This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Amphiphysin.
.
Human | |
---|---|
Gene Name: | AMPH |
Uniprot: | P49418 |
Entrez: | 273 |
Belongs to: |
---|
No superfamily |
AMPH; AMPH1; amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin I; Amphiphysin
Mass (kDA):
76.257 kDA
Human | |
---|---|
Location: | 7p14.1 |
Sequence: | 7; NC_000007.14 (38383694..38631567, complement) |
Neurons, certain endocrine cell types and spermatocytes.
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
The Boster Bio C3 Marker is available for purchase from the manufacturer. This antibody is approved to be used in IHC and WB applications. It reacts to Human C3b. It is available in liquid and powder form and can be used for diagnostic and research purposes. Read on to learn more. Here are the Top Uses for The C3 Marker
Boster Bio FSHR has been tested in a variety laboratory environments including mice to determine its FSH binding ability. The mice were either treated with FSH or left untreated for 48 hours. Following these treatments, the mice were fixed with 44% paraformaldehyde and embedded in paraffin wax. The paraffin wax sections then had to be deparaffinized and blocked with BSA-PBS 5.
The FSHR gene encodes a transmembranehormone receptor. It is a member of the G protein-coupled receptors family. Fluorescence in situ hybridization has located the FSHR gene on chromosome 2p21. This gene is also essential for gonad development. Variations in the gene can cause ovarian or gonad dysgenesis. The Boster Bio FSHR markers have been validated with positive and negative samples.
The FSHR marker is useful in monitoring OHSS and determining the cause of OHSS. The FSHR indicator is used to measure haptoglobin and fibrinogen. These are all important factors in coagulation. It also measures arterial restructuring. These markers allow doctors to diagnose and manage patients at risk of OHSS.
In human samples, the Boster Bio FSHR marker is able to identify four FSHR isoforms. The FSHR gene encodes four transcripts with a different mRNA structure. These variants don't have identical cell functions but may be useful in research. There are many potential applications for the Boster FSHR marker. However, it is necessary to continue research in the area.
Boster Bio Anti-ACSM3 Monoplonal immunoglobulin, catalogue number A08748, is a mouse-specific mAb which reacts with the AMP marker on the cytoplasm of cancer cells. This antibody is available for research and can be used in studies in human, mouse or rat tissues. The reductive approach reduces the target protein's backbone to a non-immunogenic eight-amino acid sequence composed of alanine and glycine, which is chosen to suppress the immune response. The immune response is also decreased by the fact that the peptide's backbone is amidated and acetylated at the C and N-terminus.
To test its specificity for AMPylation, 50 ng of anti AMP antibodies were added to the recombinant proteins. This antibody was evaluated for its specificity by detecting the AMPylation of recombinant protein using WB. The antibody was also tested by Western blotting for its sensitivity to detect denatured protein targets. It also shows a low background.
The AMPH-based, anti-AMPY marker can be used to detect AMPylated proteins within human tissue. This antibody has been used to detect AMPylated protein such as eIF2, cdc42, and glycans. Like the other antibodies, it recognizes AMPylated amino acids with high sensitivity.
This anti-AMP antibody can be used in combination with human T cells. The recombinant protein was analyzed by WB with all three monoclonal anti-AMP antibodies. The left panel displays the complete 1G11 representation. The right panel shows the background change in reaction to AMPH antibodies. The results of the experiments demonstrate that the Boster Bio Anti-ACSM3 Monoclonal Antibody uses the AMPH marker
Boster Bio's Anti–GAPDH Picoband antibody is a highly-specific primary antibody that reacts with Zebrafish, Mouse Rat, Rat, and Human. Boster Bio antibodies have been validated on Immunohistochemistry, Western Blotting, and ELISA. The antibody is made from highly purified peptides and is available in two gram and milligram quantities.
The antibody detects Human GAPDH which is a natural enzyme responsible for breaking down proteins. Boster Bio Anti–GAPDH Antibody is available in PBS containing 0.09% of sodium azide. Boster Bio prepares the antibodies by dialysis of PBS and Saturated Ammonium Sulfate precipitation. Its purified product is produced in rabbits immunized with a KLH conjugated synthetic peptide.
Boster bio's GAPDH marker has many applications. By identifying the rGAPDH protein and the plasminogen, we can determine the cause of disease and identify the pathogen. This marker can also be found on cell surfaces of three Mycoplasma species: M. pneumoniae and M. hyopneumoniae.
The Escherichiacoli genome BL21 (DE3) was used as the source for the recombinant gene GAPDH. For 10 minutes, Bacteria cells were incubated in great broth (pH28a) After centrifugation, bacterial cells were freed. SDS/PAGE was used in order to detect the recombinant protein. Western Blotting was performed with anti-His antibody.
This monoclonal antibody targets a specific epitope of Macrosialin CD68 (a human cell surface receptor). It has a high homology with a broad spectrum of other proteins in the human body. Other potential targets of anti-Macrosialin antibodies include HIV, bacterial parasites, and fungal protein. The antigen can also serve as a chemotherapeutic agent, adjuvant, or pharmaceutically acceptable carrier.
This antibody is useful to detect Macrosialin. A protein that promotes cell proliferation and survival. It uses the AMPH markers to identify amino acid residues in Macrosialin. Its AMPH label indicates that the antigen was produced by monoclonal bunt antigen, which is a biotechnological technique. Greaves, Paul Clear, Andrew. Matthews, Janet. Janet. Owen. Andrew. Shanyinde. Milensu. Lister. T. Andrew. Calaminici. Maria. Gribben.
AMPH marker, an amphiphilic-globulin protein, is expressed in high numbers in macrophages. It also serves as an immunostaining agent for monocytes. CD68 is an excellent predictor for cancer patients. However, it has low levels of lymphocytes non-hematopoid, tumor cells and lymphocytes.
This immunogenic composition also includes an important part, the AMPH mark. It can help to select antigens more likely to be evaded. This information is important when selecting antigens for vaccines. The antigens should be homologous but it is possible to make antigenic compositions from heterologous substances.
Boster Bio Antibody-ACSM3 Antibodies offer a wide range of antibodies. They are validated by using samples known to be positive or negative for each target protein. These antibodies can be purchased in PicobandTM format and used for ELISA, Flow Cymetry, or IF. They react with rat, mouse, pig and human.
PMID: 8076697 by David C., et al. Autoimmunity in stiff-man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161.
PMID: 7757077 by Yamamoto R., et al. Primary structure of human amphiphysin, the dominant autoantigen of paraneoplastic stiff-man syndrome, and mapping of its gene (AMPH) to chromosome 7p13-p14.