Bcl-2-modifying factor Antibodies

AND BMF ELISA kits, Bcl-2-modifying factor Proteins

Many biological assays use antibodies to detect Bcl-2-modifying factor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bcl-2-modifying factor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bcl-2-modifying factor antibodies...

We validate the specificity of these antibodies to Bcl-2-modifying factor by testing them on tissues known to express BMF positively and negatively. Browse below to find the BMF antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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BMF Infographic by Boster Bio

All BMF Products

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Specificity

Applications

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Anti-Bcl-2-modifying factor Bmf Antibody

Western blot analysis of Bmf expression in HepG2 cell lysate with Bmf antibody at (A) 2

Human

ELISA, IF, IHC-P, WB

$481
Cat # A02432
0.1 mg

Anti-Bcl-2-modifying factor Bmf Antibody

Western blot analysis of Bmf in 293 cell lysate with Bmf antibody at (A) 1 and (B) 2 μg/ml

Immunocytochemistry of Bmf in HeLa cells with Bmf antibody at 10 μg/mL

Immunofluorescence of Bmf in HeLa cells with Bmf antibody at 5 μg/mL

Human, Mouse

ELISA, ICC, WB

$481
Cat # A02432-1
0.1 mg

BMF (NM_033503) Human Recombinant Protein

$1249
Cat # PROTQ96LC9
20 µg

Anti-BMF Mouse Monoclonal Antibody [Clone ID: OTI6F3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BMF (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BMF mouse monoclonal antibody

Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-BMF mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M02432
100 µl

Anti-Bmf Rabbit Monoclonal Antibody

Western blot analysis of Bmf expression in Ramos cell lysate

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M02432-1
100 μl/vial

BMF Overview

Facts about Bcl-2-modifying factor.

BMF 3D structure. Source: alphafold

Bcl-2-modifying factor (BMF)

May play a role in apoptosis. Isoform 1 appears to be the primary initiator.

Gene Information

Human
Gene Name:	BMF
Uniprot:	Q96LC9
Entrez:	90427

Family

Belongs to:

Bcl-2 family

Alternative Names

Bcl2 modifying factor; bcl-2-modifying factor; FLJ00065

Molecular Weight

Mass (kDA):
20.508 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (40087890..40108879, complement)

Tissue Specificity

Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.

Diseases

Malignant Neoplasms
Neoplasms
Leukemia
Pancytopenia
Acute Lymphocytic Leukemia
Anemia
Tissue Adhesions
Malignant Paraganglionic Neoplasm
Carcinoma
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Lymphoma
Malignant Neoplasm Of Breast

Aplastic Anemia
Lymphoid Leukemia
Mammary Neoplasms
Fanconi Anemia
Bone Marrow Diseases
Dysmyelopoietic Syndromes
Fibrosis

Interacting Proteins

BCL2L1
BCL2L2
DYNLL2
REL
SEC14L4

TFIP11

Pathways

Cell Death
Localization
Anoikis
Cell Cycle
Cell Proliferation
Transport
Cell Growth
Induction Of Apoptosis
Secretion
Programmed Cell Death
Cell Adhesion
Pathogenesis
Cell Maturation

Gene Silencing
Senescence
Autophagy
Cell Migration
Necroptosis
Tissue Homeostasis
Cell Cycle Arrest

PTMs

Phosphorylation
Cleavage
Acetylation

Bromination
Demethylation
Glycosylation

Research Areas

Apoptosis
Cancer
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BMF

References

PMID: 11546872 by Puthalakath H., et al. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.

PMID: 14574334 by Morales A.A., et al. Expression and transcriptional regulation of functionally distinct Bmf isoforms in B-chronic lymphocytic leukemia cells.