Long-chain-fatty-acid--CoA ligase 5 (ACSL5)

Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity).

Utilizes a wide assortment of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It had been suggested that it may also stimulate fatty acid oxidation (By similarity).