ABCC5 Antibodies

AND ABCC5 ELISA kits, ABCC5 Proteins

Many biological assays use antibodies to detect ABCC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCC5 antibodies...

We validate the specificity of these antibodies to ABCC5 by testing them on tissues known to express ABCC5 positively and negatively. Browse below to find the ABCC5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for ABCC5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ABCC5 IHC Guide

ABCC5 Infographic by Boster Bio

All ABCC5 Products

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Product

Figures

Specificity

Applications

Price

Anti-MRP5/ABCC5 Antibody

Flow Cytometry analysis of PC-3 cells using anti-MRP5/ABCC5 antibody (A03040-1)

Human

ELISA, Flow Cytometry, IHC

$370
Cat # A03040-1
100 μg/vial

MRP5 (ABCC5) (NM_001023587) Human Over-expression Lysate

Human

$628
Cat # LS010057
20 µg, 100 µg

ABCC5 Overview

Facts about Multidrug resistance-associated protein 5.

ABCC5 3D structure. Source: alphafold

Multidrug resistance-associated protein 5 (ABCC5)

Acts as a multispecific organic anion pump that may transport nucleotide analogs. .

Gene Information

Human
Gene Name:	ABCC5
Uniprot:	O15440
Entrez:	10057

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ATP-binding cassette sub-family C member 5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5; canalicular multispecific organic anion transporter C; EST277145; MOAT-CABC33; MRP5MOATC; multidrug resistance-associated protein 5; Multi-specific organic anion transporter C; pABC11; SMRPDKFZp686C1782

Molecular Weight

Mass (kDA):
160.66 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (183919934..184018010, complement)

Tissue Specificity

All isoforms are equally expressed in retina.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Breast
Hiv Infections
Mammary Neoplasms
Liver Carcinoma
Leukemia
Malignant Neoplasm Of Lung
Malignant Paraganglionic Neoplasm
Pancreatic Neoplasm
Lung Neoplasms
Malignant Neoplasm Of Pancreas

Epilepsy
Liver Neoplasms
Immunologic Deficiency Syndromes
Adenocarcinoma
Leukemia, Myelocytic, Acute
Colorectal Cancer
Myeloid Leukemia

Pathways

Transport
Drug Resistance
Localization
Cell Proliferation
Cgmp Transport
Pathogenesis
Reverse Transcription
Drug Transport
Immune Response
Cell Differentiation
Transmembrane Transport
Cyclic Nucleotide Transport
Nucleotide Transport

Cell Growth
Rna Interference
Excretion
Cell Adhesion
Gene Silencing
Stem Cell Differentiation
Aging

PTMs

Phosphorylation
Biotinylation

Carboxylation
Amidation

Methylation

Research Areas

ABC Transporters
Amino Acids, Drugs and other small molecules
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCC5

References

PMID: 9827529 by Belinsky M.G., et al. Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

PMID: 10438534 by McAleer M.A., et al. pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells.