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- Table of Contents
AKR1D1 Antibodies
AND AKR1D1 ELISA kits, AKR1D1 Proteins
Many biological assays use antibodies to detect AKR1D1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR1D1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR1D1 antibodies...
Designing a Western blot for AKR1D1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AKR1D1 Western Blot GuideAKR1D1 Infographic by Boster Bio
All AKR1D1 Products
Product
Figures
Specificity
Applications
Price
Anti-AKR1D1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05278-2
100 μg/vial
Cat # A05278-2
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A05279-3
100 μg/vial
Cat # A05279-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M05324
100 μg/vial
Cat # M05324
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M05278
100 μg/vial
Cat # M05278
100 μg/vial
AKR1D1 Overview
Facts about Aldo-keto reductase family 1 member D1.
Aldo-keto reductase family 1 member D1 (AKR1D1)
Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7- alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4- cholesten-3-one can also act as substrates.
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Gene Information
| Human | |
|---|---|
| Gene Name: | AKR1D1 |
| Uniprot: | P51857 |
| Entrez: | 6718 |
Family
| Belongs to: |
|---|
| aldo/keto reductase family |
Alternative Names
3o5bred; Aldo-keto reductase family 1 member D1,3-oxo-5-beta-steroid 4-dehydrogenase; aldo-keto reductase family 1, member D1 (delta4-3-ketosteroid-5-beta-reductase); CBAS2; Delta(4)-3-oxosteroid 5-beta-reductase; EC 1.3.1.3; SRD5B1beta polypeptide 1 (3-oxo-5 beta-steroid delta4-dehydrogenase beta 1)
Molecular Weight
Mass (kDA):
37.377 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q33 |
| Sequence: | 7; NC_000007.14 (138076459..138118305) |
Tissue Specificity
Highly expressed in liver. Expressed in testis and weakly in colon.
Subcellular Localizations
Cytoplasm.
Diseases
- Liver Failure
- Endometriosis, Site Unspecified
- Malignant Neoplasms
- Malignant Neoplasm Of Prostate
- Cholestasis
- Cholangiocarcinoma
- Premature Obstetric Labor
- Liver Diseases
- Neonatal Hepatitis
- Inborn Errors Of Metabolism
- Malignant Neoplasm Of Breast
- Endometrial Polyp
Pathways
- Parturition
- Protein Folding
- Pathogenesis
- Excretion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR1D1
bosterbio.com/bosterbio-gene-info-cards/AKR1D1
References
PMID: 7508385 by Kondo K.-H., et al. Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta- reductase and substrate specificity of the expressed enzyme.
PMID: 11342103 by Charbonneau A., et al. Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme.