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- Table of Contents
ALDH1A3 Antibodies
AND ALDH1A3 ELISA kits, ALDH1A3 Proteins
Many biological assays use antibodies to detect ALDH1A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALDH1A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALDH1A3 antibodies...
Designing a Western blot for ALDH1A3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ALDH1A3 Western Blot GuideDesigning an IHC experiment for ALDH1A3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ALDH1A3 IHC GuideALDH1A3 Infographic by Boster Bio
All ALDH1A3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03030
100 μg/vial
Cat # A03030
100 μg/vial
ALDH1A3 Overview
Facts about Aldehyde dehydrogenase family 1 member A3.
Aldehyde dehydrogenase family 1 member A3 (ALDH1A3)
NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097). Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097).
Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal areas; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | ALDH1A3 |
| Uniprot: | P47895 |
| Entrez: | 220 |
Family
| Belongs to: |
|---|
| aldehyde dehydrogenase family |
Alternative Names
aldehyde dehydrogenase 1 family, member A3; Aldehyde dehydrogenase 6; aldehyde dehydrogenase family 1 member A3; ALDH1A6; ALDH6acetaldehyde dehydrogenase 6; EC 1.2.1; EC 1.2.1.5; RALDH3; RALDH-3; Retinaldehyde dehydrogenase 3
Molecular Weight
Mass (kDA):
56.108 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q26.3 |
| Sequence: | 15; NC_000015.10 (100879831..100916626) |
Tissue Specificity
Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Carcinogenesis
- Cell Transformation, Neoplastic
- Corneal Diseases
- Lung Diseases
- Liver Carcinoma
- Malignant Paraganglionic Neoplasm
- Hernia
- Hypoplasia
Pathways
- Cell Cycle
- Cell Death
- Cell Cycle Arrest
- Eye Development
- Cell Proliferation
- Dna Repair
- Localization
- Methylation
- Hair Cycle
- Pathogenesis
- Transport
- Cell Adhesion
- Catagen
PTMs
- Methylation
Research Areas
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALDH1A3
bosterbio.com/bosterbio-gene-info-cards/ALDH1A3
References
PMID: 7698756 by Hsu L.C., et al. Molecular cloning, genomic organization, and chromosomal localization of an additional human aldehyde dehydrogenase gene, ALDH6.
PMID: 23591992 by Yahyavi M., et al. ALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm.