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- Table of Contents
Facts about Rho GTPase-activating protein 18.
Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which then reduces nuclear localization of YAP1.
| Mouse | |
|---|---|
| Gene Name: | Arhgap18 |
| Uniprot: | Q8K0Q5 |
| Entrez: | 73910 |

| Belongs to: |
|---|
| No superfamily |

bA307O14.2; MacGAP; MGC126757; Rho GTPase activating protein 18; rho-type GTPase-activating protein 18
Mass (kDA):
74.93 kDA

| Mouse | |
|---|---|
| Location: | 10|10 A4 |
| Sequence: | 10; |



PMID: 21865595 by Maeda M., et al. ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility.