B2 bradykinin receptor Antibodies

AND BDKRB2 ELISA kits, B2 bradykinin receptor Proteins

Many biological assays use antibodies to detect B2 bradykinin receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with B2 bradykinin receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop B2 bradykinin receptor antibodies...

We validate the specificity of these antibodies to B2 bradykinin receptor by testing them on tissues known to express BDKRB2 positively and negatively. Browse below to find the BDKRB2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for B2 bradykinin receptor? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the BDKRB2 IHC Guide

BDKRB2 Infographic by Boster Bio

All BDKRB2 Products

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Anti-BDKRB2 Monoclonal Antibody

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Western blot analysis of BDKRB2 using anti-BDKRB2 antibody (M03117)

IHC analysis of BDKRB2 using anti-BDKRB2 antibody (M03117)

Human, Mouse

IP, IHC, WB

$370
Cat # M03117
100 μl

Anti-BDKRB2 Antibody Picoband®

Western blot analysis of BDKRB2 using anti-BDKRB2 antibody (PB9396)

Human, Mouse, Rat

$370
Cat # PB10047
100 μg/vial

BDKRB2 Overview

Facts about B2 bradykinin receptor.

BDKRB2 3D structure. Source: alphafold

B2 bradykinin receptor (BDKRB2)

Receptor for bradykinin.
It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene Information

Human
Gene Name:	BDKRB2
Uniprot:	P30411
Entrez:	624

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

B2 bradykinin receptor; B2R; BDKRB2; BK-2 receptor; BK2; BK-2; BKR2; Bradykinin RB2; bradykinin receptor B2; BradykininRB2; BRB2; DKFZp686O088

Molecular Weight

Mass (kDA):
44.461 kDA

Genomic Context


Human

Location:	14q32.2
Sequence:	14; NC_000014.9 (96204798..96244329)

Tissue Specificity

Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Hypertensive Disease
Essential Hypertension
Inflammation
Cholangiocarcinoma
Malignant Neoplasms
Neoplasms
Coughing
Cardiovascular Diseases
Stomach Neoplasms
Carcinoma
Pain
Anxiety Disorders
Heart Failure

Diabetes Mellitus
Panic Disorder
Hyperalgesia
Cardiac Complication
Cell Invasion
Malignant Neoplasm Of Stomach
Kidney Diseases

Interacting Proteins

KNG1

Pathways

Transport
Vasodilation
Cell Proliferation
Dna Methylation
Methylation
Pathogenesis
Secretion
Hyperphosphorylation
Cell Migration
Smooth Muscle Contraction
Insulin Secretion
Tube Formation
Ion Transport

Muscle Contraction
Localization
Inflammatory Response
Glucose Homeostasis
Reverse Transcription
Sensitization
Cell Growth

PTMs

Phosphorylation
Methylation

Demethylation
Acetylation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BDKRB2

References

PMID: 1314587 by Hess J.F.R., et al. Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.

PMID: 7916737 by Powell S.J., et al. Human bradykinin B2 receptor: nucleotide sequence analysis and assignment to chromosome 14.