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Aldehyde oxidase Antibodies
AND AOX1 ELISA kits, Aldehyde oxidase Proteins
Many biological assays use antibodies to detect Aldehyde oxidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aldehyde oxidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aldehyde oxidase antibodies...
Designing a Western blot for Aldehyde oxidase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AOX1 Western Blot GuideDesigning an IHC experiment for Aldehyde oxidase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AOX1 IHC GuideAOX1 Infographic by Boster Bio
All AOX1 Products
Product
Figures
Specificity
Applications
Price
Human
$960
Cat # LS000316
20 µg, 100 µg
Cat # LS000316
20 µg, 100 µg
AOX1 Overview
Facts about Aldehyde oxidase.
Aldehyde oxidase (AOX1)
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N- methylphthalazinium and phthalazine, in addition to aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents.
Participates in the bioactivation of prodrugs like famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antibacterial agent. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen.
Gene Information
| Human | |
|---|---|
| Gene Name: | AOX1 |
| Uniprot: | Q06278 |
| Entrez: | 316 |
Family
| Belongs to: |
|---|
| xanthine dehydrogenase family |
Alternative Names
Aldehyde Oxidase 1; aldehyde oxidase; AOAOH1; AOX1; EC 1.2.3.1
Molecular Weight
Mass (kDA):
147.918 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q33.1 |
| Sequence: | 2; NC_000002.12 (200585952..200677064) |
Tissue Specificity
Abundant in liver, expressed in adipose tissue and at lower levels in lung, skeletal muscle, pancreas. In contrast to mice, no significant gender difference in AOX1 expression level (at protein level).
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Physiological Stress
- Hepatitis B
- Tumor Angiogenesis
- Hepatitis
- Influenza
- Carcinoma
- Melanoma
- Tissue Adhesions
- Malignant Tumor Of Colon
- Headache
- Chimera Disorder
Pathways
- Secretion
- Fermentation
- Glycosylation
- Mating
- Transport
- Cell Growth
- Electron Transport
- Localization
- Cell Proliferation
- Proteolysis
- Angiogenesis
- Cell Death
- Secretory Pathway
PTMs
- Glycosylation
- Cleavage
- Oxidation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AOX1
bosterbio.com/bosterbio-gene-info-cards/AOX1
References
PMID: 8248161 by Wright R.M., et al. cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase.
PMID: 11302742 by Ichida K., et al. Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II.