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- Table of Contents
Facts about Fructose-bisphosphate aldolase A.
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Human | |
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Gene Name: | ALDOA |
Uniprot: | P04075 |
Entrez: | 226 |
Belongs to: |
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class I fructose-bisphosphate aldolase family |
ALDA; aldolase A, fructose-bisphosphate; EC 4.1.2.13; fructose-1,6-bisphosphate triosephosphate-lyase; fructose-bisphosphate aldolase A; GSD12; Lung cancer antigen NY-LU-1; MGC10942; MGC17716; MGC17767; Muscle-type aldolase
Mass (kDA):
39.42 kDA
Human | |
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Location: | 16p11.2 |
Sequence: | 16; NC_000016.10 (30064279..30070420) |
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+).
If you're interested in learning how to use the ALDOA marker, you've come to the right place. Here, you'll find tips and tricks for making the most of this useful biomarker. TIA, aCI, TFK-1, HuCCT1, rhodopsin, and rhodopsin are just a few of the applications available.
The ALDOA marker is a powerful molecular marker used for many applications. Its dried format enables it to be used in a variety of methods, such as western blotting. It is particularly convenient because it does not require titration, amplification, or refrigeration prior to use. Additionally, dried cocktails have a shelf life of at least 12 months, and are easy to handle.
Using an antibody against the ALDOA molecule, a biochemical marker for the Aldolase protein, can be a valuable tool for the detection of gene expression in various tissues. Antibodies for the ALDOA protein have been developed and tested for use in ICC, IF, and IHC applications. The Boster Bio ALDOA antibody is highly specific to human Aldolase, and can be used to detect this marker in a wide range of biological samples.
The ALDOA marker is a widely used marker for cancer research. This marker can be used in a wide range of applications, including drug discovery and development. For this reason, researchers are increasingly relying on this marker to analyze cancer cells. In this study, we used ALDOA to determine whether the ALDOA protein binds to the ALDOA receptor in HuCCT1 cells.
The expression of miR-137 in HuCCT1 cells inhibits their colony formation ability. Furthermore, the induced expression of miR-137 correlated with decreased tumor growth in vivo. Western blotting analysis indicated that the overexpression of miR-137 reduced the growth of HuCCT1 cells, reducing their weight. Similarly, the overexpression of the ALDOA marker in HuCCT1 cells inhibited tumor formation in vitro and in vivo.
PMID: 3840020 by Sakakibara M., et al. Nucleotide sequence of a cDNA clone for human aldolase: a messenger RNA in the liver.
PMID: 3030757 by Izzo P., et al. A new human species of aldolase A mRNA from fibroblasts.