Anti-MRP5/ABCC5 Antibody Picoband™

ABCC5 antibody

Boster Bio Anti-MRP5/ABCC5 Antibody Picoband™ catalog # A03040-1. Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.

Product Info Summary

SKU: A03040-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, Flow Cytometry, IHC

Product Name

Anti-MRP5/ABCC5 Antibody Picoband™

View all ABCC5 Antibodies

SKU/Catalog Number

A03040-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MRP5/ABCC5 Antibody Picoband™ catalog # A03040-1. Tested in ELISA, Flow Cytometry, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MRP5/ABCC5 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03040-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human MRP5/ABCC5 recombinant protein (Position: K647-D1409).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03040-1 is reactive to ABCC5 in Human

Applications

A03040-1 is guaranteed for ELISA, Flow Cytometry, IHC Boster Guarantee

Background of ABCC5

Multidrug resistance-associated protein 5 is a protein that in humans is encoded by the ABCC5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9- (2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For ABCC5 (Source: Uniprot.org, NCBI)

Uniprot ID

O15440

Gene ID

10057

Gene Name

ABCC5

Full Name

Multidrug resistance-associated protein 5

Weight

160.66kDa

Superfamily

ABC transporter superfamily

Alternative Names

ATP-binding cassette sub-family C member 5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5; canalicular multispecific organic anion transporter C; EST277145; MOAT-CABC33; MRP5MOATC; multidrug resistance-associated protein 5; Multi-specific organic anion transporter C; pABC11; SMRPDKFZp686C1782 ABCC5 ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 ATP binding cassette subfamily C member 5 multidrug resistance-associated protein 5|ATP-binding cassette, sub-family C (CFTR/MRP), member 5|canalicular multispecific organic anion transporter C|multi-specific organic anion transporter C

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ABCC5, check out the ABCC5 Infographic

ABCC5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ABCC5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]

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Conjugation

Total: $315

SKU:A03040-1

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A03040-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$315.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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