Aldehyde dehydrogenase family 1 member A3 (ALDH1A3)

NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097). Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097).

Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal areas; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity). .