Carbonic anhydrase 2 Antibodies

AND CA2 ELISA kits, Carbonic anhydrase 2 Proteins

Many biological assays use antibodies to detect Carbonic anhydrase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Carbonic anhydrase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Carbonic anhydrase 2 antibodies...

We validate the specificity of these antibodies to Carbonic anhydrase 2 by testing them on tissues known to express CA2 positively and negatively. Browse below to find the CA2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CA2 Infographic by Boster Bio

All CA2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Carbonic Anhydrase II/CA2 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9989
100 μg/vial

Anti-CA2 Antibody Picoband® (monoclonal, 10E11)

1 Citations 6 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00143
100 μg/vial

Human CA2 / Carbonic Anhydrase 2 ELISA Kit PicoKine®

1 Citations 6 Q&As

Human

ELISA

$750
Cat # EK0681
96 wells/kit, with removable strips.

Carbonic Anhydrase II (CA2) (NM_000067) Human Recombinant Protein

$1062
Cat # PROTP00918
20 µg

Anti-Carbonic anhydrase 2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M00143-2
100 μl/vial

CA2 Overview

Facts about Carbonic anhydrase 2.

CA2 3D structure. Source: alphafold

Carbonic anhydrase 2 (CA2)

Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide.

Can hydrate cyanamide into urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.

Gene Information

Human
Gene Name:	CA2
Uniprot:	P00918
Entrez:	760

Family

Belongs to:

alpha-carbonic anhydrase family

Alternative Names

CA2; CAII; CA-IIEC 4.2.1.1; Car2; Carbonate dehydratase II; carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic Anhydrase II; carbonic anhydrase IICAC; carbonic dehydratase

Molecular Weight

Mass (kDA):
29.246 kDA

Genomic Context


Human

Location:	8q21.2
Sequence:	8; NC_000008.11 (85463902..85481493)

Subcellular Localizations

Cytoplasm. Cell membrane. Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.

Diseases

Epilepsy
Ischemia
Alzheimer's Disease
Nerve Degeneration
Nervousness
Brain Injuries
Brain Ischemia
Epilepsy, Temporal Lobe
Transient Ischemic Attack
Cerebral Ischemia
Schizophrenia
Sclerosis

Depressive Disorder
Neurofibrillary Tangles
Dementia
Neurodegenerative Disorders
Kindling, Neurologic
Hypoxia

Pathways

Localization
Cell Death
Aging
Pathogenesis
Innervation
Neuroprotection
Transport
Cognition
Brain Development
Synaptic Transmission
Neurogenesis
Secretion
Response To Stress

Cellular Localization
Programmed Cell Death
Reverse Transcription
Swimming
Senescence
Segmentation
Lactation

PTMs

Phosphorylation
Cleavage
Reduction
Oxidation
Carboxylation
Amidation
Citrullination

Dephosphorylation
Ribosylation
Iodination
Nitration
Glycosylation
Acetylation
Methylation

Deglycosylation

Research Areas

Hypoxia
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CA2

References

PMID: 3108857 by Montgomery J.C., et al. Nucleotide sequence of human liver carbonic anhydrase II cDNA.

PMID: 3121496 by Murakami H., et al. Cloning, expression, and sequence homologies of cDNA for human carbonic anhydrase II.

2 Publications of Boster Carbonic anhydrase 2 Antibodies & ELISA Kits

PubMed ID: 22547769, Calcium-and integrin-binding protein-1 and calcineurin are upregulated in the ri...
PubMed ID: 30210689, Transcription factor Tbx18 induces the differentiation of c-kit canine mesenchym...

*More publications can be found for each product on its corresponding product page