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- Table of Contents
Afamin Antibodies
AND AFM ELISA kits, Afamin Proteins
Many biological assays use antibodies to detect Afamin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Afamin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Afamin antibodies...
Designing a Western blot for Afamin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AFM Western Blot GuideAFM Infographic by Boster Bio
All AFM Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00275-3
100 μg/vial
Cat # A00275-3
100 μg/vial
AFM Overview
Facts about Afamin.
Afamin (AFM)
Functions as carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed:26902720).
Binds vitamin E (PubMed:15952736, PubMed:12463752). May transfer vitamin E in your body fluids under conditions where the lipoprotein system isn't sufficient (PubMed:15952736).
Gene Information
| Human | |
|---|---|
| Gene Name: | AFM |
| Uniprot: | P43652 |
| Entrez: | 173 |
Family
| Belongs to: |
|---|
| ALB/AFP/VDB family |
Alternative Names
Afamin; AFM; ALB2; ALB2alpha-Alb; ALBA; ALBAalpha-albumin; ALF; Alpha-Alb; Alpha-albumin; MGC125338; MGC125339
Molecular Weight
Mass (kDA):
69.069 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (73481745..73504001) |
Tissue Specificity
High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level).
Subcellular Localizations
Secreted.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Edema
- Submersion
- Neoplasms
- Headache
- Dehydration
- Patient Dependence On
- Alzheimer's Disease
- Fracture
- Carcinoma
- Pancreatic Acinar Atrophy
Pathways
- Transport
- Cell Adhesion
- Localization
- Cell Growth
- Conjugation
- Regeneration
- Aging
- Cell Proliferation
- Pathogenesis
- Metaphase
- Cell Death
- Secretion
- Biofilm Formation
PTMs
- Oxidation
- Cleavage
- Biotinylation
- Carboxylation
- Reduction
- Phosphorylation
- Nitration
- Methylation
- Acetylation
- Amination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AFM
bosterbio.com/bosterbio-gene-info-cards/AFM
References
PMID: 7517938 by Lichenstein H.S., et al. Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family.
PMID: 8755513 by Nishio H., et al. Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family.
1 Publications of Boster Afamin Antibodies & ELISA Kits
- PubMed ID: 22509346, Iori E, Vinci B, Murphy E, Marescotti Mc, Avogaro A, Ahluwalia A. Plos One. 2012...
*More publications can be found for each product on its corresponding product page