang Q,Zhou M,Li W,Zheng Y,Li F,Zheng S,He Z.Protective effects of P2X7R antagonist in sepsis-induced acute lung injury in mice via regulation of circ_0001679 and circ_0001212 and downstream Pln, Cdh2, and Nprl3 expression.J Gene Med.2020 Dec;22(12)
Species: Mouse
PMID: 32783373
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Product Promise
We promise Anti-P2X purinoceptor 7 P2RX7 Antibody performs excellently in relevant applications for ELISA, IF, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
A01208
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 9, 2026