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- Table of Contents
ABCE1 Antibodies
AND ABCE1 ELISA kits, ABCE1 Proteins
Many biological assays use antibodies to detect ABCE1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCE1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCE1 antibodies...
Designing a Western blot for ABCE1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ABCE1 Western Blot GuideABCE1 Infographic by Boster Bio
All ABCE1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A04173
100 μg/vial
Cat # A04173
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # PB10020
100 μg/vial
Cat # PB10020
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M04173
100 μl/vial
Cat # M04173
100 μl/vial
ABCE1 Overview
Facts about ATP-binding cassette sub-family E member 1.
ATP-binding cassette sub-family E member 1 (ABCE1)
Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and so inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover.
Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
Gene Information
| Human | |
|---|---|
| Gene Name: | ABCE1 |
| Uniprot: | P61221 |
| Entrez: | 6059 |
Family
| Belongs to: |
|---|
| ABC transporter superfamily |
Alternative Names
2'-5'-oligoadenylate-binding protein; ATP-binding cassette, sub-family E (OABP), member 1; huHP68; OABP; Ribonuclease 4 inhibitor; ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor; RLIABC38; RNase L inhibitor; RNASEL1; RNASELIRNS4IATP-binding cassette sub-family E member 1
Molecular Weight
Mass (kDA):
67.314 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q31.21 |
| Sequence: | 4; NC_000004.12 (145098311..145129524) |
Subcellular Localizations
Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
Diseases
- Malignant Neoplasms
- Hiv Infections
- Neoplasms
- Virus Diseases
- Carcinoma
- Immunologic Deficiency Syndromes
- Lung Neoplasms
- Neoplasm Metastasis
- Adenocarcinoma
- Chronic Fatigue Syndrome
- Liver Carcinoma
- Prostatic Neoplasms
Pathways
- Translation
- Cell Growth
- Transport
- Pathogenesis
- Localization
- Rna Interference
- Muscle Cell Differentiation
- Gene Silencing
- Virulence
- Tropism
- Cell Division
- Cell Differentiation
- Myoblast Differentiation
PTMs
- Phosphorylation
Research Areas
- ABC Transporters
- Immune System Diseases
- Immunology
- Lipid and Metabolism
- Membrane Trafficking and Chaperones
- Plasma Membrane Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCE1
bosterbio.com/bosterbio-gene-info-cards/ABCE1
References
PMID: 7539425 by Bisbal C., et al. Cloning and characterization of a RNase L inhibitor. A new component of the interferon-regulated 2-5A pathway.
PMID: 8641422 by Aubry F., et al. Chromosomal localization and expression pattern of the RNase L inhibitor gene.