APBB1IP Antibodies

AND APBB1IP ELISA kits, APBB1IP Proteins

Many biological assays use antibodies to detect APBB1IP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with APBB1IP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop APBB1IP antibodies...

We validate the specificity of these antibodies to APBB1IP by testing them on tissues known to express APBB1IP positively and negatively. Browse below to find the APBB1IP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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APBB1IP Infographic by Boster Bio

All APBB1IP Products

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Anti-RIAM/APBB1IP Antibody Picoband®

3 Q&As

Western blot analysis of APBB1IP using anti-APBB1IP antibody (PA1960 )

Anti-RIAM antibody, PA1960, ICCICC: JURKAT Cell

Anti-RIAM antibody, PA1960, IHC(P)IHC(P): Human Tonsil Tissue

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # PA1960
100 μg/vial

Anti-RIAM (APBB1IP) Mouse Monoclonal Antibody [Clone ID: OTI6E3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APBB1IP (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 3 different cell lines by using anti-APBB1IP monoclonal antibody (1:500)

Human

IHC, WB

$523
Cat # M07280
100 µl

RIAM (APBB1IP) (NM_019043) Human Over-expression Lysate

Human

$628
Cat # LS054518
20 µg, 100 µg

APBB1IP Overview

Facts about Amyloid beta A4 precursor protein-binding family B member 1-interacting protein.

APBB1IP 3D structure. Source: alphafold

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP)

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE.

Mediates Rap1- induced adhesion. .

Gene Information

Human
Gene Name:	APBB1IP
Uniprot:	Q7Z5R6
Entrez:	54518

Family

Belongs to:

MRL family

Alternative Names

amyloid beta (A4) precursor protein-binding, family B, member 1 interactingprotein; amyloid beta A4 precursor protein-binding family B member 1-interacting protein; APBB1-interacting protein 1; APBB1IP; INAG1; PREL1; PREL-1; proline rich EVH1 ligand 1; Proline-rich EVH1 ligand 1; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; Rap1-interacting adaptor molecule; RARP1; Retinoic acid-responsive proline-rich protein 1; RIAM; RIAMRARP-1

Molecular Weight

Mass (kDA):
73.183 kDA

Genomic Context


Human

Location:	10p12.1
Sequence:	10; NC_000010.11 (26438324..26567879)

Tissue Specificity

Widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns(5)P and PtdIns(3)P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases (By similarity).