This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
ACSL5 Antibodies
AND ACSL5 ELISA kits, ACSL5 Proteins
Many biological assays use antibodies to detect ACSL5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACSL5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACSL5 antibodies...
Designing a Western blot for ACSL5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACSL5 Western Blot GuideACSL5 Infographic by Boster Bio
All ACSL5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, ICC, WB
$370
Cat # A05087-3
100 μg/vial
Cat # A05087-3
100 μg/vial
ACSL5 Overview
Facts about Long-chain-fatty-acid--CoA ligase 5.
Long-chain-fatty-acid--CoA ligase 5 (ACSL5)
Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity).
Utilizes a wide assortment of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It had been suggested that it may also stimulate fatty acid oxidation (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | ACSL5 |
| Uniprot: | Q9ULC5 |
| Entrez: | 51703 |
Family
| Belongs to: |
|---|
| ATP-dependent AMP-binding enzyme family |
Alternative Names
ACS2; ACS5FACL5 for fatty acid coenzyme A ligase 5; acyl-CoA synthetase long-chain family member 5; EC 6.2.1; EC 6.2.1.3; FACL5fatty acid coenzyme A ligase 5; fatty-acid-Coenzyme A ligase, long-chain 5; LACS 5; Long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; long-chain-fatty-acid--CoA ligase 5
Molecular Weight
Mass (kDA):
75.991 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q25.2 |
| Sequence: | 10; NC_000010.11 (112374116..112428380) |
Subcellular Localizations
Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Glioma
- Malignant Paraganglionic Neoplasm
- Adenoma
- Malignant Neoplasm Of Brain
- Celiac Disease
- Adenocarcinoma
- Steatosis
- Colorectal Neoplasms
- Carcinogenesis
- Colorectal Cancer
- Malignant Glioma
Pathways
- Transport
- Fatty Acid Transport
- Cell Death
- Cell Proliferation
- Gene Silencing
- Fatty Acid Oxidation
- Pathogenesis
- Mrna Splicing
- Immune Response
PTMs
- Oxidation
Research Areas
- Cancer
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACSL5
bosterbio.com/bosterbio-gene-info-cards/ACSL5
References
PMID: 17681178 by Gassler N., et al. Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing.
PMID: 19459852 by Mashima T., et al. Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.