- Table of Contents
We validate the specificity of these antibodies to Carbonic anhydrase 2 by testing them on tissues known to express CA2 positively and negatively. Browse below to find the CA2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Facts about Carbonic anhydrase 2.
Can hydrate cyanamide into urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.
|alpha-carbonic anhydrase family|
CA2; CAII; CA-IIEC 126.96.36.199; Car2; Carbonate dehydratase II; carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic Anhydrase II; carbonic anhydrase IICAC; carbonic dehydratase
|Sequence:||8; NC_000008.11 (85463902..85481493)|
Cytoplasm. Cell membrane. Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
The CA2 Marker antibody from Boster Bio targets CD235a and glycophorin A. It is validated for IHC applications and is formulated in 10mM PBS containing 0.05% BSA and azide. You can also purchase blocking peptide to avoid cross-reactivity. Boster Bio antibodies are validated for WB, IHC, Immunofluorescence, and ELISA.
Several techniques have been developed to detect the TMEM16A/ANO1 protein. One such technique is co-immunoprecipitation, which uses the CA2 marker as the antigen. Another technique is immunofluorescence, which uses the LC3B-II marker to detect TMEM16A. These two methods are useful for determining the presence of TMEM16A in various tissues.
TMEM16A/ANO1 is a calcium-activated chloride channel. It is implicated in generating slow waves in the GI tract. In a rat model of chronic water avoidance stress, the role of TMEM16A in IBS was determined by fecal water content and intestinal transit time. Additionally, the visceral motor response was measured to colorectal distension. Moreover, TMEM16A expression in the intestines was evaluated by immunofluorescence and Western blot.
Using the CA2 marker, a Boster Bio Anti-TMEM16A antibody is highly effective in blocking Cl Ca currents in cerebral arteries. In fact, it decreased Cl Ca current density in isolated SMCs by 68%, indicating that TMEM16A is involved in the generation of Cl Ca currents in cerebral arteries. It is important to understand that TMEM16A is not the only protein that generates Cl Ca currents in the artery.
The Anti-TMEM16A/ANO1/ANO1 anti-Mouse antibody is a highly specific anti-TMEM16A/ANO1 antibody that recognizes the CA2 marker in living cells. In western blot and immunohistochemistry, this antibody recognizes Anoctamin-1 from mouse tissues. It is compatible with Human, Mouse, and Rat.
The Glycophorin A / CD235b Antibody from Boster Bio recognizes the 39-kD sialoglycoprotein. This protein is abundantly expressed on red blood cells. Moreover, it is the target of the influenza virus and Plasmodium falciparum. Glycophorin A and B have similar phenotypes and are closely related. However, there are some differences in their antigenicity. This is a result of the fact that they recognize different epitopes on the same molecule.
This antibody recognizes Human Glycophorin A and CD235a, two single-pass membrane sialoglycoproteins. This antibody binds weakly to GPB and agglutinates RBCs in a non-specific manner. Therefore, it is useful in erythroid cell development and research. The antigen HIR2 is expressed on early and late erythroid precursors as well as mature erythrocytes. This antibody is suitable for immunohistochemistry studies.
The TCA is an antibody-like molecule with three polypeptide subunits. Two of the subunits are the light chain and heavy chain of a monoclonal antibody. The third polypeptide is the CH domain. The two chains contain functional antigen-binding fragments known as CH domains. The light chain/heavy chain pair is highly specific for the first antigen.
The CD235a antibody from Boster Bio detects the CD235a protein and Glycophorin A. The antibody is also available in the form of heavy chain only antibodies. These antibodies contain the heavy chain and the antigen-binding domain, and can be dimers, monomers, or multimers. Anti-Glycophorin A / CD235a Antibody from Boster Bio is a useful tool in determining the antigen in human cells.
Monoclonal antibodies are highly specific. They target one antigenic site. Compared with polyclonal antibodies, monoclonal antibodies are produced from a population of homogeneous cells. These monoclonal antibodies are isolated from phage antibody libraries. These antibodies are highly specific and have the advantage of being uncontaminated with other antibodies. The monoclonal antibody from Boster Bio also has excellent bioactivity.
The clinical significance of the anti-Glycophorin A /CD235a Antibody from Boster Bio is also known. The study examined the clinical consequences of different antibody specificities, particularly for the infant. It was discovered that pregnant women who received the anti-Glycophorin A / CD235a antibody from Boster Bio were more likely to undergo therapeutic intervention. However, in some women, combining both antibodies would prove harmful.
Besides the biological importance of Glycophorin A/CD235a antibodies, the Fc-receptors of human antibodies play important roles in the antigen-antibody interaction. These antibodies also have the ability to regulate cell surface receptors. This means that they can bind to antigens and inhibit the growth of tumor cells. Thus, the anti-Glycophorin A/CD235a antibody is a powerful tool to treat cancer cells.
The CD235a antibody from Boster Bio is designed to recognize the CD344 and CD235a antigens on red blood cells. It also recognizes the proteins that cause cancer. Flow-induced detachment refers to the process by which red blood cells adhere to surfaces by specific antigen-antibody bonds. This process is known as flow-induced detachment.
*More publications can be found for each product on its corresponding product page