Roundabout homolog 2 Antibodies

AND ROBO2 ELISA kits, Roundabout homolog 2 Proteins

Many biological assays use antibodies to detect Roundabout homolog 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Roundabout homolog 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Roundabout homolog 2 antibodies...

We validate the specificity of these antibodies to Roundabout homolog 2 by testing them on tissues known to express ROBO2 positively and negatively. Browse below to find the ROBO2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ROBO2 Infographic by Boster Bio

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Anti-Roundabout homolog 2 Robo2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A02085
100ul

ROBO2 Overview

Facts about Roundabout homolog 2.

ROBO2 3D structure. Source: alphafold

Roundabout homolog 2 (ROBO2)

Receptor for SLIT2, and probably SLIT1, which are considered to act as molecular guidance cue in cell regeneration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. .

Gene Information

Human
Gene Name:	ROBO2
Uniprot:	Q9HCK4
Entrez:	6092

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

Drosophila) homolog 2; ROBO2; roundabout, axon guidance receptor, homolog 2 (Drosophila); SAX3

Molecular Weight

Mass (kDA):
151.2 kDA

Genomic Context


Human

Location:	3p12.3
Sequence:	3; NC_000003.12 (75906675..77649964)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Nervousness
Malignant Neoplasms
Gastroesophageal Reflux Disease
Neoplasms
Vesico-ureteral Reflux
Muscular Fasciculation
Tissue Adhesions
Colorectal Cancer
Congenital Abnormality
Kidney Failure
Developmental Disabilities
Kidney Diseases
Carcinoma

Cell Transformation, Neoplastic
Kidney Failure, Chronic
Peripheral Nerve Injuries
Tumor Angiogenesis
Mycoplasma Pneumonia
Cell Invasion
Nerve Damage

Pathways

Axon Guidance
Cell Migration
Regeneration
Pathogenesis
System Development
Kidney Development
Cell Adhesion
Neurogenesis
Cell Proliferation
Endothelial Cell Migration
Innervation
Reverse Transcription
Ureteric Bud Development

Methylation
Nervous System Development
Heart Morphogenesis
Angiogenesis
Forebrain Development
Rna Interference
Secretion

PTMs

Methylation
Demethylation

Phosphorylation
Biotinylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ROBO2

References

PMID: 16829019 by Yue Y., et al. Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice.

PMID: 9458045 by Kidd T., et al. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.