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- Table of Contents
Caveolin-1 Antibodies
AND CAV1 ELISA kits, Caveolin-1 Proteins
Many biological assays use antibodies to detect Caveolin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caveolin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caveolin-1 antibodies...
Designing a Western blot for Caveolin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CAV1 Western Blot GuideCAV1 Infographic by Boster Bio
All CAV1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, WB
$370
Cat # PB9165
100 μg/vial
Cat # PB9165
100 μg/vial
Human
IF, IHC, IHC-F, WB
$370
Cat # M00179-1
100 μg/vial
Cat # M00179-1
100 μg/vial
Anti-Caveolin-1/CAV1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # PA1514
100 μg/vial
Cat # PA1514
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00179
100 μl
Cat # M00179
100 μl
Human, Mouse, Rat
Flow Cytometry, IHC, ICC, WB
$370
Cat # PB9329
100 μg/vial
Cat # PB9329
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00179-4
20μL, 40μL, 100μL, 200μL
Cat # M00179-4
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2367
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2367
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1094
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1094
1 kit, containing one 96-well plate and all necessary reagents
CAV1 Overview
Facts about Caveolin-1.
Caveolin-1 (CAV1)
Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation.
Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Gene Information
| Human | |
|---|---|
| Gene Name: | CAV1 |
| Uniprot: | Q03135 |
| Entrez: | 857 |
Family
| Belongs to: |
|---|
| caveolin family |
Alternative Names
CAV; CAV1; caveolae protein, 22kD; caveolin 1, caveolae protein, 22kDa; Caveolin1; Caveolin-1; cell growth-inhibiting protein 32; MSTP085; VIP21
Molecular Weight
Mass (kDA):
20.472 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q31.2 |
| Sequence: | 7; NC_000007.14 (116525009..116561185) |
Tissue Specificity
Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Expressed in the brain.
Subcellular Localizations
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Golgi apparatus, trans-Golgi network. Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Tissue Adhesions
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Cell Invasion
- Inflammation
- Adenocarcinoma
Interacting Proteins
- Axin1
- BID
- CAV2
- CAVIN1
- CAVIN2
- CAVIN3
- EGFR
- F2R
- FAS
- Grb7
Pathways
- Localization
- Transport
- Endocytosis
- Pathogenesis
- Cell Proliferation
- Secretion
- Angiogenesis
- Cell Cycle
- Cell Migration
- Cell Growth
- Transcytosis
- Cell Adhesion
- Cholesterol Transport
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Palmitoylation
- Reduction
- Biotinylation
- Oxidation
- Dephosphorylation
- Acylation
- Nitration
Research Areas
- Cancer
- Caveolae Markers
- Cellular Markers
- Cholesterol Metabolism
- Hypoxia
- Lipid and Metabolism
- Lipid Droplets
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAV1
bosterbio.com/bosterbio-gene-info-cards/CAV1
References
PMID: 1360410 by Glenney J.R. Jr.; The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.
PMID: 10086342 by Hurlstone A.F., et al. Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.
4 Publications of Boster Caveolin-1 Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms15058526, MicroRNA-199a-5p Affects Porcine Preadipocyte Proliferation and Differentiation
- PubMed ID: 24830555, MicroRNA-199a-5p Affects Porcine Preadipocyte Proliferation and Differentiation
- PubMed ID: 28656274, Guo, Y., Cui, L., Jiang, S., Zhang, A., & Jiang, S. (2017). Proteomics of acute ...
- PubMed ID: 24175763, Wang Nn, Zhao Lj, Wu Ln, He Mf, Qu Jw, Zhao Yb, Zhao Wz, Li Js, Wang Jh. Asian P...
*More publications can be found for each product on its corresponding product page