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- Table of Contents
Apolipoprotein A-I Antibodies
AND APOA1 ELISA kits, Apolipoprotein A-I Proteins
Many biological assays use antibodies to detect Apolipoprotein A-I, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein A-I in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein A-I antibodies...
Designing a Western blot for Apolipoprotein A-I? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the APOA1 Western Blot GuideAPOA1 Infographic by Boster Bio
All APOA1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1456
96 wells/kit, with removable strips.
Cat # EK1456
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ1456
For 5 plates, 96 wells each
Cat # EZ1456
For 5 plates, 96 wells each
Anti-Apolipoprotein A I/APOA1 Antibody Picoband®
1 Citations
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9916
100 μg/vial
Cat # PB9916
100 μg/vial
Human
ELISA
$499
Cat # FEK1456
96 wells/kit, with removable strips.
Cat # FEK1456
96 wells/kit, with removable strips.
Anti-Apolipoprotein A I/APOA1 Antibody Picoband®
1 Citations
Mouse
IHC, WB
$370
Cat # PB9844
100 μg/vial
Cat # PB9844
100 μg/vial
Human
WB, ELISA (Cap)
$370
Cat # M00717-1
100 μg/vial
Cat # M00717-1
100 μg/vial
Human
$628
Cat # LS000335
20 µg, 100 µg
Cat # LS000335
20 µg, 100 µg
APOA1 Overview
Facts about Apolipoprotein A-I.
Apolipoprotein A-I (APOA1)
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | APOA1 |
| Uniprot: | P02647 |
| Entrez: | 335 |
Family
| Belongs to: |
|---|
| apolipoprotein A1/A4/E family |
Alternative Names
Alp-1; APOA1; Apo-AI; apoA-I; Apolipoprotein A1; Apolipoprotein AI; Apolipoprotein A-I; Brp-14; Ltw-1; Lvtw-1; MGC117399; Sep-1; Sep-2
Molecular Weight
Mass (kDA):
30.778 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.3 |
| Sequence: | 11; NC_000011.10 (116835751..116837950, complement) |
Tissue Specificity
Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.
Subcellular Localizations
Secreted.
Diseases
- Atherosclerosis
- Cardiovascular Diseases
- Diabetes Mellitus
- Coronary Heart Disease
- Obesity
- Dyslipidemias
- Coronary Artery Disease
- Heart Diseases
- Hyperlipidemia
- Hypertensive Disease
- Inflammation
- Hypercholesterolemia
Interacting Proteins
- ABCA1
- APP
- CMTM5
- FGA
- HP
- LCAT
Pathways
- Transport
- Cholesterol Efflux
- Cholesterol Transport
- Reverse Cholesterol Transport
- Secretion
- Pathogenesis
- Cholesterol Homeostasis
- Excretion
- Coagulation
- Aging
- Lipid Transport
- Localization
- Inflammatory Response
PTMs
- Oxidation
- Phosphorylation
- Cleavage
- Glycosylation
- Acetylation
Research Areas
- Biologically Active Proteins
- Breast Cancer
- Cancer
- Diabetes Research
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOA1
bosterbio.com/bosterbio-gene-info-cards/APOA1
References
PMID: 6406984 by Shoulders C.C., et al. Gene structure of human apolipoprotein A1.
PMID: 6304641 by Cheung P., et al. Nucleotide sequence of cloned cDNA of human apolipoprotein A-I.
4 Publications of Boster Apolipoprotein A-I Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.jprot.2020.104098, Rapid glycosylation analysis of mouse serum glycoproteins separated by supported...
- PubMed ID: 34103620, Xiang Y,Zheng Y,Liu S,Liu G,Li Z,Dong W.Comparison of the sensitivity of Western...
- PubMed ID: 26053398, Detection of Serum Protein Biomarkers for the Diagnosis and Staging of Hepatobla...
- PubMed ID: 29618920, Ding N, Luo S, Yu J, Zhou Y, Wu Z. Mol Vis. 2018 Mar 26;24:252-260. eCollection ...
*More publications can be found for each product on its corresponding product page