Product Info Summary
SKU: | A08418-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-ARHGAP18 Antibody
SKU/Catalog Number
A08418-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ARHGAP18 Antibody (Catalog # A08418-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ARHGAP18 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ARHGAP18 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08418-1)
Host
Rabbit
Contents
ARHGAP18 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ARHGAP18 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ARHGAP18. The immunogen is located within the last 50 amino acids of ARHGAP18.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This STEAP2 antibody does not cross-react with other STEAP proteins.
Reactive Species
A08418-1 is reactive to Arhgap18 in Human, Mouse, Rat
Applications
A08418-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
74.93kDa
Background of Arhgap18
ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ARHGAP18 antibody can be used for detection of ARHGAP18 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of ARHGAP18 in 3T3 cell lysate with ARHGAP18 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 2.5 μg/mL.
Click image to see more details
Immunofluorescence of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For Arhgap18 (Source: Uniprot.org, NCBI)
Gene Name
Arhgap18
Full Name
Rho GTPase-activating protein 18
Weight
74.93kDa
Alternative Names
bA307O14.2; MacGAP; MGC126757; Rho GTPase activating protein 18; rho-type GTPase-activating protein 18 Arhgap18|4833419J07Rik, AI314906, AI843501|Rho GTPase activating protein 18|rho GTPase-activating protein 18|rho-type GTPase-activating protein 18
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Arhgap18, check out the Arhgap18 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Arhgap18: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ARHGAP18 Antibody (A08418-1)
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