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- Table of Contents
Facts about Long-chain-fatty-acid--CoA ligase 5.
Utilizes a wide assortment of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It had been suggested that it may also stimulate fatty acid oxidation (By similarity).
| Human | |
|---|---|
| Gene Name: | ACSL5 |
| Uniprot: | Q9ULC5 |
| Entrez: | 51703 |

| Belongs to: |
|---|
| ATP-dependent AMP-binding enzyme family |

ACS2; ACS5FACL5 for fatty acid coenzyme A ligase 5; acyl-CoA synthetase long-chain family member 5; EC 6.2.1; EC 6.2.1.3; FACL5fatty acid coenzyme A ligase 5; fatty-acid-Coenzyme A ligase, long-chain 5; LACS 5; Long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; long-chain-fatty-acid--CoA ligase 5
Mass (kDA):
75.991 kDA

| Human | |
|---|---|
| Location: | 10q25.2 |
| Sequence: | 10; NC_000010.11 (112374116..112428380) |
Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane.





PMID: 17681178 by Gassler N., et al. Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing.
PMID: 19459852 by Mashima T., et al. Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.