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- Table of Contents
Carbonic anhydrase 2 Antibodies
AND CA2 ELISA kits, Carbonic anhydrase 2 Proteins
Many biological assays use antibodies to detect Carbonic anhydrase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carbonic anhydrase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carbonic anhydrase 2 antibodies...
Designing a Western blot for Carbonic anhydrase 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CA2 Western Blot GuideCA2 Infographic by Boster Bio
All CA2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$750
Cat # EK0681
96 wells/kit, with removable strips.
Cat # EK0681
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00143
100 μg/vial
Cat # M00143
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9989
100 μg/vial
Cat # PB9989
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M00143-2
100 μl/vial
Cat # M00143-2
100 μl/vial
Human
$628
Cat # LS000760
20 µg, 100 µg
Cat # LS000760
20 µg, 100 µg
CA2 Overview
Facts about Carbonic anhydrase 2.
Carbonic anhydrase 2 (CA2)
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide.
Can hydrate cyanamide into urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.
Gene Information
| Human | |
|---|---|
| Gene Name: | CA2 |
| Uniprot: | P00918 |
| Entrez: | 760 |
Family
| Belongs to: |
|---|
| alpha-carbonic anhydrase family |
Alternative Names
CA2; CAII; CA-IIEC 4.2.1.1; Car2; Carbonate dehydratase II; carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic Anhydrase II; carbonic anhydrase IICAC; carbonic dehydratase
Molecular Weight
Mass (kDA):
29.246 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q21.2 |
| Sequence: | 8; NC_000008.11 (85463902..85481493) |
Subcellular Localizations
Cytoplasm. Cell membrane. Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Diseases
- Epilepsy
- Ischemia
- Alzheimer's Disease
- Nerve Degeneration
- Nervousness
- Brain Injuries
- Brain Ischemia
- Epilepsy, Temporal Lobe
- Transient Ischemic Attack
- Cerebral Ischemia
- Schizophrenia
- Sclerosis
Pathways
- Localization
- Cell Death
- Aging
- Pathogenesis
- Innervation
- Neuroprotection
- Transport
- Cognition
- Brain Development
- Synaptic Transmission
- Neurogenesis
- Secretion
- Response To Stress
PTMs
- Phosphorylation
- Cleavage
- Reduction
- Oxidation
- Carboxylation
- Amidation
- Citrullination
Research Areas
- Hypoxia
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CA2
bosterbio.com/bosterbio-gene-info-cards/CA2
References
PMID: 3108857 by Montgomery J.C., et al. Nucleotide sequence of human liver carbonic anhydrase II cDNA.
PMID: 3121496 by Murakami H., et al. Cloning, expression, and sequence homologies of cDNA for human carbonic anhydrase II.
2 Publications of Boster Carbonic anhydrase 2 Antibodies & ELISA Kits
- PubMed ID: 22547769, Calcium-and integrin-binding protein-1 and calcineurin are upregulated in the ri...
- PubMed ID: 30210689, Transcription factor Tbx18 induces the differentiation of c-kit canine mesenchym...
*More publications can be found for each product on its corresponding product page