Acyloxyacyl hydrolase Antibodies

AND AOAH ELISA kits, Acyloxyacyl hydrolase Proteins

Many biological assays use antibodies to detect Acyloxyacyl hydrolase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acyloxyacyl hydrolase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acyloxyacyl hydrolase antibodies...

We validate the specificity of these antibodies to Acyloxyacyl hydrolase by testing them on tissues known to express AOAH positively and negatively. Browse below to find the AOAH antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AOAH Infographic by Boster Bio

All AOAH Products

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Anti-Acyloxyacyl hydrolase AOAH Antibody

Human, Mouse

ELISA, WB

$380
Cat # A08659
100ul

Anti-AOAH Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A08659-1
100 μl/vial

AOAH Overview

Facts about Acyloxyacyl hydrolase.

AOAH 3D structure. Source: alphafold

Acyloxyacyl hydrolase (AOAH)

Removes the secondary (acyloxyacyl-linked) fatty acyl chains in the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145, PubMed:29343645). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory reactions (By similarity).

In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance after infection by Gram-negative bacteria (By similarity). .

Gene Information

Human
Gene Name:	AOAH
Uniprot:	P28039
Entrez:	313

Family

Belongs to:

No superfamily

Alternative Names

acyloxyacyl hydrolase (neutrophil); acyloxyacyl hydrolase; EC 3.1.1.77

Molecular Weight

Mass (kDA):
65.105 kDA

Genomic Context


Human

Location:	7p14.2
Sequence:	7; NC_000007.14 (36509313..36724549, complement)

Subcellular Localizations

Secreted. Cytoplasmic vesicle. Detected in urine.

Diseases

Bacterial Infections
Gram-negative Bacterial Infections
Inflammatory Response
Hepatomegaly
Rhinorrhea
Escherichia Coli Infections
Asthma
Mastitis, Bovine
Chronic Sinusitis
Leukopenia
Sinusitis
Inflammation

Stomach Neoplasms
Communicable Diseases
Polyps
Keratoconjunctivitis Sicca
Ulcer
Mastitis

Pathways

Inflammatory Response
Pathogenesis
Transport
Acute Inflammatory Response
Blood Coagulation
Cell Proliferation
Proteolysis
Immune Response
Metaphase
Localization
Neutrophil Activation

Reverse Transcription
Coagulation
Cell Cycle
Protein Folding
Innate Immune Response
Secretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOAH

References

PMID: 1883828 by Hagen F.S., et al. Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides.

PMID: 8089145 by Staab J.F., et al. A saposin-like domain influences the intracellular localization, stability, and catalytic activity of human acyloxyacyl hydrolase.